Publications

2026

Systemic lupus erythematosus-associated neutrophilic dermatoses
Saeed S, Zhou A, Gehlhausen J, Ko C, Koumpouras F, Nelson C, Ramachandran S. Systemic lupus erythematosus-associated neutrophilic dermatoses. JAAD Case Reports 2026, 68: 43-47. DOI: 10.1016/j.jdcr.2025.10.063.
Peer-Reviewed Original Research

2025

MTHFR allele and one-carbon metabolic profile predict severity of COVID-19
Petrova B, Syphurs C, Culhane A, Chen J, Chen E, Cotsapas C, Esserman D, Montgomery R, Kleinstein S, Smolen K, Mendez K, Network I, Lasky-Su J, Steen H, Levy O, Diray-Arce J, Kanarek N. MTHFR allele and one-carbon metabolic profile predict severity of COVID-19. Proceedings Of The National Academy Of Sciences Of The United States Of America 2025, 122: e2509118122. PMID: 41410771, DOI: 10.1073/pnas.2509118122.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
B7-H3 as a Universal Target for Solid Tumor Therapy: Clinical Promise and Biological Complexity.
Huang B, Chen L. B7-H3 as a Universal Target for Solid Tumor Therapy: Clinical Promise and Biological Complexity. Journal Of Clinical Oncology 2025, jco2502487. PMID: 41401407, DOI: 10.1200/jco-25-02487.
Peer-Reviewed Original Research
Klippel‐Feil Syndrome in a Patient Referred for Axial Spondyloarthritis
Tang Z, Buonocore B, Danve A. Klippel‐Feil Syndrome in a Patient Referred for Axial Spondyloarthritis. Arthritis & Rheumatology 2025 PMID: 41392715, DOI: 10.1002/art.70023.
Peer-Reviewed Original Research
Systemic Sclerosis-Associated Interstitial Lung Disease: What We Know and How to Incorporate Guidelines into Clinical Practice
Esposito A, Selvan K, Richardson C, Khanna D, Bemiss B, Bernstein E, Chung J, Cox C, Dematte J, Denton C, Distler O, Hinchcliff M, Smith V, Strek M, Varga J, Hoffmann-Vold A, Volkmann E. Systemic Sclerosis-Associated Interstitial Lung Disease: What We Know and How to Incorporate Guidelines into Clinical Practice. Chest 2025 PMID: 41397518, DOI: 10.1016/j.chest.2025.11.047.
Peer-Reviewed Original Research
Concepts
Gut microbiota of dogs with cancer receiving anti-EGFR/HER2 immunization reveals potential biomarkers of patient survival
Rodrigues R, Karumuru V, Nuss S, Elliott M, Shriver I, Chao C, Berriatua R, Doyle H, Tripp C, Mamula M, Dzutsev A, Morgun A, Shulzhenko N. Gut microbiota of dogs with cancer receiving anti-EGFR/HER2 immunization reveals potential biomarkers of patient survival. Veterinary Oncology 2025, 2: 36. DOI: 10.1186/s44356-025-00048-x.
Peer-Reviewed Original Research
Concepts
Unravelling the Immunological Enigma of Sickle Cell Disease: Current Understanding and Future Directions
Jamwal S, Calhoun C, Mohanty S, Montgomery R, Krishnamurti L, Shaw A, Yildirim I. Unravelling the Immunological Enigma of Sickle Cell Disease: Current Understanding and Future Directions. Immunology 2025 PMID: 41387179, DOI: 10.1111/imm.70080.
Peer-Reviewed Original Research
Concepts
RUNX1 is expressed in a subpopulation of dermal fibroblasts and is associated with disease severity of systemic sclerosis
Parvizi R, Gong Z, Jarnagin H, Toledo D, Abel T, Popovich D, Morrisson M, Wood T, Shenk S, Sarkar M, Plazyo O, Dey P, Coon A, Erba J, Tsoi L, Tsou P, Hinchcliff M, Khanna D, Garlick J, Gudjonsson J, Pioli P, Whitfield M. RUNX1 is expressed in a subpopulation of dermal fibroblasts and is associated with disease severity of systemic sclerosis. Annals Of The Rheumatic Diseases 2025 PMID: 41381303, DOI: 10.1016/j.ard.2025.10.033.
