2023
Effect of retrobulbar prostaglandin analog injection on orbital fat in rats
Cosan S, İnam O, Kaya B, Atilla P, Ocal O, Arat A, Karakaya J, Arat Y. Effect of retrobulbar prostaglandin analog injection on orbital fat in rats. International Ophthalmology 2023, 43: 4985-4990. PMID: 37847476, DOI: 10.1007/s10792-023-02901-0.Peer-Reviewed Original ResearchConceptsProstaglandin analogsAdipocyte densityRetrobulbar injectionIn vivo studiesOrbital fatFat atrophySide effectsAdult male Wistar albino ratsTopical prostaglandin analogsMale Wistar albino ratsFollow-up durationControl sideInjection of PAWistar albino ratsThyroid orbitopathyLeft orbitOrbital diseaseRight orbitRat modelAnimal modelsAnalog injectionRatsImage analysis softwareImageJ image analysis softwareTreatment of diseases
2019
Retinal and Choroidal Optical Coherence Tomography Findings of Carotid Cavernous Fistula
Inam O, Arat Y, Yavas G, Arat A. Retinal and Choroidal Optical Coherence Tomography Findings of Carotid Cavernous Fistula. American Journal Of Ophthalmology 2019, 206: 264-273. PMID: 31226247, DOI: 10.1016/j.ajo.2019.06.010.Peer-Reviewed Original ResearchConceptsChoroidal vascularity indexTortuosity indexPatient groupControl groupCentral foveal thicknessClinically affected eyesSubfoveal choroidal thicknessOptical coherence tomography imagesVenous drainage patternCarotid-cavernous fistulaHealthy control subjectsCG groupFoveal thicknessChoroidal thicknessCavernous fistulaConsecutive patientsControl subjectsVascular indexPatientsTomography imagesFistulaSFCTEyesGroupClinic
2017
Comparison of Colorado Microdissection Needle Versus Scalpel Incision for Aesthetic Upper and Lower Eyelid Blepharoplasty
Arat Y, Sezenoz A, Bernardini F, Alford M, Tepeoglu M, Allen R. Comparison of Colorado Microdissection Needle Versus Scalpel Incision for Aesthetic Upper and Lower Eyelid Blepharoplasty. Ophthalmic Plastic And Reconstructive Surgery 2017, 33: 430-433. PMID: 27811630, DOI: 10.1097/iop.0000000000000820.Peer-Reviewed Original ResearchConceptsColorado needleScar cosmesisAesthetic blepharoplastySkin incisionScalpel incisionEyelid skin incisionsComparative case seriesPostoperative day 1No adverse eventsTranscutaneous lower blepharoplastyHistological tissue damageInstitutional review boardBlepharoplasty surgeryNo significant differenceCase seriesAdverse eventsClinical differencesLower blepharoplastyHollander scoreDay 1EcchymosisCosmesisIncisionBlepharoplastyScar formation
2016
Comparison of botulinum toxin-A injection in lacrimal gland and conjunctivodacryocystorhinostomy for treatment of epiphora due to proximal lacrimal system obstruction
Kaynak P, Karabulut G, Ozturker C, Fazil K, Arat Y, Perente I, Akar S, Yilmaz O, Demirok A. Comparison of botulinum toxin-A injection in lacrimal gland and conjunctivodacryocystorhinostomy for treatment of epiphora due to proximal lacrimal system obstruction. Eye 2016, 30: 1056-1062. PMID: 27197871, PMCID: PMC4985683, DOI: 10.1038/eye.2016.88.Peer-Reviewed Original ResearchConceptsLacrimal system obstructionBotulinum toxin A injectionSystem obstructionLacrimal glandUpper lacrimal system obstructionDegree of epiphoraLacrimal system irrigationSchirmer test resultsSchirmer 1 testTreatment of epiphoraProximal canalicular obstructionEfficacy of botulinum toxin A injectionsEvaluation of epiphoraPunctate epitheliopathyCanalicular obstructionTube dislocationSurgical experienceTube insertionConjunctivodacryocystorhinostomyEpiphoraGroup 2Group 1Granuloma formationLess-invasivePostoperative care
