2017
Nonalcoholic Fatty Liver Disease as a Nexus of Metabolic and Hepatic Diseases
Samuel VT, Shulman GI. Nonalcoholic Fatty Liver Disease as a Nexus of Metabolic and Hepatic Diseases. Cell Metabolism 2017, 27: 22-41. PMID: 28867301, PMCID: PMC5762395, DOI: 10.1016/j.cmet.2017.08.002.Peer-Reviewed Original ResearchConceptsInsulin resistanceNonalcoholic fatty liver diseaseFatty liver diseasePeripheral insulin resistanceHepatic insulin resistanceNew pharmacological strategiesHepatic complicationsBariatric surgeryLiver diseaseInsulin-stimulated glycogen synthesisHepatic diseasePharmacological strategiesNAFLDReceptor activationHepatic glucoseLipid metabolismInsulin receptor activationWeight lossEnergy expenditureHepatic diacylglycerolsGlycogen synthesisDiseaseLipid synthesisFlux of substratesComplications
1994
Characterization of a Vitamin D3-Resistant Human Chronic Myelogenous Leukemia Cell Line
Lasky S, Posner M, Iwata K, Santos-Moore A, Yen A, Samuel V, Clark J, Maizel A. Characterization of a Vitamin D3-Resistant Human Chronic Myelogenous Leukemia Cell Line. Blood 1994, 84: 4283-4294. PMID: 7994044, DOI: 10.1182/blood.v84.12.4283.bloodjournal84124283.Peer-Reviewed Original ResearchMeSH KeywordsBase SequenceCalcitriolCell DifferentiationCell DivisionDNA, NeoplasmDrug ResistanceGene Expression Regulation, LeukemicHumansLeukemia, Myelogenous, Chronic, BCR-ABL PositiveMolecular Sequence DataNeoplasm ProteinsPhosphorylationProtein BindingProtein Processing, Post-TranslationalReceptors, CalcitriolRetinoblastoma ProteinTetradecanoylphorbol AcetateTumor Cells, CulturedConceptsVitamin D3 treatmentVitamin D3Vitamin D3 receptorD3 treatmentD3 receptorsLeukemia cell linesMyelogenous leukemia cell lineChronic myelogenous leukemia cell lineD3 receptor activationCell linesDifferentiation-specific antigensReceptor activationInduction of differentiationAntiproliferative effectsHuman chronic myelogenous leukemia cell lineResistant cellsD3ReceptorsImmunoblot analysisTreatmentRetinoblastoma gene productProliferationCellsSimilar patternMobility shift studies