2020
Cardiovascular severe maternal morbidity in pregnant and postpartum women: development and internal validation of risk prediction models
Malhamé I, Danilack V, Raker C, Hardy E, Spalding H, Bouvier B, Hurlburt H, Vrees R, Savitz D, Mehta N. Cardiovascular severe maternal morbidity in pregnant and postpartum women: development and internal validation of risk prediction models. BJOG An International Journal Of Obstetrics & Gynaecology 2020, 128: 922-932. PMID: 32946639, DOI: 10.1111/1471-0528.16512.Peer-Reviewed Original ResearchConceptsSevere maternal morbidityMaternal morbidityRisk prediction modelDelivery hospitalisationChronic hypertensionGestational hypertensionMaternal ageInternal validationPostpartum modelNon-Hispanic black race/ethnicityBlack race/ethnicityObstetric teaching hospitalAcute heart failureRetrospective cohort studyPoor pregnancy outcomesValvular heart diseaseStrongest predictorRace/ethnicityRisk assessment toolCardiogenic shockSevere hypertensionCohort studyMultiple gestationsPregnancy outcomesHeart failureIdentifying cardiovascular severe maternal morbidity in epidemiologic studies
Malhamé I, Mehta N, Raker C, Hardy E, Spalding H, Bouvier B, Savitz D, Danilack V. Identifying cardiovascular severe maternal morbidity in epidemiologic studies. Paediatric And Perinatal Epidemiology 2020, 34: 452-459. PMID: 31971615, DOI: 10.1111/ppe.12571.Peer-Reviewed Original ResearchMeSH KeywordsAdultDelivery, ObstetricElectric CountershockEpidemiologic StudiesFemaleHeart ArrestHospitalizationHumansInternational Classification of DiseasesMaternal MortalityOutcome Assessment, Health CarePre-EclampsiaPregnancyPregnancy Complications, CardiovascularPregnancy, High-RiskSensitivity and SpecificitySeverity of Illness IndexConceptsSevere maternal morbidityMaternal morbiditySevere preeclampsiaEpidemiologic studiesICD codesDelivery hospitalisationPredictive valueObstetric teaching hospitalAcute myocardial infarctionNegative predictive valuePositive predictive valueRandom sampleComposite variableCardiac arrestMaternal mortalityMyocardial infarctionTeaching hospitalAdministrative data setsHigh riskHospitalisationPreeclampsiaDisease controlMorbidityExpert cliniciansStandardised tools
2011
Association between sclerostin and bone density in chronic spinal cord injury
Morse L, Sudhakar S, Danilack V, Tun C, Lazzari A, Gagnon D, Garshick E, Battaglino R. Association between sclerostin and bone density in chronic spinal cord injury. Journal Of Bone And Mineral Research 2011, 27: 352-359. PMID: 22006831, PMCID: PMC3288145, DOI: 10.1002/jbmr.546.Peer-Reviewed Original ResearchConceptsChronic spinal cord injurySpinal cord injuryHigher sclerostin levelsSclerostin levelsBone lossCord injuryMechanical unloadingBone densityRodent modelsComplete spinal cord injuryOngoing bone lossParalyzed lower extremitiesBone formationLevels of sclerostinProfound bone lossBone mineral contentGood therapeutic targetChronic paraplegiaMuscle paralysisLower extremitiesOsteoporosis severityShort-term studiesTherapeutic targetAnimal modelsSclerostin