Peer-Reviewed Original Research
Concepts
Dysregulated alveolar type 2 epithelial cell proteostasis promotes fibrogenic macrophage migration inhibitory factor–CD74 signaling
Kim S, Nouws J, Ruwisch J, Woodard G, Cooley J, Khoury J, Sun H, Doherty E, Piecychna M, Manning E, Kang M, Bruscia E, Wei H, Zhang Y, Yarovinsky T, Hwa J, Zacharias W, Ingram J, Lee C, Elias J, Kaminski N, Redente E, Herzog E, Prasse A, Bucala R, Sauler M. Dysregulated alveolar type 2 epithelial cell proteostasis promotes fibrogenic macrophage migration inhibitory factor–CD74 signaling. Science Translational Medicine 2025, 17: eadr2277. PMID: 41337540, DOI: 10.1126/scitranslmed.adr2277.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
High-Risk Penicillin Reaction Flags in the Medical Record
Novotny S, Elmansy L, Kwah J, Liao J, Wong K, Stone C, Belmont A. High-Risk Penicillin Reaction Flags in the Medical Record. JAMA Network Open 2025, 8: e2549081. PMCID: PMC12717615, DOI: 10.1001/jamanetworkopen.2025.49081.
Peer-Reviewed Original Research
Concepts
SA82 Real-World Findings From the Provent Study of Dupilumab Therapy for Severe Asthma: 2-Year Analysis
Lommatzsch M, Korn S, Schmidt O, Timmermann H, Gappa M, Watz H, Kwah J, LEDANOIS O, Nischan N, Hahn M, Heimann A. SA82 Real-World Findings From the Provent Study of Dupilumab Therapy for Severe Asthma: 2-Year Analysis. Value In Health 2025, 28: s661-s662. DOI: 10.1016/j.jval.2025.09.3023.
Peer-Reviewed Original Research
Cam morphology and the risk of developing radiographic hip osteoarthritis within 8 years: an individual participant data meta-analysis of 23 886 hips from the world COACH consortium
Tang J, Boel F, van Buuren M, Riedstra N, van den Berg M, Ahedi H, Arden N, Bierma-Zeinstra S, Boer C, Cicutini F, Cootes T, Crossley K, Felson D, Gielis W, Heerey J, Jones G, Kluzek S, Lane N, Lindner C, Lynch J, van Meurs J, Mosler A, Nelson A, Nevitt M, Oei E, Runhaar J, Weinans H, Agricola R. Cam morphology and the risk of developing radiographic hip osteoarthritis within 8 years: an individual participant data meta-analysis of 23 886 hips from the world COACH consortium. British Journal Of Sports Medicine 2025, bjsports-2025-110144. PMID: 41314784, DOI: 10.1136/bjsports-2025-110144.
Peer-Reviewed Original Research
A Guide for Initiating and Managing Chimeric Antigen Receptor T Cell Therapy Clinical Trials in Autoimmune Rheumatic Diseases
Caricchio R, Bell S, Bernatsky S, Dall'Era M, Goddard D, Kalunian K, Kim A, Koumpouras F, Rubio J, Saxena A, Sheikh S, Network T. A Guide for Initiating and Managing Chimeric Antigen Receptor T Cell Therapy Clinical Trials in Autoimmune Rheumatic Diseases. ACR Open Rheumatology 2025, 7: e70139. PMID: 41315006, PMCID: PMC12662744, DOI: 10.1002/acr2.70139.
