2023
Warm autoantibodies mimicking alloantibodies: Three cases of autoantibodies with unusual antigenic specificity
Jacobs J, Binns T, Abels E, Campos J, Elkabbani R, Kress A, Sostin N, Tormey C. Warm autoantibodies mimicking alloantibodies: Three cases of autoantibodies with unusual antigenic specificity. American Journal Of Clinical Pathology 2023, 160: 561-565. PMID: 37598315, DOI: 10.1093/ajcp/aqad095.Peer-Reviewed Original ResearchConceptsWarm autoantibodiesRed blood cellsAntigenic specificityCase of autoantibodiesCase 1Autoimmune hemolytic anemiaDirect antiglobulin testRBC transfusionPregnant womenTransfusion reactionsAntiglobulin testHemolytic anemiaAutoantibodiesRBC antigensAntibody detectionRBC unitsRare reportsBlood cellsCase 2Immunohematologic testingSignificant hemolysisRhD typingCase 3AlloantibodiesAutoantiEpidemiological and clinical features, therapeutic strategies and outcomes in patients with hyperhaemolysis: A systematic review
Jacobs J, Stephens L, Allen E, Binns T, Booth G, Hendrickson J, Karafin M, Tormey C, Woo J, Adkins B. Epidemiological and clinical features, therapeutic strategies and outcomes in patients with hyperhaemolysis: A systematic review. British Journal Of Haematology 2023, 201: 1025-1032. PMID: 37074146, DOI: 10.1111/bjh.18825.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSickle cell diseaseHyperhaemolysis syndromeAnti-globulin testRed blood cellsSupportive transfusionsIndirect anti-globulin testDirect anti-globulin testIntravenous immune globulinHaemolytic transfusion reactionsImmune globulinMedian hemoglobinClinical featuresCommon therapyUnderlying pathophysiologyTransfusion reactionsCell diseaseSevere formTherapeutic strategiesPatientsSystematic reviewBlood cellsTransfusionHyperhaemolysisDaysCorticosteroidsWarm autoimmune hemolytic anemia with anti‐Jka specificity following babesiosis masquerading as a delayed hemolytic transfusion reaction
Jacobs J, Abels E, Binns T, Tormey C, Sostin N. Warm autoimmune hemolytic anemia with anti‐Jka specificity following babesiosis masquerading as a delayed hemolytic transfusion reaction. Transfusion 2023, 63: 872-876. PMID: 36648131, DOI: 10.1111/trf.17252.Peer-Reviewed Case Reports and Technical NotesConceptsWarm autoimmune hemolytic anemiaDirect antiglobulin testAutoimmune hemolytic anemiaHemolytic transfusion reactionsRed blood cellsRBC transfusionTransfusion reactionsHemolytic anemiaKidd antigensPositive direct antiglobulin testDevelopment of autoantibodiesBabesia microti infectionImmunohematology reference laboratoryColumn agglutination technologyAnti-JkUndetectable parasitemiaAutoantibody statusWarm autoantibodiesRBC antibodiesMicroti infectionAntiglobulin testAntigen specificityAutoantibodiesHealthcare providersAntibody detection
2022
State of the Evidence: Drug Removal via Apheresis
Binns T, Sostin N, Tormey C. State of the Evidence: Drug Removal via Apheresis. Transfusion Medicine Reviews 2022, 37: 16-20. PMID: 36604194, DOI: 10.1016/j.tmrv.2022.12.003.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAlloimmunization following antigen‐negative red blood cell transfusion
Jacobs J, Binns T, Abels E, Iyer K, Villalba C, Verma A, Sostin N, Tormey C. Alloimmunization following antigen‐negative red blood cell transfusion. Transfusion 2022, 63: 430-434. PMID: 36458330, DOI: 10.1111/trf.17208.Peer-Reviewed Case Reports and Technical NotesMeSH KeywordsBlood Group AntigensBlood TransfusionErythrocyte TransfusionErythrocytesFemaleHumansIsoantibodiesPregnancyConceptsTransfusion of RBCsRed blood cell transfusionRed blood cell alloimmunizationPrevious antigen exposureBlood cell transfusionAlloantibody specificitiesCell transfusionRBC transfusionAntigen exposureRBC alloantibodiesAntigenic stimulusDetectable titersAntigenic stimulationMyeloid neoplasmsTransfusionAlloantibodiesAlloimmunizationParticular antigenPrior exposureStimulatory eventsExact mechanismCorresponding antibodiesRBCsExposurePregnancy