CPIRT Publications

• CFTR dictates monocyte adhesion by facilitating integrin clustering but not activation.Younis DA, Marosvari M, Liu W, Pulikkot S, Cao Z, Zhou B, Vella AT, McArdle S, Hu L, Chen Y, Gan W, Yu J, Bruscia EM, Fan Z. Proc Natl Acad Sci U S A. 2025 Jan 21; 2025 Jan 15. PMID: 39813254.
• Streptococcus pneumoniae Serotype Distribution Among US Adults Hospitalized With Community-Acquired Pneumonia, 2019-2020.Ramirez JA, Hubler RA, Ali M, Gray SL, Carrico R, McNaughton CD, Wunderink RG, Dela Cruz CS, Chilson EL, Cané AD, Isturiz RE, Pride MW, Jodar L, Gessner BD, Grant LR. Open Forum Infect Dis. 2025 Jan; 2024 Dec 17. PMID: 39758745.
• Exploring RSV transmission patterns in different age groups in the United States.Li K, Pitzer VE, Weinberger DM. medRxiv. 2024 Dec 26; 2024 Dec 26. PMID: 39763530.
• Tiled Amplicon Sequencing Enables Culture-free Whole-Genome Sequencing of Pathogenic Bacteria From Clinical Specimens.Kalinich CC, Gonzalez FL, Osmaston A, Breban MI, Distefano I, Leon C, Sheen P, Zimic M, Coronel J, Tan G, Crudu V, Ciobanu N, Codreanu A, Solano W, Ráez J, Allicock OM, Chaguza C, Wyllie AL, Brandt M, Weinberger DM, Sobkowiak B, Cohen T, Grandjean L, Grubaugh ND, Redmond SN. bioRxiv. 2024 Dec 20; 2024 Dec 20. PMID: 39763738.
• CRISPR-Cas9-based approaches for genetic analysis and epistatic interaction studies in Coxiella burnetii.Steiner S, Roy CR. mSphere. 2024 Dec 19; 2024 Nov 19. PMID: 39560384.
• Incorporating incubation period distributions to precisely estimate the association between rainfall and Legionella infection.Cassell K, Warren JL, Heneghen C, Weinberger DM. J Infect Dis. 2024 Dec 17; 2024 Dec 17. PMID: 39689015.
• Platelet-Monocyte Aggregate Instigates Inflammation and Vasculopathy in Kawasaki Disease.Zhang Y, Jia C, Guo M, Chen Q, Wen Y, Wang T, Xie Y, Fan X, Gao J, Yarovinsky TO, Liu R, Jiang Z, Wang M, Zhou J, Che D, Fu L, Edelson R, Gu X, Hwa J, Tang WH. Adv Sci (Weinh). 2024 Dec 12; 2024 Dec 12. PMID: 39665236.
• Postacute Sequelae of COVID-19 in Pediatric Patients Within the United States: A Scoping Review.Miller CM, Borre C, Green A, Funaro M, Oliveira CR, Iwasaki A. Am J Med Open. 2024 Dec; 2024 Sep 26. PMID: 39639960.
• SARS-CoV-2 reprograms murine alveolar macrophages to dampen flu.Tabachnikova A, Iwasaki A. Trends Immunol. 2024 Dec; 2024 Nov 22. PMID: 39580310.
• Prior knowledge-guided vision-transformer-based unsupervised domain adaptation for intubation prediction in lung disease at one week.Yang J, Henao JAG, Dvornek N, He J, Bower DV, Depotter A, Bajercius H, de Mortanges AP, You C, Gange C, Ledda RE, Silva M, Dela Cruz CS, Hautz W, Bonel HM, Reyes M, Staib LH, Poellinger A, Duncan JS. Comput Med Imaging Graph. 2024 Dec; 2024 Oct 15. PMID: 39515190.
• Ezrin drives adaptation of monocytes to the inflamed lung microenvironment.Gudneppanavar R, Di Pietro C, H Öz H, Zhang PX, Cheng EC, Huang PH, Tebaldi T, Biancon G, Halene S, Hoppe AD, Kim C, Gonzalez AL, Krause DS, Egan ME, Gupta N, Murray TS, Bruscia EM. Cell Death Dis. 2024 Nov 29; 2024 Nov 29. PMID: 39613751.
• Setdb1-loss induces type-I interferons and immune clearance of melanoma.McGeary MK, Damsky W, Daniels AJ, Lang SM, Xu Q, Song E, Huet-Calderwood C, Lou HJ, Paradkar S, Micevic G, Kaech SM, Calderwood DA, Turk BE, Yan Q, Iwasaki A, Bosenberg MW. Cancer Immunol Res. 2024 Nov 26; 2024 Nov 26. PMID: 39589394.
