2024
A review on polyamines as promising next-generation neuroprotective and anti-aging therapy
Arthur R, Jamwal S, Kumar P. A review on polyamines as promising next-generation neuroprotective and anti-aging therapy. European Journal Of Pharmacology 2024, 978: 176804. PMID: 38950837, DOI: 10.1016/j.ejphar.2024.176804.Peer-Reviewed Original ResearchCognitive dysfunctionNeurodegenerative disordersRegulation of gene expressionProgressive degeneration of neuronsProgrammed cell deathDegeneration of neuronsSymptomatic therapyPharmacological strategiesAnti-oxidative effectsAnti-aging therapyAverage ageProgressive degenerationNeuroprotective effectsLocomotor abnormalitiesIon channelsCell deathBiochemical activityGene expressionPopulation average ageTherapyMolecular mechanismsDisordersPolyamine supplementationDysfunctionAnti-aging effectsDopamine Transporter Deficiency Syndrome (DTDS)
Jamwal S, Gautam A. Dopamine Transporter Deficiency Syndrome (DTDS). 2024, 1-4. DOI: 10.1007/978-3-319-66816-1_452-1.Peer-Reviewed Original ResearchDopamine transporter deficiency syndromeDopamine transporterMovement disordersHuman dopamine transporterSLC6A3 geneBehavioral symptomsAmbiguous eventsEarly adolescenceSlow speechDisordersHyperkinetic movementsSLC6A3Choreiform movementsAdolescentsEarly childhoodAssociated with poor outcomesLater onsetHypokinetic movementsAffected individualsNon-specific symptomsSymptomsDevelopmental targetsEarly-onsetResting tremorRecurrent movement disorders
2021
Sex-based disparity in paraoxonase-2 expression in the brains of African green monkeys
Jamwal S, Blackburn JK, Elsworth JD. Sex-based disparity in paraoxonase-2 expression in the brains of African green monkeys. Free Radical Biology And Medicine 2021, 167: 201-204. PMID: 33722626, PMCID: PMC8096713, DOI: 10.1016/j.freeradbiomed.2021.03.003.Peer-Reviewed Original ResearchConceptsAfrican green monkeysParaoxonase 2Parkinson's diseaseBrain regionsGreen monkeysOxidative stressReactive oxygen speciesAnti-inflammatory propertiesSex-based disparitiesParaoxonase-2 expressionDifferent brain regionsNigrostriatal systemPON2 expressionDevelopment of therapeuticsNeurodegenerative disordersDiseaseProtein levelsROS levelsLower ROS levelsMitochondrial performanceSex-based variationDisordersMonkeysOxygen speciesMales
2017
Animal Models of Migraine
Jamwal S, Singh S, Bansal P. Animal Models of Migraine. 2017, 105-115. DOI: 10.1007/978-981-10-5981-0_8.Peer-Reviewed Original ResearchAnimal Model of Anxiety
Bansal P, Singh S, Jamwal S. Animal Model of Anxiety. 2017, 139-158. DOI: 10.1007/978-981-10-5981-0_10.Peer-Reviewed Original ResearchEveryday life situationsGeneralized anxiety disorderAnxiety disordersUnrealistic worryPanic disorderAutonomic nervous system arousalLife situationsHuman anxiety disordersPsychological treatmentAnxiety-related behaviorPathological anxietyIntense fearExtreme fearAnxietyBehavioral disturbancesPanic attacksPainful stimuliFearWorryDisordersAnimal modelsArousalSymptomologyStimuliPrimary symptomsAnimal Models of Attention-Deficit Hyperkinetic Disorder (ADHD)
Sharma N, Jamwal S, Bansal P. Animal Models of Attention-Deficit Hyperkinetic Disorder (ADHD). 2017, 217-232. DOI: 10.1007/978-981-10-5981-0_14.Peer-Reviewed Original ResearchAttention deficit hyperkinetic disorderAttention deficit disorderHyperactivity disorderDeficit disorderAttention deficit hyperactivity disorderDeficit hyperactivity disorderCommon childhood-onset neuropsychiatric disorderSchool-aged childrenADHD childrenAttention deficitsChildhood-onset neuropsychiatric disorderChildhood disordersBehavioral disordersSigns of hyperactivityHyperkinetic disorderHyperactivityChildrenTerms of choiceBrain damageNeuropsychiatric disordersDSM-IIIDisordersAdultsInattentionAnimal modelsBehavioral Tests for Rodent Models
Jamwal S, Singh S, Bansal P. Behavioral Tests for Rodent Models. 2017, 315-341. DOI: 10.1007/978-981-10-5981-0_21.Peer-Reviewed Original ResearchMotor coordinationPerformance-based testsTraumatic brain injuryBrain injuryBehavioral testsTesting of drugsMotor activityRotating rodRotarod testGrip strengthMovement disordersRodent modelsAnimal modelsExperimental drugsPreclinical researchDrugsDisordersRodentsTestLatencyResearchRotarodInjuryCoordination