2021
Chapter 10 Phosphatonins
Tebben P, Kumar R. Chapter 10 Phosphatonins. 2021, 215-233. DOI: 10.1016/b978-0-12-813073-5.00010-1.ChaptersSecreted frizzled-related protein 4X-linked hypophosphatemic ricketsPhosphorus balanceCell membrane integrityTumor-induced osteomalaciaFrizzled-related protein 4Fibroblast growth factor 23Matrix extracellular phosphoglycoproteinPhosphate homeostasisRenal phosphate reabsorptionPhosphate absorptionAbnormal phosphate homeostasisIntestinal phosphate absorptionMembrane integrityPhosphorusFibroblast growth factor 7Parathyroid hormonePhosphaturic peptidesHypophosphatemic ricketsPhosphate reabsorptionVitamin DRenal reabsorptionHypophosphatemic disordersNovel treatmentTumoral calcinosis
2013
Chapter 16 Phosphatonins
Tebben P, Berndt T, Kumar R. Chapter 16 Phosphatonins. 2013, 373-390. DOI: 10.1016/b978-0-12-415853-5.00016-9.ChaptersMatrix extracellular phosphoglycoproteinSecreted frizzled-related protein 4Skeletal mineralizationAssociated with abnormal mineralizationActive vitamin D metaboliteFrizzled-related protein 4Fibroblast growth factor 23Vitamin D metabolitesRenal phosphate reabsorptionIntestinal phosphate absorptionPhosphaturic peptidesParathyroid hormoneD metabolitesChronic hypophosphatemiaPhosphate reabsorptionAbnormal mineralizationProtein 4Phosphorus homeostasisPhosphate homeostasisBone mineralizationEnergy homeostasisCell membrane integrityFGF23Phosphate absorption
2005
Secreted frizzled-related protein-4 reduces sodium–phosphate co-transporter abundance and activity in proximal tubule cells
Berndt T, Bielesz B, Craig T, Tebben P, Bacic D, Wagner C, O’Brien S, Schiavi S, Biber J, Murer H, Kumar R. Secreted frizzled-related protein-4 reduces sodium–phosphate co-transporter abundance and activity in proximal tubule cells. Pflügers Archiv - European Journal Of Physiology 2005, 451: 579-587. PMID: 16151791, DOI: 10.1007/s00424-005-1495-2.ChaptersConceptsSecreted frizzled-related protein 4Na+-dependent Pi uptakeRenal Pi excretionOpossum kidneyProximal tubulesPi excretionFractional excretion of PiResponse to hypophosphatemiaFrizzled-related protein 4Excretion of PiEffect of secreted frizzled-related protein 4Proximal tubule cellsBrush border of the proximal tubuleCo-transportNa+-dependent Pi transportRenal brush border membraneRenal BBMVOK cellsTubule cellsRenal phosphateSurface expressionTransporter abundanceBrush border membraneProtein 4Infusion