James Macy Jr, DVM
Professor of Comparative MedicineDownloadHi-Res Photo
Cards
Appointments
Comparative Medicine
Primary
Additional Titles
Vice Chairman for Clinical Affairs, Comparative Medicine
Attending Veterinarian
Director, Yale Animal Resources Center
Contact Info
Comparative Medicine
PO Box 208016
New Haven, CT 06520-8016
United States
Appointments
Comparative Medicine
Primary
Additional Titles
Vice Chairman for Clinical Affairs, Comparative Medicine
Attending Veterinarian
Director, Yale Animal Resources Center
Contact Info
Comparative Medicine
PO Box 208016
New Haven, CT 06520-8016
United States
Appointments
Comparative Medicine
Primary
Additional Titles
Vice Chairman for Clinical Affairs, Comparative Medicine
Attending Veterinarian
Director, Yale Animal Resources Center
Contact Info
Comparative Medicine
PO Box 208016
New Haven, CT 06520-8016
United States
About
Titles
Professor of Comparative Medicine
Vice Chairman for Clinical Affairs, Comparative Medicine; Attending Veterinarian; Director, Yale Animal Resources Center
Appointments
Comparative Medicine
ProfessorPrimary
Other Departments & Organizations
- Comparative Medicine
- Mouse Metabolic Phenotyping Center
- Yale Ventures
Education & Training
- DVM
- University of Georgia (1992)
- Postdoctoral Fellow
- Yale University
Research
Research at a Glance
Yale Co-Authors
Frequent collaborators of James Macy's published research.
Publications Timeline
A big-picture view of James Macy's research output by year.
Caroline Zeiss, DACVP, DACLAM
Gerald I Shulman, MD, PhD, MACP, MACE, FRCP
Susan Compton, PhD
9Publications
89Citations
Publications
2024
The mouse metabolic phenotyping center (MMPC) live consortium: an NIH resource for in vivo characterization of mouse models of diabetes and obesity
Laughlin M, McIndoe R, Adams S, Araiza R, Ayala J, Kennedy L, Lanoue L, Lantier L, Macy J, Malabanan E, McGuinness O, Perry R, Port D, Qi N, Elias C, Shulman G, Wasserman D, Lloyd K. The mouse metabolic phenotyping center (MMPC) live consortium: an NIH resource for in vivo characterization of mouse models of diabetes and obesity. Mammalian Genome 2024, 1-12. PMID: 39191872, DOI: 10.1007/s00335-024-10067-y.Peer-Reviewed Original ResearchConceptsMouse Metabolic Phenotyping CentersMouse model of diabetesModels of diabetesNational Institutes of HealthNational Institute for DiabetesDigestive and Kidney DiseasesBehavioral phenotyping testsRenal functionProcedure in vivoFood intakeIn vivo characterizationMouse modelHeterogeneity of diabetesKidney diseaseBody compositionPhenotyping CentersInstitutes of HealthMiceObesityDiabetesPhenotypic testsWhole-body carbohydrateInsulin actionLipid metabolismLiving mice
2019
Chapter 13 Viral Disease
Macy J, Compton S. Chapter 13 Viral Disease. 2019, 541-568. PMCID: PMC7153344, DOI: 10.1016/b978-0-12-814338-4.00013-1.Peer-Reviewed Original ResearchCitationsAltmetric
2004
Pathogenesis of enterotropic mouse hepatitis virus in immunocompetent and immunodeficient mice.
Compton SR, Ball-Goodrich LJ, Johnson LK, Johnson EA, Paturzo FX, Macy JD. Pathogenesis of enterotropic mouse hepatitis virus in immunocompetent and immunodeficient mice. Comparative Medicine 2004, 54: 681-9. PMID: 15679267.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsT cell-deficient miceCell-deficient miceMouse hepatitis virusBALB/cGastrointestinal tractC57BL/6 miceLymphoid tissueViral RNASubclinical infectionHepatitis virusInfected B-cell-deficient miceSmall intestineEnterotropic mouse hepatitis virusB cell-deficient miceImmunocompetent BALB/cMost natural infectionsChronic subclinical infectionMultiple organ systemsTranscriptase-polymerase chain reaction analysisImmunocompetent miceLethal infectionEnterotropic strainsT cellsImmunodeficient miceIntestinal mucosaPromises to keep (Part 2).
Jacoby RO, Macy JD. Promises to keep (Part 2). Comparative Medicine 2004, 54: 11-2. PMID: 15027613.Peer-Reviewed Original ResearchCitationsTransmission of enterotropic mouse hepatitis virus from immunocompetent and immunodeficient mice.