• CD74 promotes the formation of an immunosuppressive tumor microenvironment in triple-negative breast cancer in mice by inducing the expansion of tolerogenic dendritic cells and regulatory B cells.Pellegrino B, David K, Rabani S, Lampert B, Tran T, Doherty E, Piecychna M, Meza-Romero R, Leng L, Hershkovitz D, Vandenbark AA, Bucala R, Becker-Herman S, Shachar I. PLoS Biol. 2024 Nov; 2024 Nov 22. PMID: 39576827.
• Cotranslational molecular condensation of cochaperones and assembly factors facilitates axonemal dynein biogenesis.Li Y, Xu W, Cheng Y, Djenoune L, Zhuang C, Cox AL, Britto CJ, Yuan S, Wang S, Sun Z. Proc Natl Acad Sci U S A. 2024 Nov 19; 2024 Nov 14. PMID: 39541357.
• Chronic Viral Reactivation and Associated Host Immune Response and Clinical Outcomes in Acute COVID-19 and Post-Acute Sequelae of COVID-19.Maguire C, Chen J, Rouphael N, Pickering H, Phan HV, Glascock A, Chu V, Dandekar R, Corry D, Kheradmand F, Baden LR, Selaky R, McComsey GA, Haddad EK, Cairns CB, Pulendran B, Fernandez-Sesma A, Simon V, Metcalf JP, Higuita NIA, Messer WB, David MM, Nadeau KC, Kraft M, Bime C, Schaenman J, Erle D, Calfee CS, Atkinson MA, Brackenridge SC, Ehrlich LIR, Montgomery RR, Shaw AC, Hough CL, Geng LN, Hafler DA, Augustine AD, Becker PM, Peters B, Ozonoff A, Kim-Schulze SH, Krammer F, Bosinger S, Eckalbar W, Altman MC, Wilson M, Guan L, Kleinstein SH, Smolen KK, Reed EF, Levy O, Maecker H, Hunt P, Steen H, Diray-Arce J, Langelier CR, Melamed E. bioRxiv. 2024 Nov 16; 2024 Nov 16. PMID: 39605478.
• Relating in vivo RSV infection kinetics to host infectiousness in different age groups.Li K, Bont LJ, Weinberger DM, Pitzer VE. medRxiv. 2024 Nov 15; 2024 Nov 15. PMID: 39606407.
• Until it's done for everyone: the role of CFTR modulator label expansion.Britto CJ, Taylor-Cousar JL. Eur Respir J. 2024 Nov; 2024 Nov 14. PMID: 39542511.
• Plasma collagen neoepitopes are associated with multiorgan disease in the ACCESS and GRADS sarcoidosis cohorts.Sand JMB, Jessen H, Leeming DJ, Yu S, Lee CJ, Hu B, Sun Y, Adams T, Pivarnik T, Liu A, Woo S, McGovern JR, Fiorini V, Saber T, Higuero-Sevilla JP, Gulati M, Kaminski N, Damsky W, Shaw AC, Mohanty S, Goobie G, Zhang Y, Herzog EL, Ryu C. Thorax. 2024 Nov 14; 2024 Nov 14. PMID: 39117421.
• Does 23-Valent Pneumococcal Polysaccharide Vaccination Decrease All-Cause Mortality?Rezahosseini O, Eiberg MF, Weinberger DM, Harboe ZB. Open Forum Infect Dis. 2024 Nov; 2024 Nov 13. PMID: 39582506.
• Sex differences in postacute infection syndromes.Silva J, Iwasaki A. Sci Transl Med. 2024 Nov 13; 2024 Nov 13. PMID: 39536120.
• Persistent bloodstream infection in children: examining the role for repeat blood cultures.Puthawala CM, Feinn RS, Rivera-Viñas J, Lee H, Murray TS, Peaper DR. J Clin Microbiol. 2024 Nov 13; 2024 Oct 4. PMID: 39365070.
• InSeq analysis of defined Legionella pneumophila libraries identifies a transporter-encoding gene cluster important for intracellular replication in mammalian hosts.Moss CE, Roy CR. mBio. 2024 Nov 13; 2024 Oct 4. PMID: 39365064.
• A B cell screen against endogenous retroviruses identifies glycan-reactive IgM that recognizes a broad array of enveloped viruses.Yang Y, Treger RS, Hernandez-Bird J, Lu P, Mao T, Iwasaki A. Sci Immunol. 2024 Nov 8; 2024 Nov 8. PMID: 39514636.
• Particle size distribution of viable nebulized bacteriophage for the treatment of multi-drug resistant Pseudomonas aeruginosa.Thompson DL, Semersky Z, Feinn R, Huang P, Turner PE, Chan BK, Koff JL, Murray TS. Respir Med Res. 2024 Nov; 2024 Jul 25. PMID: 39121591.
• The protein disulfide isomerase A3 and osteopontin axis promotes influenza-induced lung remodelling.Kumar A, Mark ZF, Carbajal MP, DeLima DS, Chamberlain N, Walzer J, Ruban M, Chandrasekaran R, Daphtary N, Aliyeva M, Poynter ME, Janssen-Heininger YMW, Bates JH, Alcorn JF, Britto CJ, Dela Cruz CS, Jegga AG, Anathy V. Br J Pharmacol. 2024 Nov; 2024 Aug 8. PMID: 39118388.
