2019
Lifting Each Other Up: Epidermal Stem Cells in Tissue Homeostasis
Horsley V. Lifting Each Other Up: Epidermal Stem Cells in Tissue Homeostasis. Developmental Cell 2019, 51: 296-298. PMID: 31689385, DOI: 10.1016/j.devcel.2019.10.013.Peer-Reviewed Original Research
2012
Development and homeostasis of the sebaceous gland
Niemann C, Horsley V. Development and homeostasis of the sebaceous gland. Seminars In Cell And Developmental Biology 2012, 23: 928-936. PMID: 22960253, PMCID: PMC5595243, DOI: 10.1016/j.semcdb.2012.08.010.Peer-Reviewed Original ResearchConceptsDistinct signaling pathwaysSebaceous gland biologyLipid composition resultsLineage differentiationSignaling pathwaysGland developmentNormal developmentSkin homeostasisMammalian skinEpidermal appendagesTumor formationCell linesCurrent knowledgeDifferentiationCrucial mediatorLipid metabolismAtrophic sebaceous glandsNew insightsVivo mechanismsHomeostasisSebaceous glandsAbnormal proliferationSebaceous gland developmentProliferationImportant role
2006
Blimp1 Defines a Progenitor Population that Governs Cellular Input to the Sebaceous Gland
Horsley V, O'Carroll D, Tooze R, Ohinata Y, Saitou M, Obukhanych T, Nussenzweig M, Tarakhovsky A, Fuchs E. Blimp1 Defines a Progenitor Population that Governs Cellular Input to the Sebaceous Gland. Cell 2006, 126: 597-609. PMID: 16901790, PMCID: PMC2424190, DOI: 10.1016/j.cell.2006.06.048.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornBromodeoxyuridineCell CountCell DifferentiationCell LineageCell MovementCell ProliferationCells, CulturedEpithelial CellsGene Expression Regulation, DevelopmentalHair FollicleHyperplasiaMiceMice, KnockoutMice, TransgenicMultipotent Stem CellsPositive Regulatory Domain I-Binding Factor 1Proto-Oncogene Proteins c-mycRepressor ProteinsSebaceous GlandsStem CellsTranscription FactorsConceptsMultipotent stem cellsCellular inputsGenetic lineage tracingStem cellsUnipotent progenitor cellsTranscriptional repressor Blimp1Stem cell activityElevated c-myc expressionLineage commitmentC-myc expressionBrdU-labeling experimentsLineage tracingProgenitor populationsLineagesBlimp1Progenitor cellsCell proliferationLabeling experimentsSebaceous glandsCellsCell culture studiesSG homeostasisHair folliclesHomeostasisGland