1996
Tauroursodeoxycholic acid activates protein kinase C in isolated rat hepatocytes
Beuers U, Throckmorton D, Anderson, Isales C, Thasler W, Kullak-Ublick G, Sauter G, Koebe H, Paumgartner G, Boyer J. Tauroursodeoxycholic acid activates protein kinase C in isolated rat hepatocytes. Gastroenterology 1996, 110: 1553-1563. PMID: 8613063, DOI: 10.1053/gast.1996.v110.pm8613063.Peer-Reviewed Original ResearchConceptsEffect of TUDCATauroursodeoxycholic acidProtein kinase CHepatocellular Ca2Chronic cholestatic liver diseaseCholestatic liver diseaseAlpha-PKCPKC activityLiver diseaseLiver functionRadioenzymatic techniqueExperimental cholestasisPhorbol ester phorbolActivation of PKCKinase CTaurocholic acidImmunofluorescence techniqueAbstractTextMembrane-associated PKC activitySignificant increaseAIMSStimulation of exocytosisUnknown mechanismParticulate membrane fractionHepatocytes
1987
The excretion pattern of biliverdin and bilirubin in bile of the small skate (Raja erinacea)
Grossbard M, Boyer J, Gordon E. The excretion pattern of biliverdin and bilirubin in bile of the small skate (Raja erinacea). Journal Of Comparative Physiology B 1987, 157: 61-66. PMID: 3571566, DOI: 10.1007/bf00702729.Peer-Reviewed Original ResearchConceptsIntravenous administrationHepatic bileGallbladder volumeBile pigment compositionBiliary excretionGallbladder bileExcretion patternsBilirubin conjugatesUnconjugated bilirubinBileBilirubinBilirubin diglucuronideBilirubin monoglucuronideSignificant increaseAdministrationSmall skateBiliverdinDay period