2024
Nutraceuticals Unveiled a Multifaceted Neuroprotective Mechanisms for Parkinson’s Disease: Elixir for the Brain
Soni D, Jamwal S, Chawla R, Singh S, Singh D, Singh T, Khurana N, Kanwal A, Dureja H, Patil U, Singh R, Kumar P. Nutraceuticals Unveiled a Multifaceted Neuroprotective Mechanisms for Parkinson’s Disease: Elixir for the Brain. Food Reviews International 2024, 40: 3079-3102. DOI: 10.1080/87559129.2024.2337766.Peer-Reviewed Original ResearchPre-clinicalGut-brain axisProtein ubiquitinationParkinson's diseaseMitochondrial dysfunctionSignaling pathwayMolecular mechanismsRelieve PD symptomsSymptoms of PDClinical trialsHealth benefits of nutraceuticalsBenefits of nutraceuticalsCustomized therapyClinical aspectsExpression of PDMediterranean dietNeurotransmitter imbalanceNeuroprotective mechanismsNeuroprotective potentialOxidative stressDiseasePD symptomsHealth benefitsSymptomsUbiquitin
2019
P2‐164: NEUROPROTECTIVE MECHANISM OF SPERMIDINE ALONE AND IN COMBINATION WITH NITRIC OXIDE PATHWAY MODULATORS AGAINST 3‐NP‐INDUCED BEHAVIORAL, BIOCHEMICAL AND NEUROTRANSMITTER ALTERATIONS IN RAT STRIATUM
Jamwal S. P2‐164: NEUROPROTECTIVE MECHANISM OF SPERMIDINE ALONE AND IN COMBINATION WITH NITRIC OXIDE PATHWAY MODULATORS AGAINST 3‐NP‐INDUCED BEHAVIORAL, BIOCHEMICAL AND NEUROTRANSMITTER ALTERATIONS IN RAT STRIATUM. Alzheimer's & Dementia 2019, 15: p638-p638. DOI: 10.1016/j.jalz.2019.06.2571.Peer-Reviewed Original Research
2015
Antidepressants for neuroprotection in Huntington's disease: A review
Jamwal S, Kumar P. Antidepressants for neuroprotection in Huntington's disease: A review. European Journal Of Pharmacology 2015, 769: 33-42. PMID: 26511378, DOI: 10.1016/j.ejphar.2015.10.033.Peer-Reviewed Original ResearchConceptsHuntingtin proteinHuntington's diseaseMAPK/ERK signalingBrain-derived neurotrophic factor (BDNF) productionBDNF/TrkB pathwayProgression of HDDifferent neuroprotective mechanismsPrincipal neuropathological hallmarksUse of antidepressantsNeurotrophic factor productionCortical projection neuronsMutant huntingtin proteinCellular functionsPolyglutamine stretchMolecular mechanismsNH2 terminusERK signalingTrkB pathwayPreclinical evidenceNeuroprotective effectsNeuroprotective mechanismsCommon symptomsProjection neuronsAvailable treatmentsDisease progression