• Interactions between respiratory syncytial virus and Streptococcus pneumoniae in the pathogenesis of childhood respiratory infections: a systematic review.Besteman SB, Bogaert D, Bont L, Mejias A, Ramilo O, Weinberger DM, Dagan R. Lancet Respir Med. 2024 Nov; 2024 Jul 8. PMID: 38991585.
• Two mosquito salivary antigens demonstrate promise as biomarkers of recent exposure to P. falciparum infected mosquito bites.Lapidus S, Goheen MM, Sy M, Deme AB, Ndiaye IM, Diedhiou Y, Mbaye AM, Hagadorn KA, Sene SD, Pouye MN, Thiam LG, Ba A, Guerra N, Mbengue A, Raduwan H, Gagnon J, Vigan-Womas I, Parikh S, Ko AI, Ndiaye D, Fikrig E, Chuang YM, Bei AK. J Infect Dis. 2024 Oct 30; 2024 Oct 30. PMID: 39475423.
• Estimated Population-Level Impact of Pneumococcal Conjugate Vaccines Against All-Cause Pneumonia Mortality Among Unvaccinated in 5 Latin American Countries.Prunas O, Shioda K, Toscano CM, Bastias M, Valenzuela-Bravo MT, Tito JD, Warren JL, Weinberger DM, de Oliveira LH. J Infect Dis. 2024 Oct 16. PMID: 38502711.
• Contact with young children is a major risk factor for pneumococcal colonization in older adults.Wyllie AL, Yolda-Carr D, Hislop MS, Mbodj S, Wurst L, Waghela P, Alexander-Parrish R, Grant LR, Arguedas A, Gessner BD, Weinberger DM. FEMS Microbes. 2024; 2024 Oct 14. PMID: 39502507.
• Thyroid Cancer Incidence During 2020 to 2021 COVID-19 Variant Waves.Bell R, Weinberger DM, Venkatesh M, Fernandes-Taylor S, Francis DO, Davies L. JAMA Otolaryngol Head Neck Surg. 2024 Oct 10; 2024 Oct 10. PMID: 39388144.
• CCR2+ monocytes are dispensable to resolve acute pulmonary Pseudomonas aeruginosa infections in WT and Cystic Fibrosis mice.Öz HH, Braga CL, Gudneppanavar R, Di Pietro C, Huang PH, Zhang PX, Krause DS, Egan ME, Murray TS, Bruscia EM. J Leukoc Biol. 2024 Oct 4; 2024 Oct 4. PMID: 39365279.
• Context-specific anti-inflammatory roles of type III interferon signaling in the lung in nonviral injuries.Feng J, Kim J, Wang VD, Chang D, Liu H, Bain WG, Robinson KM, Jie Z, Kotenko SV, Dela Cruz CS, Sharma L. Physiol Rep. 2024 Oct. PMID: 39455422.
• Estimated Deaths Averted in Adults by COVID-19 Vaccination in Select Latin American and Caribbean Countries.Savinkina A, Weinberger DM, Toscano CM, De Oliveira LH. Open Forum Infect Dis. 2024 Oct; 2024 Sep 10. PMID: 39411224.
• Eosinophilia Is a Favorable Marker for Pneumonia in Chronic Obstructive Pulmonary Disease.Gu KM, Jung JW, Kang MJ, Kim DK, Choi H, Cho YJ, Jang SH, Lee CH, Oh YM, Park JS, Kim JY. Tuberc Respir Dis (Seoul). 2024 Oct; 2024 May 3. PMID: 38710525.
• Disentangling the influence of reservoir abundance and pathogen shedding on zoonotic spillover of the Leptospira agent in urban informal settlements.Soni N, Eyre MT, Souza FN, Diggle PJ, Ko AI, Begon M, Pickup R, Childs JE, Khalil H, Carvalho-Pereira TSA, Pertile AC, Carvalho M, de Oliveira D, Nery N Jr, Giorgi E, Costa F. Front Public Health. 2024; 2024 Sep 18. PMID: 39360250.
• Genome-wide association study between SARS-CoV-2 single nucleotide polymorphisms and virus copies during infections.Li K, Chaguza C, Stamp J, Chew YT, Chen NFG, Ferguson D, Pandya S, Kerantzas N, Schulz W, Hahn AM, Ogbunugafor CB, Pitzer VE, Crawford L, Weinberger DM, Grubaugh ND. PLoS Comput Biol. 2024 Sep; 2024 Sep 17. PMID: 39288189.
• Real-World Effectiveness of Nirsevimab Against Respiratory Syncytial Virus: A Test-Negative Case-Control Study.Xu H, Aparicio C, Wats A, Araujo BL, Pitzer VE, Warren JL, Shapiro ED, Niccolai LM, Weinberger DM, Oliveira CR. medRxiv. 2024 Sep 12; 2024 Sep 12. PMID: 39314944.
