Diagnostic values of BALF metagenomic next-generation sequencing, BALF real-time PCR and serum BDG for Pneumocystis jirovecii pneumonia in HIV-infected patients
Chen Q, Chen X, Mo P, Chen L, Du Q, Hu W, Jiang Q, Zhang Z, Zhang Y, Guo Q, Xiong Y, Deng L. Diagnostic values of BALF metagenomic next-generation sequencing, BALF real-time PCR and serum BDG for Pneumocystis jirovecii pneumonia in HIV-infected patients. Frontiers In Microbiology 2024, 15: 1421660. PMID: 39372273, PMCID: PMC11449763, DOI: 10.3389/fmicb.2024.1421660.Peer-Reviewed Original ResearchPneumocystis jirovecii pneumoniaMetagenomic next-generation sequencingBronchoalveolar lavage fluidHuman immunodeficiency virusReal-time polymerase chain reactionHIV-infected patientsSerum BDGPolymerase chain reactionCo-pathogensPJP patientsP. jiroveciiBronchoalveolar lavage fluid metagenomic next-generation sequencingDiagnostic performance of metagenomic next-generation sequencingDiagnostic value of bronchoalveolar lavage fluidSpecificity of metagenomic next-generation sequencingDiagnosis of Pneumocystis jirovecii pneumoniaAntimicrobial treatmentPerformance of metagenomic next-generation sequencingDose of trimethoprim-sulfamethoxazolePneumocystis jirovecii pneumonia patientDiagnostic valueNext-generation sequencingModification of antimicrobial treatmentMetagenomic next-generation sequencing resultsClinical final diagnosis