Peer-Reviewed Original Research
Concepts
One Allergy, Two Paths: Navigating Penicillin Evaluation in Pregnant Patients Direct Challenges vs Penicillin Skin Testing in Pregnancy: A Controversies in Allergy Review
Belmont A, Li L, Tsao L, Valente M, Wolfson A, Copaescu A. One Allergy, Two Paths: Navigating Penicillin Evaluation in Pregnant Patients Direct Challenges vs Penicillin Skin Testing in Pregnancy: A Controversies in Allergy Review. The Journal Of Allergy And Clinical Immunology In Practice 2025 PMID: 41319903, PMCID: PMC12690565, DOI: 10.1016/j.jaip.2025.11.030.
Peer-Reviewed Original Research
Relation of vertical ground reaction forces while walking to contralateral structural worsening in adults with unilateral knee osteoarthritis: the Multicenter Osteoarthritis Study
Corrigan P, Lewis C, Costello K, Kumar D, Felson D, Neogi T, Bacon K, LaValley M, Guermazi A, Roemer F, Nevitt M, Lewis C, Torner J, Stefanik J. Relation of vertical ground reaction forces while walking to contralateral structural worsening in adults with unilateral knee osteoarthritis: the Multicenter Osteoarthritis Study. Clinical Biomechanics 2025, 132: 106718. PMID: 41352273, DOI: 10.1016/j.clinbiomech.2025.106718.
Peer-Reviewed Original Research
Response to Letter to the Editor regarding ‘The relation of walking forces to structural damage in the knee: the Multicenter Osteoarthritis Study’
Sara L, Felson D, LaValley M, Stefanik J, Lewis C. Response to Letter to the Editor regarding ‘The relation of walking forces to structural damage in the knee: the Multicenter Osteoarthritis Study’. Osteoarthritis And Cartilage 2025 PMID: 41265825, DOI: 10.1016/j.joca.2025.11.006.
Peer-Reviewed Original Research
Sequential class switching generates antigen-specific gut IgA from IgG1 B cells
Siniscalco E, Meng H, Gabernet G, Pacheco G, Saghaei S, Ramirez S, Hills L, Faraji F, Chen S, Yin X, Dien C, Hoyt L, Liu E, Barrett A, Briggs N, Williams A, Shukla V, Crotty S, Wesemann D, Kleinstein S, Craft J, Eisenbarth S. Sequential class switching generates antigen-specific gut IgA from IgG1 B cells. Immunity 2025, 58: 3075-3093.e6. PMID: 41253159, DOI: 10.1016/j.immuni.2025.10.022.
Peer-Reviewed Original Research
This study investigates how gut-specific IgA antibodies are generated from IgG1 B cells through sequential class switching, highlighting a crucial mechanism for designing effective mucosal vaccines.
Full Summary
Imaging-Based Mortality Prediction in Patients with Systemic Sclerosis
Peltekian A, Senkow K, Durak G, Grudzinski K, Bemiss B, Dematte J, Richardson C, Markov N, Carns M, Aren K, Soriano A, Dapas M, Perlman H, Gundersheimer A, Selvan K, Varga J, Hinchcliff M, Warrior K, Gao C, Wunderink R, Budinger G, Choudhary A, Esposito A, Misharin A, Agrawal A, Bagci U. Imaging-Based Mortality Prediction in Patients with Systemic Sclerosis. Lecture Notes In Computer Science 2025, 16164: 14-23. DOI: 10.1007/978-3-032-07904-6_2.