• Hematological and biochemical profiles, infection and habitat quality in an urban rat population.Carvalho-Pereira T, Pedra GG, de Oliveira DS, Souza FN, Zeppelini CG, Santos LRN, Couto RD, Bahiense TC, da Silva EM, Begon M, Reis MG, Ko AI, Childs JE, Costa F. Res Sq. 2024 Sep 11; 2024 Sep 11. PMID: 39315279.
• A low-cost culture- and DNA extraction-free method for the molecular detection of pneumococcal carriage in saliva.Peno C, Lin T-Y, Hislop MS, Yolda-Carr D, Farjado K, York A, Pitzer VE, Weinberger DM, Bei AK, Allicock OM, Wyllie AL. Microbiol Spectr. 2024 Sep 3; 2024 Jul 19. PMID: 39028185.
• High burden of viruses and bacterial pathobionts drives heightened nasal innate immunity in children.Watkins TA, Green AB, Amat JAR, Cheemarla NR, Hänsel K, Lozano R, Dudgeon SN, Germain G, Landry ML, Schulz WL, Foxman EF. J Exp Med. 2024 Sep 2; 2024 Jul 1. PMID: 38949638.
• Pseudo-outbreak of Parengyodontium album related to contaminated saline used in specimen processing in the microbiology laboratory.Havill NL, Colandrea NA, Merwede J, Aniskiewicz MJ, Roberts SC, Patel K, Martinello RA, Peaper DR. Am J Infect Control. 2024 Sep; 2024 May 31. PMID: 38825239.
• Factors Associated with Long COVID Recovery among US Adults.Shah KM, Shah RM, Sawano M, Wu Y, Bishop P, Iwasaki A, Krumholz HM. Am J Med. 2024 Sep; 2024 Apr 21. PMID: 38649004.
• Bacterial cell surface characterization by phage display coupled to high-throughput sequencing.Grun CN, Jain R, Schniederberend M, Shoemaker CB, Nelson B, Kazmierczak BI. Nat Commun. 2024 Aug 29; 2024 Aug 29. PMID: 39209859.
• Severity-dependent test-seeking behaviors and test-negative designs: impact on estimated vaccine effectiveness and utility of analytic and design choices.Amin AB, Hitchings MDT, Ranzani OT, Andrews JR, Cummings DAT, Ko AI, Croda J, Dean NE. Am J Epidemiol. 2024 Aug 27; 2024 Aug 27. PMID: 39191656.
• Single-Cell Profiling Reveals Immune Aberrations in Progressive Idiopathic Pulmonary Fibrosis.Unterman A, Zhao AY, Neumark N, Schupp JC, Ahangari F, Cosme C Jr, Sharma P, Flint J, Stein Y, Ryu C, Ishikawa G, Sumida TS, Gomez JL, Herazo-Maya JD, Dela Cruz CS, Herzog EL, Kaminski N. Am J Respir Crit Care Med. 2024 Aug 15. PMID: 38717443.
• Damage sensing through TLR9 Regulates Inflammatory and Antiviral Responses During Influenza Infection.Kim J, Yuan Y, Agaronyan K, Zhao A, D Wang V, Gupta G, Essayas H, Kaminski A, McGovern J, Yu S, Woo S, Lee CJ, Gandhi S, Saber T, Saleh T, Hu B, Sun Y, Ishikawa G, Bain W, Evankovich J, Chen L, Yun H, Herzog EL, Dela Cruz CS, Ryu C, Sharma L. bioRxiv. 2024 Aug 12; 2024 Aug 12. PMID: 38496452.
• Macrophage migration inhibitory factor as a therapeutic target in neuro-oncology: A review.Jarmula J, Lee J, Lauko A, Rajappa P, Grabowski MM, Dhawan A, Chen P, Bucala R, Vogelbaum MA, Lathia JD. Neurooncol Adv. 2024 Jan-Dec; 2024 Aug 10. PMID: 39233830.
• Unraveling the Role of Viral Interference in Disrupting Biennial RSV Epidemics in Northern Stockholm.Li K, Hamrin J, Weinberger DM, Pitzer VE. medRxiv. 2024 Aug 9; 2024 Aug 9. PMID: 39148838.
• The human CD47 checkpoint is targeted by an immunosuppressive Aedes aegypti salivary factor to enhance arboviral skin infectivity.Marin-Lopez A, Huck JD, Esterly AT, Azcutia V, Rosen C, Garcia-Milian R, Sefik E, Vidal-Pedrola G, Raduwan H, Chen TY, Arora G, Halene S, Shaw AC, Palm NW, Flavell RA, Parkos CA, Thangamani S, Ring AM, Fikrig E. Sci Immunol. 2024 Aug 9; 2024 Aug 9. PMID: 39121194.
• Next generation triplex-forming PNAs for site-specific genome editing of the F508del CFTR mutation.Gupta A, Barone C, Quijano E, Piotrowski-Daspit AS, Perera JD, Riccardi A, Jamali H, Turchick A, Zao W, Saltzman WM, Glazer PM, Egan ME. J Cyst Fibros. 2024 Aug 5; 2024 Aug 5. PMID: 39107154.
