2023
Cab45 deficiency leads to the mistargeting of progranulin and prosaposin and aberrant lysosomal positioning
Tran M, Tüshaus J, Kim Y, Ramazanov B, Devireddy S, Lichtenthaler S, Ferguson S, von Blume J. Cab45 deficiency leads to the mistargeting of progranulin and prosaposin and aberrant lysosomal positioning. Traffic 2023, 24: 4-19. PMID: 36398980, PMCID: PMC9825660, DOI: 10.1111/tra.12873.Peer-Reviewed Original Research
2022
Ca2+-activated sphingomyelin scrambling and turnover mediate ESCRT-independent lysosomal repair
Niekamp P, Scharte F, Sokoya T, Vittadello L, Kim Y, Deng Y, Südhoff E, Hilderink A, Imlau M, Clarke CJ, Hensel M, Burd CG, Holthuis JCM. Ca2+-activated sphingomyelin scrambling and turnover mediate ESCRT-independent lysosomal repair. Nature Communications 2022, 13: 1875. PMID: 35388011, PMCID: PMC8986845, DOI: 10.1038/s41467-022-29481-4.Peer-Reviewed Original ResearchMeSH KeywordsCalciumCytosolEndosomal Sorting Complexes Required for TransportLysosomesSphingomyelinsConceptsSubsequent metabolic conversion