Featured Publications
A primer for quantum computing and its applications to healthcare and biomedical research
Durant T, Knight E, Nelson B, Dudgeon S, Lee S, Walliman D, Young H, Ohno-Machado L, Schulz W. A primer for quantum computing and its applications to healthcare and biomedical research. Journal Of The American Medical Informatics Association 2024, 31: 1774-1784. PMID: 38934288, PMCID: PMC11258415, DOI: 10.1093/jamia/ocae149.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2022
Automated multilabel diagnosis on electrocardiographic images and signals
Sangha V, Mortazavi BJ, Haimovich AD, Ribeiro AH, Brandt CA, Jacoby DL, Schulz WL, Krumholz HM, Ribeiro ALP, Khera R. Automated multilabel diagnosis on electrocardiographic images and signals. Nature Communications 2022, 13: 1583. PMID: 35332137, PMCID: PMC8948243, DOI: 10.1038/s41467-022-29153-3.Peer-Reviewed Original ResearchConceptsConvolutional neural networkArtificial intelligenceApplication of AISignal-based dataSignal-based modelElectrocardiographic imagesECG imagesGrad-CAMImage-based modelsNeural networkDiagnosis modelECG signalsImagesClinical labelsValidation setLabelsExternal validation setMultilabelIntelligenceNetworkApplicationsModelBroad useSetBroader setting
2016
Gene therapy applications to transfusion medicine
Gehrie E, Bersenev A, Bruscia E, Krause D, Schulz W. Gene therapy applications to transfusion medicine. 2016, 452-455. DOI: 10.1002/9781119013020.ch38.ChaptersGene therapyTherapeutic genetic materialGene therapy applicationsTranscription activator-like effector nucleasesZinc finger nucleasesPackaging cell lineGene-modified cellsGene-editing approachesNonviral techniquesTherapy applicationsFinger nucleasesEffector nucleasesViral vectorsShort palindromic repeatsVector systemReplication-competent virusPalindromic repeatsHemophilia BPossible applicationsGenetic materialNucleaseApplicationsGenetic diseasesFactor IXVector