Stephanie Nichols-Burns, PhD, MS, HCLD
Associate Research ScientistCards
Contact Info
About
Titles
Associate Research Scientist
Biography
Stephanie M. Nichols-Burns, PhD, joined Yale Fertility Center in 2017. She is an Associate Research Scientist and the IVF Laboratory Director of Research. She obtained her BS in Biology from The College of William and Mary, an MS in Marine Science from Moss Landing Marine Laboratories studying shark reproduction and early development, and her PhD at the University of New Orleans under one of the pioneers of human IVF. Her doctoral studies investigated aging effects on oocyte quality and reproductive senescence in a non-human primate model (macaques). After spending several years at the Caribbean Primate Research Center Reproductive Biology Program in Puerto Rico, she relocated overseas and investigated ovarian tissue cryopreservation in Erlangen, Germany with the first group in Germany to produce a live birth following reimplantation of cryopreserved ovarian tissue into a cancer survivor. Following these research experiences, she made a natural transition into clinical IVF where she has been able to apply her gained knowledge to helping patients achieve their dreams of parenthood.
Dr. Nichols-Burns is an active member of the American Society of Reproductive Medicine (ASRM), Society for Assisted Reproductive Technology (SART), Society of Reproductive Biologists and Technologists (SRBT), and New York Metropolitan Embryologist Society (NYMES). She is a member of the SART Executive Council as Chair of the Validation Committee. She is also a member of the SART Education Committee and Chair of the SRBT Education Committee. In addition, she participates in collaborative research, serves as a reviewer for multiple journals, and has published several original, peer-reviewed research articles.
Appointments
Obstetrics, Gynecology & Reproductive Sciences
Associate Research ScientistPrimary
Other Departments & Organizations
Education & Training
- PhD
- University of New Orleans (2007)
- MS
- San Jose State University (2001)
Research
Research at a Glance
Yale Co-Authors
Publications Timeline
David Seifer, MD
Cihan Halicigil, HCLD, PhD, MSc
Karen Jubanyik, MD
Murat Basar, PhD
Mursal Gardezi, MD
Xiao-Bing Gao, PhD
Publications
2024
SERUM ANTI-MULLERIAN HORMONE IS ASSOCIATED WITH PREOVULATORY FOLLICLE CUMULUS CELL MITOCHONDRIAL DNA COPY NUMBER
Volovsky M, Seifer D, Sahin G, Chaplia O, Nichols-Burns S, Basar M, Seli E, Halicigil C. SERUM ANTI-MULLERIAN HORMONE IS ASSOCIATED WITH PREOVULATORY FOLLICLE CUMULUS CELL MITOCHONDRIAL DNA COPY NUMBER. Fertility And Sterility 2024, 122: e199. DOI: 10.1016/j.fertnstert.2024.07.662.Peer-Reviewed Original Research
2022
FROM OOCYTES TO A LIVE BIRTH: DOES PGT-A HELP OR HARM?
Sabbagh R, S N, Halicigil C, Quinlan J, Shah J, Korkidakis A, Penzias A, Patrizio P, Sakkas D. FROM OOCYTES TO A LIVE BIRTH: DOES PGT-A HELP OR HARM? Fertility And Sterility 2022, 118: e10-e11. DOI: 10.1016/j.fertnstert.2022.09.232.Peer-Reviewed Original ResearchICSI IS ASSOCIATED WITH LOWER BLASTULATION RATES COMPARED TO CONVENTIONAL IVF AMONG COUPLES WITH NON-MALE FACTOR INFERTILITY AND LOW OOCYTE YIELD
Beroukhim G, Seifer D, Chaplia O, Nichols-Burns S, Basar M, Halicigil C. ICSI IS ASSOCIATED WITH LOWER BLASTULATION RATES COMPARED TO CONVENTIONAL IVF AMONG COUPLES WITH NON-MALE FACTOR INFERTILITY AND LOW OOCYTE YIELD. Fertility And Sterility 2022, 118: e143. DOI: 10.1016/j.fertnstert.2022.08.419.Peer-Reviewed Original Research
2021
Miscarriage determination in first trimester based on alpha-fetoprotein extracted from sanitary pads
Mor A, Gardezi M, Jubanyik K, Simsek B, Seifer DB, Patrizio P, Esencan E, Imamoglu G, Zhang M, Nichols-Burns SM, Taylor HS. Miscarriage determination in first trimester based on alpha-fetoprotein extracted from sanitary pads. Fertility And Sterility 2021, 116: 462-469. PMID: 33461753, DOI: 10.1016/j.fertnstert.2020.10.006.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsExtrauterine pregnancyVaginal bloodAlpha-fetoproteinOngoing pregnancyAFP levelsSanitary padsHigh alpha-fetoprotein levelsOngoing pregnancy groupProspective cohort studyAlpha-fetoprotein levelsAcademic medical centerPregnancy groupCohort studyMiscarriage casesFirst trimesterOffice visitsMedical CenterMAIN OUTCOMEPregnancyMedian levelsMiscarriageBloodAnxiety levelsAFPCharacteristic analysis
