YSPH Environmental Health Sciences Imaging Mass Spectrometry and Omics Symposium
Modern mass spectrometry imaging technologies permits high-resolution spatial localization of metabolites,
proteins and drugs within intact tissue sections, single cells and many other biological surfaces. It holds significant
promise in augmenting the spatial fidelity of classical histology by generating highly robust big data about the
metabolic, lipidomic and proteomic content of samples. A single MSI experiment produces tissue images of hundreds
to thousands of molecular species. With the use of machine learning technologies, it is possible to determine the
molecules that correlate with tissue pathology, cell type, drug distribution and/or toxicity. MSI technologies have a
particular translational relevance to cancer research where molecules and pathways can be characterized in tumor
cells and their microenvironment, allowing direct therapeutic effects to be assessed. Please join the Yale School of
Public Health for this symposium, that will explore advances and challenges in analytical and computational tissue
imaging mass spectrometry.
Speakers
Vanderbilt University School of Medicine
Richard A. Caprioli, PhDProfessor of Biochemistry, Chemistry, Medicine, Pharmacology, BiochemistryColumbia University
Presha Rajbhandari, PhDPostdoctoral Research ScientistMD Anderson Cancer Center
Erik N.K. Creesman, MD, PhD, FSIRAssistant Professor of Interventional RadiologyAgios Pharmaceuticals
Thomas Roddy, PhDSr. Director of MetabolismWaters Corporation
Stephen MartinVP ResearchImperial College London
Dr. Kirill VeselkovFaculty of MedicineUniversity of Michigan
Lana Garmire, PhDAssociate Professor, Computational Medicine and Bioinformatics