2024
Cell-Free Fat Extract with Anti-melanogenic Property Improves the Appearance of Infraorbital Dark Circles: A Preliminary Clinical Study
Kang B, Cai Y, Jia Z, Yao L, Gu J, Li W, Zhang W. Cell-Free Fat Extract with Anti-melanogenic Property Improves the Appearance of Infraorbital Dark Circles: A Preliminary Clinical Study. Aesthetic Plastic Surgery 2024, 1-10. PMID: 39532743, DOI: 10.1007/s00266-024-04445-9.Peer-Reviewed Original ResearchCell-free fat extractInfraorbital dark circlesDark circlesFollow-upLevel of Evidence IVThis journalEvidence-Based Medicine ratingsPreliminary clinical studiesLevel of evidenceStatistically significant improvementIVThis journalClinical studiesIntradermal injectionClinical trialsPeriocular wrinklesClinical trial assessmentEvaluation of skin colorEffective treatmentMelanin contentConclusionOur studyPatientsTreatmentInhibited melanin synthesisOnline InstructionsZebrafish embryosSignificant improvement
2023
Intradermal Local Injection of Autologous Cell‐Free Fat Extract for the Treatment of Refractory Postinflammatory Hyperpigmentation
Cai Y, Jia Z, Gu J, Kang B, Zheng H, Li W, Zhang W. Intradermal Local Injection of Autologous Cell‐Free Fat Extract for the Treatment of Refractory Postinflammatory Hyperpigmentation. Dermatologic Therapy 2023, 2023 DOI: 10.1155/2023/9561809.Peer-Reviewed Original ResearchCell-free fat extractTreatment of PIHPostinflammatory hyperpigmentationTreatment-related adverse eventsMonths of treatmentCurrent treatment modalitiesTransepidermal water lossAdverse eventsSerious complicationsTreatment modalitiesIntradermal injectionLocal injectionEfficacy assessmentFat extractTwo-week intervalsPatientsLesion colorSubjective parametersTreatmentSignificant reductionHyperpigmentationInjectionBS indexSkin lightnessSignificant improvement