1993
Effect of ursodeoxycholic acid on intracellular pH regulation in isolated rat bile duct epithelial cells
Alvaro D, Mennone A, Boyer J. Effect of ursodeoxycholic acid on intracellular pH regulation in isolated rat bile duct epithelial cells. American Journal Of Physiology 1993, 265: g783-g791. PMID: 8238362, DOI: 10.1152/ajpgi.1993.265.4.g783.Peer-Reviewed Original ResearchConceptsBile duct epithelial cellsUrsodeoxycholic acidDuct epithelial cellsBDE cellsHCO3- excretionEffect of UDCAEpithelial cellsHCO3- exchangeCholic acidKrebs-Ringer bicarbonateUDCA infusionUDCA withdrawalRat bile duct epithelial cellsKRB mediumHCO3- symportNormal rat liverIntracellular pH regulationHCO3- secretionSodium tauroursodeoxycholateSecondary activationBasal levelsPresence of HCO3TauroursodeoxycholateRat liverHypercholeresis
1987
Ursodeoxycholate stimulates Na+-H+ exchange in rat liver basolateral plasma membrane vesicles.
Moseley R, Ballatori N, Smith D, Boyer J. Ursodeoxycholate stimulates Na+-H+ exchange in rat liver basolateral plasma membrane vesicles. Journal Of Clinical Investigation 1987, 80: 684-690. PMID: 3040805, PMCID: PMC442291, DOI: 10.1172/jci113122.Peer-Reviewed Original Research