2017
Host-related immunodeficiency in the development of multiple myeloma
Dosani T, Mailankody S, Korde N, Manasanch E, Bhutani M, Tageja N, Roschewski M, Kwok M, Kazandjian D, Costello R, Burton D, Zhang Y, Liewehr D, Steinberg SM, Maric I, Landgren O. Host-related immunodeficiency in the development of multiple myeloma. Leukemia & Lymphoma 2017, 59: 1127-1132. PMID: 28792255, PMCID: PMC6750254, DOI: 10.1080/10428194.2017.1361026.Peer-Reviewed Original ResearchConceptsMultiple myelomaLymphocyte subsetsCD57- subsetImmune biomarkersDevelopment of MMMyeloma precursor diseaseNK cell proportionNovel immune biomarkersProgression of SMMMultiparametric flow cytometrySMM patientsImmune changesImmune patternsClinical guidancePrecursor diseaseCell proportionFlow cytometryMGUSPotential markerImmunodeficiencySequential changesMyelomaPatientsPrecursor conditionsProgression
2015
The cellular immune system in myelomagenesis: NK cells and T cells in the development of MM and their uses in immunotherapies
Dosani T, Carlsten M, Maric I, Landgren O. The cellular immune system in myelomagenesis: NK cells and T cells in the development of MM and their uses in immunotherapies. Blood Cancer Journal 2015, 5: e306-e306. PMID: 25885426, PMCID: PMC4450330, DOI: 10.1038/bcj.2015.32.Peer-Reviewed Original ResearchConceptsDevelopment of MMMultiple myelomaT cellsImmune systemNatural killer T cellsRegulatory T cellsKiller T cellsNatural killer cellsConventional T cellsΓδ T cellsCellular immune systemImmune subsetsNK cellsKiller cellsPeripheral bloodUndetermined significanceImmune cellsMonoclonal gammopathyImmune componentsTumor evolutionBone marrowMyelomagenesisImmunotherapyPrecursor conditionsCurrent literature