• Long COVID science, research and policy.Al-Aly Z, Davis H, McCorkell L, Soares L, Wulf-Hanson S, Iwasaki A, Topol EJ. Nat Med. 2024 Aug; 2024 Aug 9. PMID: 39122965.
• SARS-CoV-2-related bat viruses evade human intrinsic immunity but lack efficient transmission capacity.Peña-Hernández MA, Alfajaro MM, Filler RB, Moriyama M, Keeler EL, Ranglin ZE, Kong Y, Mao T, Menasche BL, Mankowski MC, Zhao Z, Vogels CBF, Hahn AM, Kalinich CC, Zhang S, Huston N, Wan H, Araujo-Tavares R, Lindenbach BD, Homer R, Pyle AM, Martinez DR, Grubaugh ND, Israelow B, Iwasaki A, Wilen CB. Nat Microbiol. 2024 Aug; 2024 Jul 29. PMID: 39075235.
• Atypical pneumonia testing in transplant recipients.Feller F, Trubin P, Malinis M, Vogel JS, Merwede J, Peaper DR, Azar MM. Transpl Infect Dis. 2024 Aug; 2024 Mar 2. PMID: 38430482.
• Internal Tremors and Vibrations in Long COVID: A Cross-Sectional Study.Zhou T, Sawano M, Arun AS, Caraballo C, Michelsen T, McAlpine LS, Bhattacharjee B, Lu Y, Khera R, Huang C, Warner F, Herrin J, Iwasaki A, Krumholz HM. Am J Med. 2024 Jul 26; 2024 Jul 26. PMID: 39069199.
• Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma.Valdez CN, Sánchez-Zuno GA, Osmani L, Ibrahim W, Galan A, Bacchiocchi A, Halaban R, Kulkarni RP, Kang I, Bucala R, Tran T. Oncotarget. 2024 Jul 19; 2024 Jul 19. PMID: 39028303.
• Participant Diversity in United States Randomized Controlled Trials of Antibacterials for Staphylococcus aureus Infections, 2000-2021.Kwon J, Pelletiers W, Galloway Peña J, van Duin D, Ledbetter L, Baum K, Ruffin F, Knisely JM, Bizzell E, Fowler VG Jr, Chambers HF, Pettigrew MM. Clin Infect Dis. 2024 Jul 19. PMID: 38306502.
• Downregulation of adipose LPL by PAR2 contributes to the development of hypertriglyceridemia.Huang Y, Chen L, Li L, Qi Y, Tong H, Wu H, Xu J, Leng L, Cheema S, Sun G, Xia Z, McGuire J, Rodrigues B, Young LH, Bucala R, Qi D. JCI Insight. 2024 Jul 8; 2024 Jul 8. PMID: 38973609.
• A small-molecule allele-selective transcriptional inhibitor of the MIF immune susceptibility locus.Li J, Leng L, Pantouris G, Manjula R, Piecychna M, Abriola L, Hu B, Lolis E, Armstrong ME, Donnelly SC, Bucala R. J Biol Chem. 2024 Jul; 2024 Jun 3. PMID: 38838773.
• Global patterns of rebound to normal RSV dynamics following COVID-19 suppression.Thindwa D, Li K, Cooper-Wootton D, Zheng Z, Pitzer VE, Weinberger DM. BMC Infect Dis. 2024 Jun 25; 2024 Jun 25. PMID: 38918718.
• Human antibodies in Mexico and Brazil neutralizing tick-borne flaviviruses.Cervantes Rincón T, Kapoor T, Keeffe JR, Simonelli L, Hoffmann HH, Agudelo M, Jurado A, Peace A, Lee YE, Gazumyan A, Guidetti F, Cantergiani J, Cena B, Bianchini F, Tamagnini E, Moro SG, Svoboda P, Costa F, Reis MG, Ko AI, Fallon BA, Avila-Rios S, Reyes-Téran G, Rice CM, Nussenzweig MC, Bjorkman PJ, Ruzek D, Varani L, MacDonald MR, Robbiani DF. Cell Rep. 2024 Jun 25; 2024 May 29. PMID: 38819991.
• A causal link between autoantibodies and neurological symptoms in long COVID.Santos Guedes de Sa K, Silva J, Bayarri-Olmos R, Brinda R, Alec Rath Constable R, Colom Diaz PA, Kwon DI, Rodrigues G, Wenxue L, Baker C, Bhattacharjee B, Wood J, Tabacof L, Liu Y, Putrino D, Horvath TL, Iwasaki A. medRxiv. 2024 Jun 19; 2024 Jun 19. PMID: 38947091.
• Inflammatory Response and Defects on Myelin Integrity in the Olfactory System of K18hACE2 Mice Infected with SARS-CoV-2.Martin-Lopez E, Brennan B, Mao T, Spence N, Meller SJ, Han K, Yahiaoui N, Wang C, Iwasaki A, Greer CA. eNeuro. 2024 Jun; 2024 Jun 17. PMID: 38834299.
