Relation of glomerular filtration to insulin resistance and related risk factors in obese children
Magen D, Halloun R, Galderisi A, Caprio S, Weiss R. Relation of glomerular filtration to insulin resistance and related risk factors in obese children. International Journal Of Obesity 2021, 46: 374-380. PMID: 34725443, DOI: 10.1038/s41366-021-01001-2.Peer-Reviewed Original ResearchConceptsGlomerular filtration rateInsulin sensitivityObese childrenInsulin resistanceBlood pressureFiltration rateRisk factorsWhole-body insulin sensitivityChildhood insulin resistanceFuture kidney diseaseRelation of eGFRSignificant renal morbiditySpectrum of obesityCardiovascular risk factorsPresence of microalbuminuriaSystolic blood pressureRelated risk factorsHepatic insulin sensitivityBody insulin sensitivityObjectiveChildhood obesityRenal morbidityClinical outcomesGlucose toleranceMale sexKidney disease