Featured Publications
Subcellular progression of mesenchymal transition identified by two discrete synchronous cell lines derived from the same glioblastoma
Kim S, Park S, Chowdhury T, Hong J, Ahn J, Jeong T, Yu H, Shin Y, Ku J, Park J, Hur J, Lee H, Kim K, Park C. Subcellular progression of mesenchymal transition identified by two discrete synchronous cell lines derived from the same glioblastoma. Cellular And Molecular Life Sciences 2022, 79: 181. PMID: 35278143, PMCID: PMC8918182, DOI: 10.1007/s00018-022-04188-3.Peer-Reviewed Original ResearchConceptsMesenchymal transitionCell linesAvailable single-cell RNA-seq dataMesenchymal transition (EMT) processCancer cell linesSame tissue samplesTherapeutic implicationsTumor samplesRecurrent samplesDriver mutationsGlioblastomaTissue samplesDistinct cancer cell linesGBM samplesIntratumoral heterogeneityTranscriptomic characteristics
2020
Penta-fluorophenol: a Smiles rearrangement-inspired cysteine-selective fluorescent probe for imaging of human glioblastoma
An J, Kang S, Huh E, Kim Y, Lee D, Jo H, Joung J, Kim V, Lee J, Dho Y, Jung Y, Hur J, Park C, Jung J, Huh Y, Ku J, Kim S, Chowdhury T, Park S, Kang J, Oh M, Park C, Kim D. Penta-fluorophenol: a Smiles rearrangement-inspired cysteine-selective fluorescent probe for imaging of human glioblastoma. Chemical Science 2020, 11: 5658-5668. PMID: 32874505, PMCID: PMC7449700, DOI: 10.1039/d0sc01085e.Peer-Reviewed Original ResearchLong-term toxicitySpecific diagnostic proceduresClinical biopsy samplesHuman-derived cellsImmune responseIndividual patientsMouse modelGlioblastoma patientsBiopsy samplesNew biomarkersClinical sitesDisease sitesHuman tissue samplesDiagnostic proceduresGBM cellsHuman glioblastomaTreatment progressTissue samplesClinical samplesCysteine levelsPatientsPrecision diagnosisPresent findingsGBMImaging