• Potential Impact of Higher-Valency Pneumococcal Conjugate Vaccines Among Adults in Different Localities in Germany.Ellingson MK, Weinberger DM, van der Linden M, Perniciaro S. J Infect Dis. 2024 Jun 14. PMID: 38059558.
• Phage Therapy for Respiratory Infections: Opportunities and Challenges.Khosravi A, Chen Q, Echterhof A, Koff JL, Bollyky PL. Lung. 2024 Jun; 2024 May 21. PMID: 38772946.
• Effectiveness of the fourth dose of COVID-19 vaccines against severe COVID-19 among adults 40 years or older in Brazil: a population-based cohort study.Lazar Neto F, Hitchings MDT, Amin AB, de França GVA, Lind ML, Scaramuzzini Torres MS, Tsuha DH, de Oliveira RD, Cummings DAT, Dean NE, Andrews JR, Ko AI, Croda J, Ranzani OT. Lancet Reg Health Am. 2024 Jun; 2024 May 3. PMID: 38737773.
• "Rounding Third Base and Heading Home": Arthritis & Rheumatology in 2024.Solomon DH, Kaplan MJ, Nigrovic PA, Bucala R. Arthritis Rheumatol. 2024 Jun; 2024 Apr 4. PMID: 38572586.
• Factors Associated With Long COVID: Insights From Two Nationwide Surveys.Wu Y, Sawano M, Wu Y, Shah RM, Bishop P, Iwasaki A, Krumholz HM. Am J Med. 2024 Jun; 2024 Mar 14. PMID: 38490304.
• Macrophage-derived macrophage migration inhibitory factor mediates renal injury in anti-glomerular basement membrane glomerulonephritis.Yang H, Li J, Huang XR, Bucala R, Xu A, Lan HY. Front Immunol. 2024; 2024 May 23. PMID: 38846956.
• Is it time to reduce the length of postgraduate training for physician-scientists in internal medicine?Gallagher EJ, Conlin PR, Kazmierczak BI, Vyas JM, Ajijola OA, Kontos CD, Baiocchi RA, Rhee KY, Hu PJ, Isales CM, Williams CS, Rockey DC. JCI Insight. 2024 May 22; 2024 May 22. PMID: 38775155.
• Enhancing in vivo cell and tissue targeting by modulation of polymer nanoparticles and macrophage decoys.Piotrowski-Daspit AS, Bracaglia LG, Eaton DA, Richfield O, Binns TC, Albert C, Gould J, Mortlock RD, Egan ME, Pober JS, Saltzman WM. Nat Commun. 2024 May 18; 2024 May 18. PMID: 38762483.
• The PAX LC Trial: A Decentralized, Phase 2, Randomized, Double-Blind Study of Nirmatrelvir/Ritonavir Compared with Placebo/Ritonavir for Long COVID.Krumholz HM, Sawano M, Bhattacharjee B, Caraballo C, Khera R, Li SX, Herrin J, Coppi A, Holub J, Henriquez Y, Johnson MA, Goddard TB, Rocco E, Hummel AC, Al Mouslmani M, Putrino DF, Carr KD, Carvajal-Gonzalez S, Charnas L, De Jesus M, Ziegler FW 3rd, Iwasaki A. Am J Med. 2024 May 10; 2024 May 10. PMID: 38735354.
• Performance of two modified two-tier algorithms for the serologic diagnosis of Lyme disease.Landry ML, Hassan S, Rottmann BG, Pesak SJ, Ordazzo M, Skrzyniarz M, Deponte S, Peaper DR. J Clin Microbiol. 2024 May 8; 2024 Apr 10. PMID: 38597655.
• Beyond antiviral: role of IFN-I in brain development.Baker CA, Iwasaki A. Trends Immunol. 2024 May; 2024 Apr 20. PMID: 38644134.
• IL-1 receptor 1 signaling shapes the development of viral antigen-specific CD4(+) T cell responses following COVID-19 mRNA vaccination.Park HJ, Shin MS, Shin JJ, Kim H, Kang B, Par-Young J, Unlu S, Afinogenova Y, Catanzaro J, Young J, Kim M, Lee SJ, Jeon S, You S, Racke MK, Bucala R, Kang I. EBioMedicine. 2024 May; 2024 Apr 18. PMID: 38640835.
• Randomized Phase II Trial of Imiquimod with or without 9-Valent HPV Vaccine versus Observation in Patients with High-grade Pre-neoplastic Cervical Lesions (NCT02864147).Sheth SS, Oh JE, Bellone S, Siegel ER, Greenman M, Mutlu L, McNamara B, Pathy S, Clark M, Azodi M, Altwerger G, Andikyan V, Huang G, Ratner E, Kim DJ, Iwasaki A, Levi AW, Buza N, Hui P, Flaherty S, Schwartz PE, Santin AD. Clin Cancer Res. 2024 May 1. PMID: 38592381.
