2016
Assessing Local Risk of Rifampicin-Resistant Tuberculosis in KwaZulu-Natal, South Africa Using Lot Quality Assurance Sampling
Heidebrecht CL, Podewils LJ, Pym A, Mthiyane T, Cohen T. Assessing Local Risk of Rifampicin-Resistant Tuberculosis in KwaZulu-Natal, South Africa Using Lot Quality Assurance Sampling. PLOS ONE 2016, 11: e0153143. PMID: 27050561, PMCID: PMC4822784, DOI: 10.1371/journal.pone.0153143.Peer-Reviewed Original ResearchConceptsIncident TB casesTB casesResistant TBDrug-resistant TB casesRifampicin-resistant tuberculosisMultidrug-resistant tuberculosisDrug susceptibility testingRIF-resistant TBLot Quality Assurance SamplingQuality assurance samplingResistant diseaseHigh burdenRIF resistanceKwaZulu-NatalSusceptibility testingHigh-risk areasTuberculosisRiskGreater proportionBurdenTBDiseaseGeographic heterogeneityCasesRifampicin
2008
Are Survey-Based Estimates of the Burden of Drug Resistant TB Too Low? Insight from a Simulation Study
Cohen T, Colijn C, Finklea B, Wright A, Zignol M, Pym A, Murray M. Are Survey-Based Estimates of the Burden of Drug Resistant TB Too Low? Insight from a Simulation Study. PLOS ONE 2008, 3: e2363. PMID: 18523659, PMCID: PMC2408555, DOI: 10.1371/journal.pone.0002363.Peer-Reviewed Original ResearchConceptsResistant tuberculosisIncident casesTotal burdenDrug-resistant TBDrug-resistant tuberculosisSecond-line antibioticsDrug treatment regimensDrug sensitivity testingDrug-resistant strainsBurden of resistanceEmergence of tuberculosisResistant TBTreatment regimensPrevalent casesWorldwide burdenIntroduction of interventionsRoutine surveillanceSurveillance strategiesDrug resistanceTuberculosisLaboratory capacityMycobacterium tuberculosisSensitivity testingTuberculosis modelBurden