2023
Bacillus Calmette–Guérin Vaccine Attenuates Haloperidol-Induced TD-like Behavioral and Neurochemical Alteration in Experimental Rats
Yedke N, Upadhayay S, Singh R, Jamwal S, Ahmad S, Kumar P. Bacillus Calmette–Guérin Vaccine Attenuates Haloperidol-Induced TD-like Behavioral and Neurochemical Alteration in Experimental Rats. Biomolecules 2023, 13: 1667. PMID: 38002349, PMCID: PMC10669047, DOI: 10.3390/biom13111667.Peer-Reviewed Original ResearchConceptsBCG vaccineTardive dyskinesiaOrofacial dyskinesiaNeurotransmitter levelsBacillus Calmette-Guérin (BCG) vaccineFirst-generation antipsychotic drugsManagement of TDOxidative stressLevels of HVACalmette-Guérin vaccineHyperkinetic movement disordersMajor pathophysiological mechanismsPro-apoptotic markersLong-term useBCG treatmentNeuroprotective effectsNeurochemical alterationsOrofacial dysfunctionPathophysiological mechanismsAntipsychotic medicationNeuromodulatory propertiesSuppress inflammationSingle administrationAntipsychotic drugsHaloperidol injection
2017
Animal Models of Tardive Dyskinesia
Datta S, Jamwal S, Akula K, Bansal P. Animal Models of Tardive Dyskinesia. 2017, 79-88. DOI: 10.1007/978-981-10-5981-0_6.Peer-Reviewed Original Research
2016
Tetrabenazine: Spotlight on Drug Review
Kaur N, Kumar P, Jamwal S, Deshmukh R, Gauttam V. Tetrabenazine: Spotlight on Drug Review. Annals Of Neurosciences 2016, 23: 176-185. PMID: 27721587, PMCID: PMC5043267, DOI: 10.1159/000449184.Peer-Reviewed Original ResearchTreatment of choreaHyperkinetic disorderOnly US FoodVesicular monoamine transporter 2Further clinical trialsMonoamine transporter 2Treatment of psychosisMechanism of actionClinical efficacyTardive dyskinesiaClinical trialsClinical studiesMonoamine storesTourette syndromeDrug AdministrationUS FoodHuntington's choreaChoreaTherapeutic potentialTetrabenazineTransporter 2Huntington's diseaseAdverse effectsLack of awarenessDisease
2015
Beneficial effects of lycopene against haloperidol induced orofacial dyskinesia in rats: Possible neurotransmitters and neuroinflammation modulation
Datta S, Jamwal S, Deshmukh R, Kumar P. Beneficial effects of lycopene against haloperidol induced orofacial dyskinesia in rats: Possible neurotransmitters and neuroinflammation modulation. European Journal Of Pharmacology 2015, 771: 229-235. PMID: 26712377, DOI: 10.1016/j.ejphar.2015.12.032.Peer-Reviewed Original ResearchConceptsOrofacial dyskinesiaHaloperidol treatmentChronic neuroleptic treatmentAbnormal involuntary movementsSevere side effectsNeuroinflammatory modulationNeuroleptic treatmentTardive dyskinesiaProtective effectInvoluntary movementsSide effectsDyskinesiaBiochemical parametersHaloperidolRatsTreatmentDaysLycopeneStriatum