• Anti-inflammatory roles of type I interferon signaling in the lung.Feng J, Liu Y, Kim J, Ahangari F, Kaminski N, Bain WG, Jie Z, Dela Cruz CS, Sharma L. Am J Physiol Lung Cell Mol Physiol. 2024 May 1; 2024 Feb 20. PMID: 38375579.
• Developmental changes in lung function of mice are independent of sex as a biological variable.Bärnthaler T, Ramachandra AB, Ebanks S, Guerrera N, Sharma L, Dela Cruz CS, Humphrey JD, Manning EP. Am J Physiol Lung Cell Mol Physiol. 2024 May 1; 2024 Feb 20. PMID: 38375577.
• The full value of immunisation against respiratory syncytial virus for infants younger than 1 year: effects beyond prevention of acute respiratory illness.Feikin DR, Karron RA, Saha SK, Sparrow E, Srikantiah P, Weinberger DM, Zar HJ. Lancet Infect Dis. 2024 May; 2023 Nov 21. PMID: 38000374.
• Gender differences in the perception of leptospirosis severity, behaviours, and Leptospira exposure risk in urban Brazil: a cross-sectional study.Delight EA, de Carvalho Santiago DC, Palma FAG, de Oliveira D, Souza FN, Santana JO, Hidano A, López YAA, Reis MGG, Ko AI, Marphatia AA, Cremonense C, Costa F, Eyre MT. medRxiv. 2024 Apr 30; 2024 Apr 30. PMID: 38746452.
• Intranasal neomycin evokes broad-spectrum antiviral immunity in the upper respiratory tract.Mao T, Kim J, Peña-Hernández MA, Valle G, Moriyama M, Luyten S, Ott IM, Gomez-Calvo ML, Gehlhausen JR, Baker E, Israelow B, Slade M, Sharma L, Liu W, Ryu C, Korde A, Lee CJ, Silva Monteiro V, Lucas C, Dong H, Yang Y, Gopinath S, Wilen CB, Palm N, Dela Cruz CS, Iwasaki A. Proc Natl Acad Sci U S A. 2024 Apr 30; 2024 Apr 22. PMID: 38648490.
• Macrophage Migration Inhibitory Factor (MIF) and D-Dopachrome Tautomerase (DDT): Pathways to Tumorigenesis and Therapeutic Opportunities.Valdez CN, Sánchez-Zuno GA, Bucala R, Tran TT. Int J Mol Sci. 2024 Apr 29; 2024 Apr 29. PMID: 38732068.
• Exploring new perspectives in immunology.Medzhitov R, Iwasaki A. Cell. 2024 Apr 25. PMID: 38670066.
• Long COVID Characteristics and Experience: A Descriptive Study From the Yale LISTEN Research Cohort.Sawano M, Wu Y, Shah RM, Zhou T, Arun AS, Khosla P, Kaleem S, Vashist A, Bhattacharjee B, Ding Q, Lu Y, Caraballo C, Warner F, Huang C, Herrin J, Putrino D, Michelsen T, Fisher L, Adinig C, Iwasaki A, Krumholz HM. Am J Med. 2024 Apr 24; 2024 Apr 24. PMID: 38663793.
• Lytic bacteriophages induce the secretion of antiviral and proinflammatory cytokines from human respiratory epithelial cells.Zamora PF, Reidy TG, Armbruster CR, Sun M, Van Tyne D, Turner PE, Koff JL, Bomberger JM. PLoS Biol. 2024 Apr; 2024 Apr 23. PMID: 38652717.
• Two mosquito salivary antigens demonstrate promise as biomarkers of recent exposure to P. falciparum infected mosquito bites.Lapidus S, Goheen MM, Sy M, Deme AB, Ndiaye IM, Diedhiou Y, Mbaye AM, Hagadorn KA, Sene SD, Pouye MN, Thiam LG, Ba A, Guerra N, Mbengue A, Raduwan H, Vigan-Womas I, Parikh S, Ko AI, Ndiaye D, Fikrig E, Chuang YM, Bei AK. medRxiv. 2024 Apr 22; 2024 Apr 22. PMID: 38712295.
• MIF-Modulated Spinal Proteins Associated with Persistent Bladder Pain: A Proteomics Study.Ye S, Agalave NM, Ma F, Mahmood DFD, Al-Grety A, Khoonsari PE, Leng L, Svensson CI, Bucala R, Kultima K, Vera PL. Int J Mol Sci. 2024 Apr 19; 2024 Apr 19. PMID: 38674069.
• Cohort study of patients with advanced cancer: outcomes associated with duration of antibiotic therapy for non-ventilator hospital-acquired pneumonia.Lee S, Benson J, Cohen A, Quagliarello V, Juthani-Mehta M, Datta R. Antimicrob Steward Healthc Epidemiol. 2024; 2024 Apr 18. PMID: 38655023.
