1973
The Use of Drugs in Combination for the Treatment of Cancer — Rationale and Results
DeVita V, Schein P. The Use of Drugs in Combination for the Treatment of Cancer — Rationale and Results. New England Journal Of Medicine 1973, 288: 998-1006. PMID: 4348752, DOI: 10.1056/nejm197305102881905.Peer-Reviewed Original ResearchAnimalsAntineoplastic AgentsBreast NeoplasmsChildDose-Response Relationship, DrugDrug ResistanceDrug SynergismFemaleGastrointestinal NeoplasmsHodgkin DiseaseHumansLeukemia L1210Leukemia, LymphoidLeukemia, Myeloid, AcuteLymphomaMaleModels, BiologicalNeoplasmsNeuroblastomaRemission, SpontaneousTesticular NeoplasmsTime FactorsWilms Tumor
1972
Clinical study with bleomycin: Tolerance to twice weekly dosage
Ohnuma T, Selawry O, Holland J, DeVita V, Shedd D, Hansen H, Muggia F. Clinical study with bleomycin: Tolerance to twice weekly dosage. Cancer 1972, 30: 914-922. PMID: 4116909, DOI: 10.1002/1097-0142(197210)30:4<914::aid-cncr2820300409>3.0.co;2-8.Peer-Reviewed Original ResearchConceptsSquamous cell carcinomaCell carcinomaDose levelsObjective tumor responseBody surface areaTherapeutic dose levelsOptimal dose levelNew antineoplastic agentsPulmonary infiltratesTransient hypertensionUrinary burningAbdominal distentionComplete remissionHematologic toxicityCutaneous toxicityWeekly dosesProlonged courseAdditional patientsPatient toleranceSkin toxicityMalignant neoplasmsTesticular carcinomaTumor responseTumor regressionWeekly dosageLate Recurrence of Testicular Tumor
Chabner B, Canellos G, Olweny C, DeVita V. Late Recurrence of Testicular Tumor. New England Journal Of Medicine 1972, 287: 413. PMID: 5065110, DOI: 10.1056/nejm197208242870817.Peer-Reviewed Original Research