2019
A step towards the automation of intracytoplasmic sperm injection: real time confirmation of mouse and human oocyte penetration and viability by electrical resistance measurement
Mor A, Zhang M, Esencan E, Simsek B, Nichols-Burns SM, Liu Y, Lo J, Kelk DA, Flores V, Gao XB, Seli E. A step towards the automation of intracytoplasmic sperm injection: real time confirmation of mouse and human oocyte penetration and viability by electrical resistance measurement. Fertility And Sterility 2019, 113: 234-236. PMID: 31883732, DOI: 10.1016/j.fertnstert.2019.09.023.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsIntracytoplasmic sperm injectionICSI pipetteSperm injectionOocyte penetrationIntact oolemmaOocyte retrieval procedureMann-Whitney testMouse oocytesOocyte retrievalFemale miceMAIN OUTCOMEAcademic centersImmature oocytesHuman oocytesMature oocytesObjective toolMiceOocytesWomenVisual assessmentPipetteInjectionOolemmaStep 1GroupDay 2 laser assisted hatching (AH) significantly improves implantation rates in fresh blastocyst transfers
Bjorkman S, Nichols-Burns S, Lo J, Kodaman N, Kodaman P, Kelk D. Day 2 laser assisted hatching (AH) significantly improves implantation rates in fresh blastocyst transfers. Fertility And Sterility 2019, 112: e292. DOI: 10.1016/j.fertnstert.2019.07.856.Peer-Reviewed Original ResearchA step towards the automation of intracytoplasmic sperm injection (ICSI): real time confirmation of oocyte penetration by electrical resistance measurement
Mor A, Zhang M, Esencan E, Simsek B, Nichols-Burns S, Liu Y, Lo J, Kelk D, Gao X, Seli E. A step towards the automation of intracytoplasmic sperm injection (ICSI): real time confirmation of oocyte penetration by electrical resistance measurement. Fertility And Sterility 2019, 112: e90-e91. DOI: 10.1016/j.fertnstert.2019.07.357.Peer-Reviewed Original ResearchPrediction of pregnancy outcome in women with first trimester bleeding by the detection of alpha-fetoprotein (AFP) in vaginal blood
Mor A, Jubanyik K, Gardezi M, Nichols-Burns S, Zhang M, Esencan E, Simsek B, Seifer D, Taylor H. Prediction of pregnancy outcome in women with first trimester bleeding by the detection of alpha-fetoprotein (AFP) in vaginal blood. Fertility And Sterility 2019, 112: e312. DOI: 10.1016/j.fertnstert.2019.07.906.Peer-Reviewed Original ResearchRepeated semen exposure decreases cervicovaginal SIVmac251 infection in rhesus macaques
Abdulhaqq S, Martinez M, Kang G, Rodriguez I, Nichols S, Beaumont D, Joseph J, Azzoni L, Yin X, Wise M, Weiner D, Liu Q, Foulkes A, Münch J, Kirchhoff F, Coutifaris C, Tomaras G, Sariol C, Marx P, Li Q, Kraiselburd E, Montaner L. Repeated semen exposure decreases cervicovaginal SIVmac251 infection in rhesus macaques. Nature Communications 2019, 10: 3753. PMID: 31434895, PMCID: PMC6704120, DOI: 10.1038/s41467-019-11814-5.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCD4+ T cellsFemale reproductive tractSemen exposureT cellsIncreased infiltration of CD4+ T cellsMale-to-female HIV transmissionCirculating CD4+ T cellsInfiltration of CD4+ T cellsExposure to semenEffect of semenNon-human primatesExpression of Mx1Anti-HIV mechanismsCervicovaginal mucosaSIVmac251 challengeSIVmac251 infectionCCR5 expressionIn vivo evidenceHIV acquisitionHIV infectionHIV transmissionAssociated with activationIncreased infiltrationRhesus macaquesReproductive tract
2018
Analysis of a simulated liquid nitrogen storage tank failure
Kelk D, Liu Y, Nichols-Burns S, Lo J, Reed M, Pomeroy K. Analysis of a simulated liquid nitrogen storage tank failure. Fertility And Sterility 2018, 110: e18-e19. DOI: 10.1016/j.fertnstert.2018.07.069.Peer-Reviewed Original ResearchCitations