2008
A systematic review and meta-analysis of randomized, controlled trials of moderate sedation for routine endoscopic procedures
McQuaid KR, Laine L. A systematic review and meta-analysis of randomized, controlled trials of moderate sedation for routine endoscopic procedures. Gastrointestinal Endoscopy 2008, 67: 910-923. PMID: 18440381, DOI: 10.1016/j.gie.2007.12.046.Peer-Reviewed Original ResearchConceptsModerate sedationPatient satisfactionAdverse eventsPhysician assessmentSystematic reviewSedation-related complicationsSerious adverse eventsPoor methodologic qualitySuperior patient satisfactionRoutine endoscopic proceduresComputerized bibliographic databasesActive regimenActive regimensLonger sedationRandomized trialsPatient assessmentMethodologic qualityAvailable agentsProcedure timeEndoscopic proceduresLower riskSedationMidazolamRegimensPropofol
2001
Therapy for Helicobacter pylori in patients with nonulcer dyspepsia. A meta-analysis of randomized, controlled trials.
Laine L, Schoenfeld P, Fennerty M. Therapy for Helicobacter pylori in patients with nonulcer dyspepsia. A meta-analysis of randomized, controlled trials. Annals Of Internal Medicine 2001, 134: 361-9. PMID: 11242496, DOI: 10.7326/0003-4819-134-5-200103060-00008.Peer-Reviewed Original ResearchConceptsH. pylori eradication therapyNonulcer dyspepsiaPylori eradication therapyEradication therapyControl therapyOdds ratioH. pyloriHelicobacter pyloriDefinition of dyspepsiaDuplicate data extractionEnd of therapyH. pylori infectionAnalysis of trialsPylori infectionCombination therapyMethodologic qualityTreatment successDyspepsiaPersistent infectionReference listsTherapyPatientsStudy designPrimary investigatorPylori
1995
Endoscopic ligation compared with sclerotherapy for treatment of esophageal variceal bleeding. A meta-analysis.
Laine L, Cook D. Endoscopic ligation compared with sclerotherapy for treatment of esophageal variceal bleeding. A meta-analysis. Annals Of Internal Medicine 1995, 123: 280-7. PMID: 7611595, DOI: 10.7326/0003-4819-123-4-199508150-00007.Peer-Reviewed Original ResearchConceptsEsophageal variceal bleedingTreatment of patientsEndoscopic ligationVariceal bleedingEsophageal varicesEndoscopic treatmentDuplicate data abstractionDuplicate independent reviewEndoscopic treatment sessionsRate of deathRelevant primary articlesReview of citationsVariceal obliterationBacterial peritonitisLigation therapyPulmonary infectionEsophageal strictureMethodologic qualitySclerotherapyMortality rateTreatment sessionsPatientsRelevant articlesPrimary investigatorUnpublished studies