2020
Perceived burdensomeness and neural responses to ostracism in the Cyberball task
Le TM, Zhornitsky S, Wang W, Li CR. Perceived burdensomeness and neural responses to ostracism in the Cyberball task. Journal Of Psychiatric Research 2020, 130: 1-8. PMID: 32763557, PMCID: PMC7554229, DOI: 10.1016/j.jpsychires.2020.06.015.Peer-Reviewed Original ResearchConceptsCyberball taskInterpersonal needsIndividual differencesProsocial behaviorNeural responsesSocial interactionStronger neural responsesGreater brain activationDorsomedial prefrontal cortexMiddle frontal gyrusSocial exclusionResponse timeBrain activationBrain correlatesBehavioral performanceFMRI studyAnterior insulaFrontal gyrusSocial painBehavioral avoidanceAffective responsesBehavioral measuresNeural activationPrefrontal cortexEmotional distress
2019
Posterior Cingulate Cortical Response to Active Avoidance Mediates the Relationship between Punishment Sensitivity and Problem Drinking
Le TM, Zhornitsky S, Wang W, Ide J, Zhang S, Li CR. Posterior Cingulate Cortical Response to Active Avoidance Mediates the Relationship between Punishment Sensitivity and Problem Drinking. Journal Of Neuroscience 2019, 39: 6354-6364. PMID: 31189577, PMCID: PMC6687909, DOI: 10.1523/jneurosci.0508-19.2019.Peer-Reviewed Original ResearchConceptsPosterior cingulate cortexMaladaptive coping mechanismPunishment sensitivityNeural substratesBehavioral avoidanceResponse inhibitionNegative affectAlcohol usePosterior cingulate cortex activationCoping mechanismsProblem drinkingAlcohol misusePCC responseSensation-seeking traitsAvoidance strategiesAlcohol Use Disorders Identification TestHazardous alcohol useAvoidance tendenciesAlcohol Use Disorders Identification Test (AUDIT) scoresGo taskNeural processesReward QuestionnaireAction inhibitionBrain activationCerebral correlates