Animal Models of Parkinson’s Disease
Sharma N, Jamwal S, Singh S, Gill H, Bansal P. Animal Models of Parkinson’s Disease. 2017, 23-42. DOI: 10.1007/978-981-10-5981-0_3.Peer-Reviewed Original ResearchParkinson's diseaseDopaminergic neuronsLewy bodiesPrevalence of PDCranial nerve motor nucleiHypokinetic movement disordersNigrostriatal dopaminergic neuronsNon-motor symptomsMajor pathological featureAge related neurodegenerative diseasesRelated neurodegenerative diseasesInheritable genetic mutationsProgressive neurodegenerativeAutonomic dysfunctionOrthostatic hypotensionIdiopathic originNeuropsychiatric disturbancesCerebral cortexMotor manifestationsMotor nucleusNucleus basalisPathological featuresSleep disturbancesLocus coeruleusSelective degenerationAnimal Model of Amyotrophic Lateral Sclerosis
Koshal P, Kumar M, Jamwal S, Bansal P. Animal Model of Amyotrophic Lateral Sclerosis. 2017, 277-289. DOI: 10.1007/978-981-10-5981-0_18.Peer-Reviewed Original ResearchAmyotrophic lateral sclerosisMotor neuronsLateral sclerosisMuscle performancePatients of ALSPrevalence of ALSCases of ALSDepletion of neuronsUpper motor neuronsLower motor neuronsFamilial amyotrophic lateral sclerosisInvolvement of neuronsLou Gehrig's diseaseALS-dementiaCerebral cortexMuscle weaknessSubstantia nigraBrain stemDisease progressionSpinal cordMuscle atrophyAnimal modelsAverage ageCognitive impairmentNeurodegenerative disorders