Adjunct Faculty
Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsAlfonso Galderisi, MD, PhD
he/him/his
Associate Professor AdjunctAbout
Research
Publications
2026
1298-OR: CGM-Derived Disposition Index in Stage 1 Type 1 Diabetes (T1D)
MARCHIORI H, SCHIAVON M, TICHY E, ALGUARD M, DESOUSA M, DEL FAVERO S, GAGLIA J, SHERR J, MAN C, GALDERISI A. 1298-OR: CGM-Derived Disposition Index in Stage 1 Type 1 Diabetes (T1D). Diabetes 2026, 75 DOI: 10.2337/db26-1298-or.Peer-Reviewed Original ResearchOral glucose tolerance testDisposition indexOral glucose tolerance test dataStage 1 diseaseGlucose tolerance testClinically relevant outcomesBeta cell functionOral minimal modelC-peptideNational Institutes of HealthTolerance testNational InstituteCohort of peopleInstitutes of HealthCell functionTime pointsPractical burdenRelevant outcomesT1DStudy proceduresCGM profiles1022-OR: Increase in Insulin Clearance Features Rapid Disease Progression in Children with Preclinical Type 1 Diabetes (T1D)
GALDERISI A, MARCHIORI H, BONET J, MAN C, DAYAN C, CARR A, MORAN T, HEROLD K, CUTHBERTSON D, PETRELLI A, ISMAIL H. 1022-OR: Increase in Insulin Clearance Features Rapid Disease Progression in Children with Preclinical Type 1 Diabetes (T1D). Diabetes 2026, 75 DOI: 10.2337/db26-1022-or.Peer-Reviewed Original ResearchSlow progressorsRapid progressorsDisease progressionB cellsHigher insulin clearancePreclinical type 1 diabetesRapid disease progressionB cell functionCystic Fibrosis FoundationSafety monitoring boardType 1 diabetesOral minimal modelC-peptide/insulinFollow-upMetabolic phenotypeMonitoring boardInsulin clearanceInsulin secretionDiabetes InstituteAge groupsInsulin concentrationsInsulinProgressorsT1DLeona M. and Harry B. Helmsley Charitable Trust2382-P: Modelling β-Cell Decline across Preclinical Type 1 Diabetes (T1D)
CARR A, PERAZZOLO S, HEDRICK J, SENIOR P, ISMAIL H, MORAN T, DAYAN C, GALDERISI A. 2382-P: Modelling β-Cell Decline across Preclinical Type 1 Diabetes (T1D). Diabetes 2026, 75 DOI: 10.2337/db26-2382-p.Peer-Reviewed Original ResearchAUC C-peptideC-peptideOral minimal modelB cellsPreclinical type 1 diabetesB cell responsesNegative predictive valueNational Institute of AllergyB cell functionNational InstituteInstitute of AllergyDigestive and Kidney DiseasesType 1 diabetesClinical Trials NetworkNational Institutes of Health (NIH)Kidney diseaseStudy groupNon-progressiveFunctional deteriorationProgression probabilityIntervention designPredictive valueTrials NetworkT1DAUCEPS10.02 Continuous glucose monitoring to track metabolic changes in children and adolescents with cystic fibrosis before and after ETI initiation
Galderisi A, Weiss L, Marchiori H, Besancon A, Sakhi D, Bonnel A, Sermet-Gaudelus I. EPS10.02 Continuous glucose monitoring to track metabolic changes in children and adolescents with cystic fibrosis before and after ETI initiation. Journal Of Cystic Fibrosis 2026, 25: s63. DOI: 10.1016/s1569-1993(26)00327-9.Peer-Reviewed Original ResearchRelevance of Quantitative Measures of Beta-Cell Function in Clinical Practice
Galderisi A, Dayan C, Colhoun H, Gregory J. Relevance of Quantitative Measures of Beta-Cell Function in Clinical Practice. Hormone Research In Paediatrics 2026, 1-15. PMID: 42113731, PMCID: PMC13218698, DOI: 10.1159/000552501.Peer-Reviewed Original ResearchBeta-cell functionC-peptide measurementsMeasures of beta-cell functionC-peptideClinical managementClinical management of T1DResidual beta-cell functionLoss of beta-cell functionBeta-cell healthClinical practicePatient-specific factorsLong-term complicationsLower insulin requirementsResidual C-peptidePancreatic beta-cell functionStage 3Chronic autoimmune diseaseBeta-cell damageBeta-cell dysfunctionType 1 diabetesBeta-cell populationMultiple islet autoantibodiesRoutine clinical careDisease-modifying therapiesStage 1High-Intensity Interval Training: Safe and Beneficial Physical Activity Strategy in Adolescents with Type 1 Diabetes