2015
Association of Disease Activity with Serum and Tear IL-2 Levels in Behçet Disease
Türkçüoğlu P, Arat Y, Kan E, Kan E, Chaudhry I, Koca S, Çeliker Ü, İlhan N. Association of Disease Activity with Serum and Tear IL-2 Levels in Behçet Disease. Ocular Immunology And Inflammation 2015, 24: 313-318. PMID: 26110544, DOI: 10.3109/09273948.2014.1003661.Peer-Reviewed Original ResearchConceptsIL-2 levelsInterleukin-2 levelsDisease activitySex-matched healthy participantsProspective case control studyAssociation of disease activitySignificant differenceBehcet's disease patientsCase-control studyStatistically significant differenceEnzyme-linked immunosorbent assay methodBehcet's patientsBehcet's diseaseActive diseaseInactive diseaseNo significant differenceControlled studiesPatientsStudy populationSerumDisease patientsControl groupDiseaseHealthy participantsAssociation
2013
Acute, Unilateral Transient Blepharoptosis of Unknown Etiology
Arat Y, Yazici B, Hekimhan-Kaynak P, Chaudhry I, Wladis E. Acute, Unilateral Transient Blepharoptosis of Unknown Etiology. Ophthalmic Plastic And Reconstructive Surgery 2013, 29: 396-399. PMID: 24022352, DOI: 10.1097/iop.0b013e31829d02c7.Peer-Reviewed Original ResearchConceptsUnilateral blepharoptosisLevator functionRare conditionUnknown etiologyHistory of flu-like illnessDecreased levator functionFlu-like syndromeFollow-up periodFlu-like illnessAcute ptosisTotal ptosisPupil abnormalitiesBlepharoptosisPtosisPatientsMedical recordsAffected sideEtiologyLimited motilityLevatorWorkupSyndromeAbnormalitiesClinicHistory
2011
Orbitofacial neurofibromatosis: clinical characteristics and treatment outcome
Chaudhry I, Morales J, Shamsi F, Al-Rashed W, Elzaridi E, Arat Y, Jacquemin C, Oystreck D, Bosley T. Orbitofacial neurofibromatosis: clinical characteristics and treatment outcome. Eye 2011, 26: 583-592. PMID: 22193879, PMCID: PMC3325560, DOI: 10.1038/eye.2011.336.Peer-Reviewed Original ResearchConceptsSurgical interventionNon-comparative case seriesDecreased visual acuityNeurofibromatosis type 1Ophthalmologic examinationOphthalmological monitoringPtosis repairTumor debulkingEyelid swellingVisual acuityResultsSixty patientsSurgical managementCase seriesPresenting signCosmetic consequencesCosmetic rehabilitationProcedural outcomesPatientsMedical recordsType 1Medical CentreMultiple proceduresClinical observationsDemographic dataPtosis
2009
CORNEOSCLERAL NECROSIS AFTER EPISCLERAL AU-198 BRACHYTHERAPY OF UVEAL MELANOMA
CHAUDHRY I, LIU M, SHAMSI F, ARAT Y, SHETLAR D, BONIUK M. CORNEOSCLERAL NECROSIS AFTER EPISCLERAL AU-198 BRACHYTHERAPY OF UVEAL MELANOMA. Retina 2009, 29: 73-79. PMID: 18728617, DOI: 10.1097/iae.0b013e3181863f7c.Peer-Reviewed Original ResearchConceptsCiliary body involvementRisk factorsTumor thicknessDry eyeUveal melanomaBody involvementEvidence of recurrent tumorSymptoms of dry eyeComplaints of dry eyesClinical records of patientsIntraocular pressure >Au-198Close follow-upForeign body sensationRecords of patientsAssociated risk factorsCiliochoroidal melanomaPrimary choroidalRadioactive plaquesRecurrent tumorsConjunctival flapIntraocular pressureScleral patchLevel of statistical significanceFailed treatment
2008
Inpatient preseptal cellulitis: experience from a tertiary eye care centre
