Removal of batch effects using distribution-matching residual networks
Shaham U, Stanton KP, Zhao J, Li H, Raddassi K, Montgomery R, Kluger Y. Removal of batch effects using distribution-matching residual networks. Bioinformatics 2017, 33: 2539-2546. PMID: 28419223, PMCID: PMC5870543, DOI: 10.1093/bioinformatics/btx196.Peer-Reviewed Original ResearchConceptsMeasurement errorNovel deep learning approachRandom measurement errorMultivariate distributionsResidual neural networkDeep learning approachNovel biological technologiesMaximum mean discrepancyPhysical phenomenaResidual networkNeural networkLearning approachSystematic componentSupplementary dataSystematic errorsMean discrepancyScRNA-seq datasetsBatch effectsErrorNetworkStatistical analysis