2016
The Sweet Path to Metabolic Demise: Fructose and Lipid Synthesis
Herman MA, Samuel VT. The Sweet Path to Metabolic Demise: Fructose and Lipid Synthesis. Trends In Endocrinology And Metabolism 2016, 27: 719-730. PMID: 27387598, PMCID: PMC5035631, DOI: 10.1016/j.tem.2016.06.005.Peer-Reviewed Original ResearchConceptsFructose consumptionHepatic fructose metabolismHepatic insulin resistanceImpairment of insulinDe novo lipogenesisHepatic steatosisInsulin resistanceEpidemiological studiesNovo lipogenesisMetabolic diseasesFructose metabolismLipogenic enzymesLipogenesisFatty acid synthesisKey transcription factorDiseaseAldolase BLipid synthesisAdditional mechanismHypertriglyceridemiaSteatosisTranscription factorsTherapyInsulinImpairment
2010
Standard operating procedures for describing and performing metabolic tests of glucose homeostasis in mice
Ayala JE, Consortium F, Samuel V, Morton G, Obici S, Croniger C, Shulman G, Wasserman D, McGuinness O. Standard operating procedures for describing and performing metabolic tests of glucose homeostasis in mice. Disease Models & Mechanisms 2010, 3: 525-534. PMID: 20713647, PMCID: PMC2938392, DOI: 10.1242/dmm.006239.Peer-Reviewed Original Research