Chaudhry I, Shamsi F, Elzaridi E, Al-Rashed W, Al-Amri A, Arat Y. Inpatient preseptal cellulitis: experience from a tertiary eye care centre. British Journal Of Ophthalmology 2008, 92: 1337. PMID: 18697809, DOI: 10.1136/bjo.2007.128975.Peer-Reviewed Original ResearchMeSH KeywordsAbscessAdolescentAdultAgedAnti-Bacterial AgentsCellulitisChildChild, PreschoolDrainageEyelid DiseasesFemaleHaemophilus InfectionsHumansInfantMaleMiddle AgedPostoperative ComplicationsSeverity of Illness IndexStaphylococcal InfectionsStreptococcal InfectionsTomography, X-Ray ComputedTreatment OutcomeConceptsPreseptal cellulitisAcute dacryocystitisSurgical interventionSystemic antibioticsTertiary eye-care centreReview of inpatientsOutcome of treatmentEyelid necrosisLid abscessEyelid edemaBlood culturesCicatricial ectropionRadiological evidenceAcute onsetOrbital septumHaemophilus influenzaeKlebsiella pneumoniaePatientsStreptococcus speciesDiagnostic criteriaPredisposing causeAdmitted patientsMicrobiological investigationsComplicationsEyelid
2007
Ptosis in Young Soft Contact Lens Wearers
Reddy A, Foroozan R, Arat Y, Edmond J, Yen M. Ptosis in Young Soft Contact Lens Wearers. Ophthalmology 2007, 114: 2370-2370.e1. PMID: 18054661, DOI: 10.1016/j.ophtha.2007.06.009.Peer-Reviewed Original ResearchRed Lesions of the Iris, Choroid, and Skin Secondary to Metastatic Carcinoma of the Thyroid: A Review
Arat Y, Boniuk M. Red Lesions of the Iris, Choroid, and Skin Secondary to Metastatic Carcinoma of the Thyroid: A Review. Survey Of Ophthalmology 2007, 52: 523-528. PMID: 17719373, DOI: 10.1016/j.survophthal.2007.06.006.Peer-Reviewed Original ResearchConceptsThyroid carcinomaChoroidal lesionsLeft eyeRight eyeDiagnosis of metastatic follicular thyroid carcinomaNodular lesionsCase of iris metastasisHistory of thyroid malignancyMetastatic follicular thyroid carcinomaMetastasis of thyroid carcinomaRight side of the noseReview of English literatureSlit-lamp examinationRadioactive iodine ablationFollicular thyroid carcinomaFollow-up periodChoroidal massChoroidal metastasisIris metastasisSubretinal hemorrhageIodine ablationIris massUveal metastasisSkin metastasesThyroid malignancyEmbolization of High-Flow Craniofacial Vascular Malformations with Onyx
Arat A, Cil B, Vargel I, Turkbey B, Canyigit M, Peynircioglu B, Arat Y. Embolization of High-Flow Craniofacial Vascular Malformations with Onyx. American Journal Of Neuroradiology 2007, 28: 1409-1414. PMID: 17698554, PMCID: PMC7977660, DOI: 10.3174/ajnr.a0547.Peer-Reviewed Original ResearchConceptsN-butyl-2-cyanoacrylateArteriovenous malformationsVascular malformationsEmbolic agentEffective liquid embolic agentHead and neck regionHigh-flow vascular malformationsCraniofacial vascular malformationsArteriovenous vascular malformationsBalloon-assisted embolizationLiquid embolic agentInduction of thrombosisFistula siteArterial feedersRetrospective reviewFistulous lesionsSurgical revisionArteriovenous fistulaEmbolization proceduresNeurological complicationsEndovascular treatmentAdjunctive maneuversBalloon assistanceCatheter entrapmentSurgical proceduresOutcome of Treated Orbital Cellulitis in a Tertiary Eye Care Center in the Middle East
