2013
Kinesin 5B (KIF5B) Is Required for Progression through Female Meiosis and Proper Chromosomal Segregation in Mitotic Cells
Kidane D, Sakkas D, Nottoli T, McGrath J, Sweasy JB. Kinesin 5B (KIF5B) Is Required for Progression through Female Meiosis and Proper Chromosomal Segregation in Mitotic Cells. PLOS ONE 2013, 8: e58585. PMID: 23560038, PMCID: PMC3613343, DOI: 10.1371/journal.pone.0058585.Peer-Reviewed Original ResearchConceptsMitotic cell divisionCell divisionKinesin 5BChromosomal segregationMitotic cellsCell developmentGerminal vesicle breakdownKnockdown of KIF5BProper chromosomal segregationChromosomal segregation defectsFemale meiosisSegregation defectsChromosomal stabilityRNA interferenceChromosomal instabilityFirst polar bodyMouse oocytesKIF5BMolecular motorsPolar bodyVesicle breakdownBirth defectsDivisionCellsMeiosis
2008
Chimeric mice reveal clonal development of pancreatic acini, but not islets
Swenson ES, Xanthopoulos J, Nottoli T, McGrath J, Theise ND, Krause DS. Chimeric mice reveal clonal development of pancreatic acini, but not islets. Biochemical And Biophysical Research Communications 2008, 379: 526-531. PMID: 19116141, PMCID: PMC2657659, DOI: 10.1016/j.bbrc.2008.12.104.Peer-Reviewed Original ResearchConceptsStem/progenitor cellsMultiple progenitorsAdult mouse small intestineMale ES cellsProgenitor cellsFemale blastocystsCrypt stem cellsClonal descendantsES cellsY chromosomeChimeric miceFemale cellsIntestinal crypt stem cellsExocrine pancreatic aciniFemale epithelial cellsClonal developmentStem cellsSitu hybridizationMouse small intestineEpithelial cellsIntestinal cryptsProgenitorsPancreatic aciniCellsPancreatic islets