Soto J, Rozas K, León A, Ponce N, Venegas R, Pelicand J, Paiva O, Galderisi A, Fox L, Gleisner A. High-Intensity Interval Training: Safe and Beneficial Physical Activity Strategy in Adolescents with Type 1 Diabetes. Hormone Research In Paediatrics 2026, 1-15. PMID: 41843720, DOI: 10.1159/000551568.Peer-Reviewed Original ResearchHigh-intensity interval trainingPhysical activityAerobic capacityHome-based HIITDepressive symptomsEffects of high-intensity interval trainingPhysical activity strategiesIntensity interval trainingMaximal oxygen consumptionMental health benefitsMonths of trainingType 1 diabetesEvaluate metabolic effectsLean mass increaseCardiovascular risk factorsStrength endurancePhysical fitnessInterval trainingLack of motivationCardiovascular healthBlood glucoseSecondary outcomesBody compositionTanner stage IIIDaily insulin doseNeurobehavioral outcomes at 12 months in very preterm infants monitored with continuous glucose monitoring at birth compared with full-term infants
Lasagni C, Cusinato M, Guiducci S, Avagliano L, Tolettini B, Res G, Savio F, Trevisanuto D, Priante E, Baraldi E, Galderisi A, Brigadoi S, Di Giorgio E. Neurobehavioral outcomes at 12 months in very preterm infants monitored with continuous glucose monitoring at birth compared with full-term infants. Scientific Reports 2026, 16: 9489. PMID: 41702956, PMCID: PMC13005029, DOI: 10.1038/s41598-026-37286-4.Peer-Reviewed Original ResearchConceptsVPT infantsFT infantsFull-termContinuous glucose monitoringFull-term infantsLong-term outcomesPreterm infantsMonths CAVery pretermNeurodevelopmental outcomesNeurodevelopmental delayGlucose monitoringPostnatal weekFollow-upGlycaemic controlNeurobehavioral outcomesInfantsGlucose variabilityGlycaemic variabilityLab-based tasksGlucose levelsPretermEarly detectionCognitive disturbancesBirthTask-free functional connectivity changes before and after hyper- and hypoglycemia in very preterm neonates
Perkins G, Bianco G, Guiducci S, De Pietri E, Res G, Savio F, Trevisanuto D, Priante E, Baraldi E, Galderisi A, Brigadoi S. Task-free functional connectivity changes before and after hyper- and hypoglycemia in very preterm neonates. Neurophotonics 2026, 13: s13008. PMID: 41924494, PMCID: PMC13037429, DOI: 10.1117/1.nph.13.s1.s13008.Peer-Reviewed Original ResearchPreterm infantsGlucose profilesBlood glucose concentrationEarly biomarkersVery preterm neonatesVery preterm infantsVery preterm newbornsEpisodes of hyper-Impaired glucose controlPreterm brainPreterm neonatesPreterm newbornsGlucose concentrationGlycemic changesRight prefrontal regionsGlucose controlLeft parietal regionsFunctional connectivityTask-free functional connectivityGlucose fluctuationsPretermBrain vulnerabilityFunctional connectivity changesBrain areasPrefrontal cortex
2025
Impact of severe hypoglycemia on cerebral hemodynamics in very preterm neonates
Perkins G, Guiducci S, Res G, Savio F, Trevisanuto D, Priante E, Galderisi A, Baraldi E, Brigadoi S. Impact of severe hypoglycemia on cerebral hemodynamics in very preterm neonates. Progress In Biomedical Optics And Imaging 2025, 13935: 139350c-139350c-3. DOI: 10.1117/12.3098359.Peer-Reviewed Original ResearchPROMETEUS: hybrid TD-NIRS and SCOS instrument for real-time monitoring of brain metabolism in preterm neonates: system architecture and characterization
Negretti F, Amendola C, Brigadoi S, Buttafava M, Cooper R, Man C, Durduran T, Faure F, Fornasier M, Galderisi A, Lacerenza M, Marchiori H, Scarpa A, Spinelli L, Torricelli A, Contini D. PROMETEUS: hybrid TD-NIRS and SCOS instrument for real-time monitoring of brain metabolism in preterm neonates: system architecture and characterization. Progress In Biomedical Optics And Imaging 2025, 13935: 139350j-139350j-3. DOI: 10.1117/12.3098366.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
News
News
- November 25, 2025
Alfonso Galderisi, MD, PhD: What to Know During Diabetes Awareness Month
- October 08, 2025Source: Science Press Releases
vTv Therapeutics Announces New Appointments to its Scientific Advisory Board
- February 28, 2024
Find Yale Pediatrics at the 2024 Pediatric Academic Societies (PAS) Meeting