Chaudhry I, Shamsi F, Elzaridi E, Al-Rashed W, Al-Amri A, Al-Anezi F, Arat Y, Holck D. Outcome of Treated Orbital Cellulitis in a Tertiary Eye Care Center in the Middle East. Ophthalmology 2007, 114: 345-354. PMID: 17270683, DOI: 10.1016/j.ophtha.2006.07.059.Peer-Reviewed Original ResearchMeSH KeywordsAbscessAdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsBacteriaCellulitisChildChild, PreschoolCombined Modality TherapyDrainageEye EnucleationEye Infections, BacterialFemaleHospitals, SpecialHumansInfantMaleMiddle AgedOphthalmologic Surgical ProceduresOphthalmologyOrbital DiseasesRetrospective StudiesRisk FactorsSaudi ArabiaTomography, X-Ray ComputedTreatment OutcomeConceptsOrbital cellulitisOrbital abscessTertiary eye care referral centerKing Khaled Eye Specialist HospitalDiagnosis of orbital cellulitisHistory of orbital traumaResolution of orbital cellulitisTertiary care eye centerTertiary eye care centerCases of orbital cellulitisEye care centerSevere visual lossCare centerReview of patientsClinical review of patientsSystemic antibiotic treatmentTertiary care centerResults of cultureUntreated sinusitisOral antibioticsVisual acuityVisual lossBlood culturesSystemic antibioticsReferral centerEpidemiology of giant-cell arteritis in an Arab population: a 22-year study
Chaudhry I, Shamsi F, Elzaridi E, Arat Y, Bosley T, Riley F. Epidemiology of giant-cell arteritis in an Arab population: a 22-year study. British Journal Of Ophthalmology 2007, 91: 715. PMID: 17229803, PMCID: PMC1955573, DOI: 10.1136/bjo.2006.108845.Peer-Reviewed Original ResearchConceptsTemporal artery biopsyGiant-cell arteritisBiopsy-proven giant-cell arteritisKing Khaled Eye Specialist HospitalNegative temporal artery biopsyCases of giant-cell arteritisBiopsy-negative groupBiopsy-positive groupBiopsy-proven casesArab populationSmall absolute numberArtery biopsyUntreated patientsClinical featuresClinical recordsLow incidenceCaucasian populationSpecialist HospitalAbsolute numberArteritisPatientsEpidemiologyStudy objectiveBiopsyPopulation
2006
Compressive Optic Neuropathy after Use of Oxidized Regenerated Cellulose in Orbital Surgery Review of Complications, Prophylaxis, and Treatment
Arat Y, Dorotheo E, Tang R, Boniuk M, Schiffman J. Compressive Optic Neuropathy after Use of Oxidized Regenerated Cellulose in Orbital Surgery Review of Complications, Prophylaxis, and Treatment. Ophthalmology 2006, 113: 333-337. PMID: 16406540, DOI: 10.1016/j.ophtha.2005.11.003.Peer-Reviewed Original ResearchConceptsCompressive optic neuropathyOxidized regenerated celluloseOptic neuropathyOrbital surgeryCases of compressive optic neuropathyOrbital explorationOrbital floor fracturesReview of complicationsSoft tissue densitySoft tissue massOrbital symptomsOrbital tumorsFloor fracturesOptic nerveCompartment syndromePostoperative patientsEnglish scientific literatureSurgeryComplicationsNeuropathyPatientsProgressive lossRecommended precautionsOperative siteTreatment purposes
2005
Leiomyoma of the Orbit and Periocular Region
Arat Y, Font R, Chaudhry I, Boniuk M. Leiomyoma of the Orbit and Periocular Region. Ophthalmic Plastic And Reconstructive Surgery 2005, 21: 16-22. PMID: 15677948, DOI: 10.1097/01.iop.0000150426.79781.54.Peer-Reviewed Original ResearchConceptsOrbital leiomyomaMass lesionFollow-upPeriorbital regionContrast-enhancing mass lesionWell-circumscribed mass lesionLost to follow-upFollow-up examinationRare tumorSubtotal excisionRetrospective reviewRadiological featuresLeiomyomaDifferential diagnosisImmunohistochemical techniquesHistopathological studiesEnglish literatureMonoclonal antibodiesTumorPatientsLesionsDiagnosisSubtotalRecurrenceExcision
2004
Congenital Microphthalmos With Orbital Cysts
