Modeling the effects of strain diversity and mechanisms of strain competition on the potential performance of new tuberculosis vaccines
Cohen T, Colijn C, Murray M. Modeling the effects of strain diversity and mechanisms of strain competition on the potential performance of new tuberculosis vaccines. Proceedings Of The National Academy Of Sciences Of The United States Of America 2008, 105: 16302-16307. PMID: 18849476, PMCID: PMC2570977, DOI: 10.1073/pnas.0808746105.Peer-Reviewed Original ResearchConceptsNew tuberculosis vaccinesTuberculosis vaccineBacillus Calmette-Guérin (BCG) vaccinationCurrent vaccine candidatesM. tuberculosis strainsPerformance of vaccinesTuberculosis infectionTuberculosis controlStrain diversityMass vaccinationVaccine candidatesNew vaccinesTuberculosis strainsStrain replacementVaccineM. tuberculosisMycobacterium tuberculosisTransmission of diseaseVaccinationTuberculosisInfectionDiseaseStrain specificityPotential effectsMorbidity