Women’s Health Research at Yale funds studies on pain relief, cannabis, and genetic origins of sex differences in disease
Women’s Health Research at Yale (WHRY) today announced funding for first-of-their-kind studies on pain relief, cannabis, and the genetic basis of sex differences across a broad range of ailments, including Alzheimer’s disease and heart disease.
Low mobility predicts hospital readmission in older heart attack patients
Close to 20% of elderly adults who have suffered a heart attack will be readmitted to the hospital within 30 days. Performance on a simple mobility test is the best predictor of whether an elderly heart attack patient will be readmitted, a Yale-led study reports.
Antiretroviral Therapy Crucial in Preventing non-Hodgkin Lymphoma, YSPH Study Reinforces
A research team led by the Yale School of Public Health has found that for people living with HIV/AIDS, both recent immunosuppression and prolonged HIV viremia play important and independent roles in the development of non-Hodgkin lymphoma.
Health surrogates for older adults often don’t know their care preferences
When it comes to making health decisions for an older adult, what health surrogates don’t know can be harmful, according to new research. While 75% of surrogates feel extremely confident in their knowledge of a loved one’s preferences, only 21% of them actually know what the older patient would want in the event of a serious illness, the researchers said.
Yale approach bases decision-making on older adults' own health priorities
In a pilot project, researchers at Yale, New York University School of Medicine and Baylor College of Medicine have shown that an innovative approach to health care for older adults with complex health needs can be integrated into a real-world clinical practice. Known as patient priorities care, the approach helps patients and clinicians focus decision-making and health care on what matters most -- namely patients' own health priorities.Source: EurekAlert!
Yale center dedicated to research on older adults receives renewed funding
For the fifth consecutive time, the Yale Claude D. Pepper Older Americans Independence Center (OAIC) has been renewed for funding from the National Institute on Aging (NIA). The Center is one of only two such programs nationwide to receive continuous NIA support since it was first funded in 1992, marking more than 25 years of excellence in geriatrics and aging research under the leadership of Geriatrics Section Chief Dr. Mary Tinetti, Dr. Thomas Gill, and Dr. Terri Fried.
We’re Bad at Evaluating Risk. How Doctors Can Help
Dr. Terri Fried, professor of medicine at Yale and a geriatrician at the VA Connecticut Healthcare System, weighs in on research suggesting that physicians’ recommendations powerfully influence how patients weigh their choices, and that while almost all patients want to know their options, most want their doctor to make the final decision. The greater the uncertainty, the more support they want — but the less likely they are to receive it.Source: The New York Times
Aging impairs innate immune response to flu
Aging impairs the immune system’s response to the flu virus in multiple ways, weakening resistance in older adults, according to a Yale study. The research reveals why older people are at increased risk of illness and death from flu, the researchers said.
Yale researchers receive federal grants to study pain management in veterans, active military members
Three Yale and VA Connecticut Healthcare System research teams have been awarded federal grants as part of a multi-year study of how to manage chronic pain in veterans and active military members without the use of drugs.
Benefits of testosterone therapy in older men are mixed
Older men with low testosterone levels showed improved bone density and strength, as well as reduced anemia, after one year of testosterone therapy, according to a new study conducted at Yale and other sites. The therapy had no impact on cognitive function, however, and may worsen plaque in coronary arteries, said the researchers.
For older hypertension patients, an unwelcome tradeoff
Medications used by many older people to control their blood pressure also increase the risk of serious fall injuries by 30% to 40% — injuries that have a similar effect on mortality and functional loss as the strokes and heart attacks the blood pressure drugs are meant to prevent — according to a new study by Yale School of Medicine researchers in the Feb. 24 issue of JAMA Internal Medicine.
Grilo Guest Co-Editor of Special Issue of Clinical Therapeutics
Carlos Grilo, PhD, Professor of Psychiatry and of Psychology and Director of the Yale Program for Obesity Weight and Eating Research, served as guest co-editor on the January 2021 special issue of Clinical Therapeutics, centered on the topic of eating disorders.
Genetic Analysis of Symptoms Yields New Insights Into PTSD
Attempts to identify the genetic causes of neuropsychiatric diseases such as post-traumatic stress disorder (PTSD) through large-scale genome-wide analyses have yielded thousands of potential links. The challenge is further complicated by the wide range of symptoms exhibited by those who have PTSD. For instance, does extreme arousal, anger, or irritation experienced by some have the same genetic basis as the tendency to re-experience traumatic events, another symptom of the disorder? A new study led by researchers at Yale and the University of California-San Diego (UCSD) provides answers to some of these questions and uncovers intriguing genetic similarities between PTSD and other mental health disorders such as anxiety, bipolar disorder, and schizophrenia.Source: Yale News
Scientists Unravel Mystery of Sex Disparities in COVID-19 Outcomes
"Age and sex are where immunological changes intersect,” says Akiko Iwasaki, PhD. Over the past year, Iwasaki and her colleagues from around the globe have compiled a rich literature of research that reveals in detail these and other factors that make the virus more lethal for men.Source: YaleNews