Compton SR, Ball-Goodrich LJ, Paturzo FX, Macy JD. Transmission of enterotropic mouse hepatitis virus from immunocompetent and immunodeficient mice. Comparative Medicine 2004, 54: 29-35. PMID: 15027615.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsMeSH KeywordsAnimalsAnimals, Outbred StrainsFecesFemaleHepatitis, Viral, AnimalImmunocompetenceImmunocompromised HostInfectious Disease Transmission, VerticalMiceMice, Inbred StrainsMurine hepatitis virusReverse Transcriptase Polymerase Chain ReactionRNA, ViralRodent DiseasesSentinel SurveillanceSpecies SpecificityVirus SheddingConceptsCell-deficient miceEnterotropic mouse hepatitis virusT cell-deficient miceMouse hepatitis virusInfected miceIntestinal infectionsC57BL/6 miceHepatitis virusB cell-deficient miceViral RNABALB/c miceSevere disseminated diseaseNon-infectious RNADisseminated diseaseNaive miceC miceMHV infectionImmunodeficient miceSentinel miceBALB/ cViral transmissionInfectionMiceVirus RNAWeeks
2003
Pathogenesis of mouse hepatitis virus infection in gamma interferon-deficient mice is modulated by co-infection with Helicobacter hepaticus.
Compton SR, Ball-Goodrich LJ, Zeiss CJ, Johnson LK, Johnson EA, Macy JD. Pathogenesis of mouse hepatitis virus infection in gamma interferon-deficient mice is modulated by co-infection with Helicobacter hepaticus. Comparative Medicine 2003, 53: 197-206. PMID: 12784855.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsIFN-gamma KO miceGamma interferon-deficient miceMouse hepatitis virusInterferon-deficient miceDevelopment of peritonitisKO miceH. hepaticusMultisystemic infectionHelicobacter hepaticusMouse hepatitis virus infectionHepatitis virus infectionAberrant immune responseSelf-limiting infectionMinimal pathologic changesMultifocal hepatic necrosisLater time pointsAcute necrotizingAcute peritonitisAcute phaseInflammatory lesionsImmunocompetent miceChronic infectionHepatic necrosisMHV infectionPathologic changes
2002
Assessment of static isolator cages with automatic watering when used with conventional husbandry techniques as a factor in the transmission of mouse hepatitis virus.
Macy JD, Cameron GA, Ellis SL, Hill EA, Compton SR. Assessment of static isolator cages with automatic watering when used with conventional husbandry techniques as a factor in the transmission of mouse hepatitis virus. Journal Of The American Association For Laboratory Animal Science 2002, 41: 30-5. PMID: 12109894.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsFilter-top cagesMouse hepatitis virusUninoculated miceHepatitis virusCages of miceTransmission of infectionExamination of fecesLong-term useImmunocompetent miceHigh virus concentrationsPolymerase chain reaction amplificationMiceChain reaction amplificationWeeksStandard cagesMHV-A59Fecal samplesRoutine husbandrySerologyTest cageVirusInfected cagesInfectionReaction amplificationRows of cages
2001
Anisocoria and middle cerebral artery saccular (berry) aneurysm in a rhesus macaque (Macaca mulatta).
Ovadia S, Zeiss C, Reuter J, Macy J. Anisocoria and middle cerebral artery saccular (berry) aneurysm in a rhesus macaque (Macaca mulatta). Comparative Medicine 2001, 51: 562-6. PMID: 11924821.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsRight optic tractLeft pupilOptic tractRight middle cerebral arteryIntracranial aneurysmsRhesus macaquesParasympathetic efferent pathwaysRight middle cerebralLeft oculomotor nerveMiddle cerebral arteryInternal carotid arteryFemale rhesus macaquesMiddle cerebralNeurologic deficitsArteriosclerotic changesCerebral arteryEfferent pathwaysOculomotor nerveUnrelated reasonsVisual deficitsBerry aneurysmsCarotid arteryUnruptured aneurysmsConstrictor muscleAnisocoriaLatex sensitivity in a macaque (Macaca mulatta).
Macy J, Huether M, Beattie T, Findlay H, Zeiss C. Latex sensitivity in a macaque (Macaca mulatta). Comparative Medicine 2001, 51: 467-72. PMID: 11924808.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsDelayed-type hypersensitivity reactionFlares of dermatitisAllergen-specific IgE testingSkin prick testPunch biopsy specimenAdult Macaca mulattaDifferen-tial diagnosisLatex sensitivityCorneal stainingThyroid profilePrick testAtopic dermatitisIgE testingLatex allergyHypersensitivity reactionsBiopsy specimenContact allergensSignificant inflammationEosinophilic dermatitisOriginal biopsyInguinal regionAllergic dermatitisSkin scrapingsVinyl glovesFourteen weeks
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Comparative Medicine
PO Box 208016
New Haven, CT 06520-8016
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