1991
Behavioral and receptor binding analysis of the α2-adrenergic agonist, 5-bromo-6 [2-imidazoline-2-YL amino] quinoxaline (UK-14304): evidence for cognitive enhancement at an α2-adrenoceptor subtype
Arnsten A, Leslie FM. Behavioral and receptor binding analysis of the α2-adrenergic agonist, 5-bromo-6 [2-imidazoline-2-YL amino] quinoxaline (UK-14304): evidence for cognitive enhancement at an α2-adrenoceptor subtype. Neuropharmacology 1991, 30: 1279-1289. PMID: 1686301, DOI: 10.1016/0028-3908(91)90024-6.Peer-Reviewed Original Research
1985
Stress produces opioid-like effects on investigatory behavior
Arnsten A, Berridge C, Segal DS. Stress produces opioid-like effects on investigatory behavior. Pharmacology Biochemistry And Behavior 1985, 22: 803-809. PMID: 4011639, DOI: 10.1016/0091-3057(85)90531-3.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsEndorphinsExploratory BehaviorMaleMorphineRatsRats, Inbred StrainsStress, PhysiologicalConceptsOpioid systemInvestigatory behaviorOpiate antagonist naloxoneOpioid-like effectsAntagonist naloxoneStress-induced reductionLocomotor hypoactivityOpiate agonistsNaive ratsLow dosesCharacteristic alterationsGreater reductionAverage timeNovel environmentRatsNumerous reportsBehavioral activityAlterationsExposureNaloxoneStressorsAgonistsHypoactivityDoses
1981
Evidence for an interaction of opioid and noradrenergic locus coeruleus systems in the regulation of environmental stimulus-directed behavior
Arnsten A, Segal DS, Loughlin SE, Roberts D. Evidence for an interaction of opioid and noradrenergic locus coeruleus systems in the regulation of environmental stimulus-directed behavior. Brain Research 1981, 222: 351-363. PMID: 7284783, DOI: 10.1016/0006-8993(81)91038-6.Peer-Reviewed Original ResearchConceptsOpiate agonist morphineNoradrenergic locus coeruleus systemOpiate antagonist naloxoneDorsal bundleSham-lesioned ratsLocus coeruleus systemLocus coeruleus activityStimulus contactStimulus interactionAgonist morphineAntagonist naloxoneOpioid roleInhibitory actionNaloxoneOpioidsReportParticular environmental stimuliMorphineLesionsRats