2019
Open versus Endovascular Repair of Abdominal Aortic Aneurysm
Lederle FA, Kyriakides TC, Stroupe KT, Freischlag JA, Padberg FT, Matsumura JS, Huo Z, Johnson GR. Open versus Endovascular Repair of Abdominal Aortic Aneurysm. New England Journal Of Medicine 2019, 380: 2126-2135. PMID: 31141634, DOI: 10.1056/nejmoa1715955.Peer-Reviewed Original ResearchConceptsEndovascular repair groupOpen repair groupEndovascular repairOpen repairOverall survivalAbdominal aortic aneurysmEuropean trialsAortic aneurysmLong-term overall survivalChronic obstructive lung diseaseWorse long-term outcomesAsymptomatic abdominal aortic aneurysmElective endovascular repairLow perioperative mortalityObstructive lung diseaseTraditional open repairAbdominal aortic aneurysms resultsLong-term outcomesLong-term resultsNumber of patientsLong-term survivalCause mortalityPerioperative mortalityPerioperative periodMore patients
2015
Predictors and outcomes of endoleaks in the Veterans Affairs Open Versus Endovascular Repair (OVER) Trial of Abdominal Aortic Aneurysms
Lal BK, Zhou W, Li Z, Kyriakides T, Matsumura J, Lederle FA, Freischlag J, Group O. Predictors and outcomes of endoleaks in the Veterans Affairs Open Versus Endovascular Repair (OVER) Trial of Abdominal Aortic Aneurysms. Journal Of Vascular Surgery 2015, 62: 1394-1404. PMID: 26598115, DOI: 10.1016/j.jvs.2015.02.003.Peer-Reviewed Original ResearchConceptsType II endoleakEndovascular repairSecondary interventionsAortic aneurysmRisk factorsAneurysm sizeVeterans AffairsKaplan-Meier survival analysisInitial aneurysm sizeStandard-risk patientsSuccessful endovascular repairType of endoleakVascular risk factorsInfrarenal aortic aneurysmLong-term outcomesAnalysis of patientsLength of survivalAbdominal aortic aneurysmPresence of endoleaksLogistic regression analysisDiameter enlargementOVER trialPatient demographicsEndoleak developmentLong follow
2012
Long-Term Comparison of Endovascular and Open Repair of Abdominal Aortic Aneurysm
Lederle FA, Freischlag JA, Kyriakides TC, Matsumura JS, Padberg FT, Kohler TR, Kougias P, Jean-Claude JM, Cikrit DF, Swanson KM. Long-Term Comparison of Endovascular and Open Repair of Abdominal Aortic Aneurysm. New England Journal Of Medicine 2012, 367: 1988-1997. PMID: 23171095, DOI: 10.1056/nejmoa1207481.Peer-Reviewed Original ResearchConceptsEndovascular repair groupOpen repair groupAbdominal aortic aneurysmYears of ageEndovascular repairOpen repairLong-term survivalAortic aneurysmSimilar long-term survivalAsymptomatic abdominal aortic aneurysmVeterans Affairs Medical CenterElective endovascular repairLong-term morbidityTraditional open repairType of treatmentCause mortalityPerioperative mortalityTime of registrationOlder patientsYounger patientsEndovascular approachPrimary outcomeAneurysm ruptureMedical CenterSurvival advantage
2009
Outcomes Following Endovascular vs Open Repair of Abdominal Aortic Aneurysm: A Randomized Trial
Lederle FA, Freischlag JA, Kyriakides TC, Padberg FT, Matsumura JS, Kohler TR, Lin PH, Jean-Claude JM, Cikrit DF, Swanson KM, Peduzzi PN, Group F. Outcomes Following Endovascular vs Open Repair of Abdominal Aortic Aneurysm: A Randomized Trial. JAMA 2009, 302: 1535-1542. PMID: 19826022, DOI: 10.1001/jama.2009.1426.Peer-Reviewed Original ResearchMeSH KeywordsAgedAortic Aneurysm, AbdominalBlood Vessel Prosthesis ImplantationCatheterization, PeripheralErectile DysfunctionFemaleHumansKaplan-Meier EstimateLength of StayMaleMiddle AgedMinimally Invasive Surgical ProceduresMorbidityPostoperative ComplicationsProportional Hazards ModelsQuality of LifeConceptsAbdominal aortic aneurysmOpen repairShort-term outcomesEndovascular repairPerioperative mortalityMajor morbidityAortic aneurysmProcedure failureTherapeutic proceduresIntensive care unit stayLong-term outcome dataVeterans Affairs Medical CenterElective endovascular repairEndovascular repair groupHealth-related qualityTraditional open repairElective AAA repairMedian procedure timeLength of stayMulticenter clinical trialQuality of lifeElective endovascularTransfusion requirementsUnit stayHospital stay