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Brian Richard Smith, MD

Professor of Laboratory Medicine, of Biomedical Engineering, of Medicine (Hematology) and of Pediatrics
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Additional Titles

Deputy Dean for Research, (Clinical and Translational)

Director, Clinical Immunology Laboratory, Laboratory Medicine

Chair, Laboratory Medicine

Chief, Laboratory Medicine, Yale New Haven Hospital

Contact Info

Yale School of Medicine

333 Cedar Street, SHM L-206, P.O. Box 208055

New Haven, CT 06520-8055

United States

About

Titles

Professor of Laboratory Medicine, of Biomedical Engineering, of Medicine (Hematology) and of Pediatrics

Deputy Dean for Research, (Clinical and Translational); Director, Clinical Immunology Laboratory, Laboratory Medicine; Chair, Laboratory Medicine

Positions outside Yale

Chief, Laboratory Medicine, Yale New Haven Hospital

Biography

Brian R. Smith MD is Deputy Dean for Clinical and Translational Research at the Yale School of Medicine, as well as Co-Director of the Yale Center for Clinical Investigation (Co-PI of Yale's CTSA Award), Chair of the Department of Laboratory Medicine and Professor of Laboratory Medicine, Biomedical Engineering, Internal Medicine and Pediatrics at Yale University. He is the Chief of Laboratory Medicine and Attending Physician at Yale New Haven Hospital and also an attending physician at the Connecticut VA Medical Center and the Bridgeport Hospital.

Dr. Smith received his undergraduate degree summa cum laude from Princeton University, his medical degree from the Harvard Medical School, and his residency/fellowship training at The Brigham & Women’s Hospital, Boston Children’s Hospital, and Dana Farber Cancer Center. He is board certified in Pathology / Hematopathology and in Internal Medicine / Hematology-Oncology. In addition to his clinical work, Dr. Smith has an investigative interest in the inflammation-hemostasis interface, especially in relation to biomaterials, as well as in cellular immunotherapeutics, with over 175 publications. His work extends from basic wet bench research through clinical and epidemiological trials (T1-T4). He has been continuously funded by the NIH at the PI-level for over 35 years.

In these various roles, Dr. Smith has major administrative responsibility for the School’s research enterprise across the T1-T4 spectrum, as well as educational responsibilities across the scientific pipeline from STEM high school student programs through undergraduate, graduate, and post-graduate training, for MDs, PhDs, and MD/PhDs. He is the initiator and long-standing PI of Laboratory Medicine’s post-doctoral T32 training program in Immunohematology and has personally mentored over 50 MD, MD/PhD, and PhD trainees, most of whom hold tenure-track positions at major research universities. In addition to directing trainees in bench and translational research, Dr. Smith has extensive experience in the didactic aspects of comprehensive training and career development for clinician-scientists, having developed and published curricula in Laboratory Medicine, developed and published new physician-scientist training paradigms in his field, and, in his capacity as the Chair of the Research Committee for the Association of Pathology Chairs, initiated and helped negotiate a dialogue with the American Board of Pathology that, with the work of many other Chairs of Pathology and Laboratory Medicine, resulted in the adoption of a specific Physician-Scientist residency pathway by the Board. Similarly, through his research experience, dean position, and appointment in the Graduate School of Arts and Sciences, he is very involved with all aspects of PhD training at both the pre- and post-doctoral levels. He has been an invited lecturer on Bioethics and previously served on the NIH Recombinant DNA Advisory Committee. Dr. Smith has also played a significant role in gender equity initiatives at Yale. In addition, he has overseen the implementation of research core facilities in Translational Immune Monitoring, Flow Cytometry, and Clinical Sample Real Time Acquisition, chairs the Clinical Research Technology Committee, and has been a guiding member of a Cellular Therapy core resource, all of which have been used successfully by Yale investigators as well as by investigators from other universities.

Appointments

Other Departments & Organizations

Education & Training

Fellow
Brigham & Women's Hospital/Dana Farber Cancer Center/Children's Hospital,Boston (1982)
Resident
Brigham & Women's Hospital/Harvard Medical School (1978)
MD
Harvard University (1976)
BA
Princeton University, Chemistry (1972)

Research

Overview

Medical Subject Headings (MeSH)

Biomedical Engineering; Blood; Blood Cells; Bone Marrow Cells; Curriculum; Diagnostic Techniques and Procedures; Disease Management; Education, Professional; Ethics; Hematology; Hematopoietic System; Hemic and Lymphatic Diseases; Immune System; Laboratories; Lymphoid Tissue; Medical Laboratory Science; Point-of-Care Systems; Practice Patterns, Physicians'; Religion and Medicine; Religion and Science; Stem Cells; Students; Students, Medical; Teaching

Research at a Glance

Yale Co-Authors

Frequent collaborators of Brian Richard Smith's published research.

Publications

2020

2019

2018

2016

2015

2014

Clinical Trials

Current Trials

Academic Achievements & Community Involvement

  • honor

    Evans Award for Outstanding Contributions to Laboratory Medicine

  • honor

    Chair (elected), Research Committee and Member of the Council

  • honor

    President, Academy of Clinical Laboratory Physicians & Scientists

Clinical Care

Overview

Clinical Specialties

Laboratory Medicine; Hematopathology; Hematology & Oncology; Internal Medicine

Fact Sheets

Board Certifications

  • Hematology (Pathology)

    Certification Organization
    AB of Pathology
    Original Certification Date
    1999
  • Medical Oncology

    Certification Organization
    AB of Internal Medicine
    Original Certification Date
    1981
  • Hematology (Internal Medicine)

    Certification Organization
    AB of Internal Medicine
    Original Certification Date
    1980
  • Internal Medicine

    Certification Organization
    AB of Internal Medicine
    Original Certification Date
    1979

Yale Medicine News

Get In Touch

Contacts

Academic Office Number
Secondary Academic Office Number
Appointment Number
Office Fax Number
Mailing Address

Yale School of Medicine

333 Cedar Street, SHM L-206, P.O. Box 208055

New Haven, CT 06520-8055

United States

Administrative Support

Locations

  • Deputy Dean Office

    Academic Office

    Clinic Building

    789 Howard Avenue, Wing SHM L206

    New Haven, CT 06519

    Dean's Office

    203.737.5271
  • Patient Care Locations

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