2022
Systematic Review and Meta-analysis: Task-based fMRI Studies in Youths With Irritability
Lee KS, Hagan CN, Hughes M, Cotter G, Freud E, Kircanski K, Leibenluft E, Brotman MA, Tseng WL. Systematic Review and Meta-analysis: Task-based fMRI Studies in Youths With Irritability. Journal Of The American Academy Of Child & Adolescent Psychiatry 2022, 62: 208-229. PMID: 35944754, PMCID: PMC9892288, DOI: 10.1016/j.jaac.2022.05.014.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingFMRI studyNeurocognitive functionNeural convergenceActivation likelihood estimationLow frustration toleranceIrritability measuresFrequent temper tantrumsSample characteristicsCognitive controlFMRI taskEmotional reactivityStimulus typeFMRI resultsChildhood irritabilityFrustration toleranceNeural mechanismsFunctional neuroimagingTransdiagnostic symptomsTask domainTemper tantrumsFMRI methodsNeuroscience databasesNull findingsCoordinate-based data
2017
Test-retest reliability and validity of a frustration paradigm and irritability measures
Tseng WL, Moroney E, Machlin L, Roberson-Nay R, Hettema JM, Carney D, Stoddard J, Towbin KA, Pine DS, Leibenluft E, Brotman MA. Test-retest reliability and validity of a frustration paradigm and irritability measures. Journal Of Affective Disorders 2017, 212: 38-45. PMID: 28135689, PMCID: PMC8049456, DOI: 10.1016/j.jad.2017.01.024.Peer-Reviewed Original ResearchConceptsTest-retest reliabilityParent-reported irritabilityIrritability measuresGood test-retest reliabilityNegative affectIrritability ScaleValidity of assessmentsBehavioral paradigmsChild irritabilityTreatment researchGeneral population sampleConvergent validityExcellent test-retest reliabilityModest supportConstruct validityTaskParticipantsIrritabilityParadigmIntraclass correlation