Chaudhry I, Arat Y, Shamsi F, Boniuk M. Congenital Microphthalmos With Orbital Cysts. Ophthalmic Plastic And Reconstructive Surgery 2004, 20: 452-457. PMID: 15599246, DOI: 10.1097/01.iop.0000143716.12643.98.Peer-Reviewed Original ResearchConceptsOrbital cystCyst excisionCongenital microphthalmosTreated with cyst excisionTreated with enucleationFollow-up intervalMicrophthalmic globesMild microphthalmosCyst aspirationUnilateral casesCongenital malformationsClinical featuresClinical findingsCyst sizeMicrophthalmosComputed tomographyClinical recordsTreatment strategiesCosmetic issuesTreatment approachesExcisionCystsCosmesisPatientsGeneral conditionOrbital Venous Malformations: Current Multidisciplinary Treatment Approach
Arat Y, Mawad M, Boniuk M. Orbital Venous Malformations: Current Multidisciplinary Treatment Approach. JAMA Ophthalmology 2004, 122: 1151-1158. PMID: 15302655, DOI: 10.1001/archopht.122.8.1151.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedChildChild, PreschoolCombined Modality TherapyDilatation, PathologicEmbolization, TherapeuticFemaleHumansInfantLaser TherapyMaleMiddle AgedOphthalmologic Surgical ProceduresOrbitPeripheral Vascular DiseasesPhlebographyRetrospective StudiesSclerotherapyTomography, X-Ray ComputedTreatment OutcomeVeinsConceptsDeep orbital lesionsCarbon dioxide laser ablationOrbital lesionsAlcohol sclerotherapySurgical excisionFollow-upSudden onset of proptosisGuglielmi detachable coil embolizationMean follow-upDetachable coil embolizationSecondary to thrombosisGuglielmi detachable coilsRetrospective reviewRadiological evidenceCoil embolizationComplete resolutionEndovascular treatmentHistopathological featuresInvasive proceduresSurgical exposureDetachable coilsSudden onsetPatientsInvasive methodLesions
2003
Orbitofrontal Cholesterol Granuloma
Arat Y, Chaudhry I, Boniuk M. Orbitofrontal Cholesterol Granuloma. Ophthalmic Plastic And Reconstructive Surgery 2003, 19: 382-387. PMID: 14506423, DOI: 10.1097/01.iop.0000083644.62765.70.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overCholesterolExophthalmosFemaleFrontal BoneGiant Cells, Foreign-BodyGranuloma, Foreign-BodyHumansMagnetic Resonance ImagingMaleMiddle AgedOphthalmologic Surgical ProceduresOrbital DiseasesPostoperative ComplicationsRetrospective StudiesTomography, X-Ray ComputedTreatment OutcomeConceptsOrbitofrontal cholesterol granulomaCholesterol granulomaSoft tissue massLytic lesionsExtraconal soft tissue massLow incidence of recurrenceCase of cholesterol granulomaTissue massNon-contrast-enhancing lesionIncidence of recurrenceAssociated soft tissue massT2-weighted imagesOrbital cholesterol granulomaMagnetic resonance imagingSubbrow incisionSurgical excisionLateral orbitotomyRecurrent symptomsSinus explorationOrbital extensionRadiological featuresCystic lesionsHistopathological findingsFrontal mucoceleMean ageIncidental Diagnosis of Orbital Lymphoma During Blepharoplasty
Arat Y, Boniuk M. Incidental Diagnosis of Orbital Lymphoma During Blepharoplasty. Ophthalmic Plastic And Reconstructive Surgery 2003, 19: 316-319. PMID: 12878882, DOI: 10.1097/01.iop.0000077085.58437.81.Peer-Reviewed Original ResearchConceptsDiagnosis of orbital lymphomaOrbital lymphomaTime of surgeryIncidental diagnosisUpper blepharoplastyTreated with external beam radiotherapyB-cell lymphocytic lymphomaEvidence of systemic involvementBilateral ptosis repairBilateral upper blepharoplastyExternal beam radiotherapyPostoperative CT scansTime of blepharoplastyUnusual appearanceBilateral dermatochalasisBeam radiotherapyLymphocytic lymphomaPtosis repairBilateral ptosisRetrospective reviewOrbital fatPreaponeurotic fatCT scanSystem involvementLacrimal fossa