• Corrigendum to "Extensive transmission of SARS-CoV-2 BQ.1* variant in a population with high levels of hybrid immunity: A prevalence survey" [International Journal of Infectious Diseases 139 (2024) 159-167].Aguilar Ticona JP, Xiao M, Li D, Nery JN, Hitchings M, Andrade Belitardo EMM, Fofana MO, Victoriano R, Cruz JS, de Moraes L, Strobel IM, Silva JJ, Sena do Aragão Filho A, Ribeiro GS, Reis MG, Costa F, Khouri R, Ko AI, Cummings DAT. Int J Infect Dis. 2024 Apr; 2024 Mar 6. PMID: 38452689.
• Compartmentalized ocular lymphatic system mediates eye-brain immunity.Yin X, Zhang S, Lee JH, Dong H, Mourgkos G, Terwilliger G, Kraus A, Geraldo LH, Poulet M, Fischer S, Zhou T, Mohammed FS, Zhou J, Wang Y, Malloy S, Rohner N, Sharma L, Salinas I, Eichmann A, Thomas JL, Saltzman WM, Huttner A, Zeiss C, Ring A, Iwasaki A, Song E. Nature. 2024 Apr; 2024 Feb 28. PMID: 38418880.
• A small molecule macrophage migration inhibitory factor agonist ameliorates age-related myocardial intolerance to ischemia-reperfusion insults via metabolic regulation.Wang H, Slotabec L, Didik S, Li Z, Leng L, Zhao B, Bucala R, Li J. Metabolism. 2024 Apr; 2024 Jan 15. PMID: 38232801.
• Human iPSC-Based Model of COPD to Investigate Disease Mechanisms, Predict SARS-COV-2 Outcome, and Test Preventive Immunotherapy.Dagher R, Moldobaeva A, Gubbins E, Clark S, Madel Alfajaro M, Wilen CB, Hawkins F, Qu X, Chien Chiang C, Li Y, Clarke L, Ikeda Y, Brown C, Kolbeck R, Ma Q, Rojas M, Koff JL, Ghaedi M. Stem Cells. 2024 Mar 14. PMID: 38183264.
• Proceedings of the Clinical Microbiology Open 2022-assessing clinical laboratory and industry responses to COVID-19 pandemic testing capacity challenges (part 1).Peaper DR, Doern CD, Sharp S. J Clin Microbiol. 2024 Mar 13; 2024 Feb 20. PMID: 38379142.
• Interventions to support fellowship application success among predoctoral physician-scientists.Fitzsimonds RM, Gorelick FS, Kazmierczak BI. JCI Insight. 2024 Mar 8; 2024 Mar 8. PMID: 38456505.
• Overestimation of Severe Acute Respiratory Syndrome Coronavirus 2 Household Transmission in Settings of High Community Transmission: Insights From an Informal Settlement Community in Salvador, Brazil.Aguilar Ticona JP, Nery N Jr, Hitchings M, Belitardo EMMA, Fofana MO, Dorión M, Victoriano R, Cruz JS, Oliveira Santana J, de Moraes LEP, Cardoso CW, Ribeiro GS, Reis MG, Khouri R, Costa F, Ko AI, Cummings DAT. Open Forum Infect Dis. 2024 Mar; 2024 Feb 5. PMID: 38516384.
• Hypertension Control During the Coronavirus Disease 2019 Pandemic: A Cohort Study Among US Veterans.Korves C, Peixoto AJ, Lucas BP, Davies L, Weinberger DM, Rentsch C, Vashi A, Young-Xu Y, King J Jr, Asch SM, Justice AC. Med Care. 2024 Mar 1; 2024 Jan 17. PMID: 38284412.
• Novel Approaches to Multidrug-Resistant Infections in Cystic Fibrosis.Murray TS, Stanley G, Koff JL. Infect Dis Clin North Am. 2024 Mar. PMID: 38280761.
• Incorporating Efficacy Data from Initial Trials Into Subsequent Evaluations: Application to Vaccines Against Respiratory Syncytial Virus.Warren JL, Sundaram M, Pitzer VE, Omer SB, Weinberger DM. Epidemiology. 2024 Mar 1; 2023 Nov 14. PMID: 37963353.
• The Emerging Spectrum of Somatic Mutation in Rheumatic Disease: Clonal Hematopoiesis Connects Aging With Giant Cell Arteritis.Bucala R, Tsao BP. Arthritis Rheumatol. 2024 Mar; 2024 Jan 3. PMID: 37961826.
• The role of viral interference in shaping RSV epidemics following the 2009 H1N1 influenza pandemic.Li K, Thindwa D, Weinberger DM, Pitzer VE. medRxiv. 2024 Feb 27; 2024 Feb 27. PMID: 38464193.
• Aberrant immune programming in neutrophils in cystic fibrosis.Hu Y, Bojanowski CM, Britto CJ, Wellems D, Song K, Scull C, Jennings S, Li J, Kolls JK, Wang G. J Leukoc Biol. 2024 Feb 23. PMID: 37939820.