Mechanisms involved in attenuated cardio-protective role of ischemic preconditioning in metabolic disorders
Rana A, Goyal N, Ahlawat A, Jamwal S, Reddy B, Sharma S. Mechanisms involved in attenuated cardio-protective role of ischemic preconditioning in metabolic disorders. Perfusion 2014, 30: 94-105. PMID: 24947460, DOI: 10.1177/0267659114536760.Peer-Reviewed Original ResearchMeSH KeywordsHumansIschemic Preconditioning, MyocardialMetabolic DiseasesMuscle ProteinsMyocardial InfarctionMyocardiumConceptsCalcitonin gene-related peptideIschemic preconditioningDiabetes mellitusMitochondrial permeability transition poreMito-KATP channelChronic diabetes mellitusGene-related peptideCardio-protective roleIschemia/reperfusionSub-lethal ischemiaGlycogen synthase kinase-3βSynthase kinase-3βCardioprotective effectsMyocardial damageMyocardial infarctionBlood supplyPart of heartMetabolic disordersInvolvement of PTENBeneficial effectsPTEN inhibitorKinase-3βPathological statesMellitusHyperlipidemia