2015
Mitochondrial ROS Signaling in Organismal Homeostasis
Shadel GS, Horvath TL. Mitochondrial ROS Signaling in Organismal Homeostasis. Cell 2015, 163: 560-569. PMID: 26496603, PMCID: PMC4634671, DOI: 10.1016/j.cell.2015.10.001.Peer-Reviewed Original ResearchConceptsReactive oxygen speciesOrganismal homeostasisMitochondrial ROS signalingMitochondrial reactive oxygen speciesAdaptive physiological responsesROS signalingCellular differentiationMitochondrial oxygen consumptionOxidative phosphorylationPhysiological responsesOxygen speciesCentral roleHomeostasisEukaryotesOrganic fuel moleculesPhosphorylationMitochondriaMoleculesSignalingSpeciesATPDifferentiationPathwayGreater understandingRole
2006
Uncoupling protein 2/3 immunoreactivity and the ascending dopaminergic and noradrenergic neuronal systems: Relevance for volume transmission
Rivera A, Agnati LF, Horvath TL, Valderrama JJ, de La Calle A, Fuxe K. Uncoupling protein 2/3 immunoreactivity and the ascending dopaminergic and noradrenergic neuronal systems: Relevance for volume transmission. Neuroscience 2006, 137: 1447-1461. PMID: 16387447, DOI: 10.1016/j.neuroscience.2005.05.051.Peer-Reviewed Original ResearchConceptsConfocal laser microscopy analysisReactive oxygen species productionLaser microscopy analysisProtein 2/3Oxygen species productionUncouple oxidative phosphorylationOxidative phosphorylationATP synthesisProteinSpecies productionDouble immunolabelingImportant roleMicroscopy analysisPhosphorylationMitochondriaRegulationCell groupsPlastic changesLocalizationIslandsAnimal modelsMagnaTyrosine hydroxylaseNeuronal systems