Peer-Reviewed Original Research
Concepts
Minimalistic transcriptomic signatures permit accurate early prediction of COVID-19 mortality
Narendra R, Lydon E, Van Phan H, Spottiswoode N, Neyton L, Diray-Arce J, Network I, Consortium C, Consortium E, Becker P, Kim-Schulze S, Hoch A, Pickering H, van Zalm P, Cairns C, Altman M, Augustine A, Bosinger S, Eckalbar W, Guan L, Jayavelu N, Kleinstein S, Krammer F, Maecker H, Ozonoff A, Peters B, Rouphael N, Montgomery R, Reed E, Schaenman J, Steen H, Levy O, Haller S, Erle D, Hendrickson C, Krummel M, Matthay M, Woodruff P, Haddad E, Calfee C, Langelier C. Minimalistic transcriptomic signatures permit accurate early prediction of COVID-19 mortality. JCI Insight 2025, 10: e195436. PMID: 41212055, PMCID: PMC12643502, DOI: 10.1172/jci.insight.195436.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
The Last Night
Buckley L. The Last Night. JAMA: The Journal Of The American Medical Association 2025, 334: 2071-2072. PMID: 41196581, DOI: 10.1001/jama.2025.18916.
Peer-Reviewed Original Research
Concepts
VEXAS syndrome presenting with features of Sjögren’s disease: a case-based review of VEXAS and autoimmune disease overlap
Groener M, Baker H, Danve A. VEXAS syndrome presenting with features of Sjögren’s disease: a case-based review of VEXAS and autoimmune disease overlap. Clinical Rheumatology 2025, 1-8. PMID: 41193889, DOI: 10.1007/s10067-025-07773-6.
Peer-Reviewed Original Research
Concepts
Severe pincer morphology is associated with incident hip osteoarthritis: prospective individual participant data from 18 935 hips from the World COACH consortium
Riedstra N, Boel F, van Buuren M, Ahedi H, Arbabi V, Arden N, Baart S, Bierma-Zeinstra S, Cicutini F, Cootes T, Crossley K, Felson D, Gielis W, Heerey J, Jones G, Kluzek S, Lane N, Lindner C, Lynch J, van Meurs J, Mosler A, Nelson A, Nevitt M, Oei E, Runhaar J, Tang J, Weinans H, Agricola R. Severe pincer morphology is associated with incident hip osteoarthritis: prospective individual participant data from 18 935 hips from the World COACH consortium. British Journal Of Sports Medicine 2025, bjsports-2024-109595. PMID: 41192959, DOI: 10.1136/bjsports-2024-109595.
Peer-Reviewed Original Research
Gut-to-brain signaling restricts dietary protein intake during recovery from catabolic states
Jaschke N, Luchsinger J, Chen Z, Wulfmeyer V, de la Rosa X, Hahn O, Zhang C, Bachtel N, Cullen J, Rachner T, Medzhitov R, Rinschen M, Wu C, Wang A. Gut-to-brain signaling restricts dietary protein intake during recovery from catabolic states. Cell 2025, 188: 7481-7494.e16. PMID: 41192423, DOI: 10.1016/j.cell.2025.10.005.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Adverse Patellofemoral Morphology and Worsening Osteoarthritis: An Exploration of Composite vs. Single MRI Outcomes
McGinley B, LaValley M, Sieberer J, Fulkerson J, Lynch J, Guermazi A, Roemer F, Lewis C, Segal N, Felson D, Investigators F. Adverse Patellofemoral Morphology and Worsening Osteoarthritis: An Exploration of Composite vs. Single MRI Outcomes. Osteoarthritis Imaging 2025, 100383. DOI: 10.1016/j.ostima.2025.100383.
Peer-Reviewed Original Research
Enhanced antibody class switching and T cell responses to a self-amplifying RNA vs mRNA vaccine against SARS-CoV-2 spike protein 4547
Doherty E, Par-Young J, Osmani L, Filler R, Piecychna M, Abraham S, Jain N, Thambatti S, Nazaripour S, Thomas A, Leng L, Unutmaz D, Wilen C, Geall A, Kang I, Bucala R. Enhanced antibody class switching and T cell responses to a self-amplifying RNA vs mRNA vaccine against SARS-CoV-2 spike protein 4547. The Journal Of Immunology 2025, 214 DOI: 10.1093/jimmun/vkaf283.2218.
Peer-Reviewed Original Research

See All Publications