2019
816-P: Pediatric Preferences for an Ideal Artificial Pancreas (AP): Unique Features to Reduce Self-Care Burdens of Type 1 Diabetes (T1D)
COMMISSARIAT P, ROETHKE L, VOLKENING L, BUTLER D, FINNEGAN J, DASSAU E, WEINZIMER S, LAFFEL L. 816-P: Pediatric Preferences for an Ideal Artificial Pancreas (AP): Unique Features to Reduce Self-Care Burdens of Type 1 Diabetes (T1D). Diabetes 2019, 68 DOI: 10.2337/db19-816-p.Peer-Reviewed Original ResearchDiabetes careBurden of T1DSelf-care burdenDiabetes technologyType 1 diabetesEli LillyArtificial pancreasUnderwent thematic analysisT1D durationNovo Nordisk A/SCarbohydrate countingSpouse/partnerCare burdenSemi-structured qualitative interviewsT1D careJanssen PharmaceuticalsMedtronic MiniMedPatients' hopeAP uptakeHeart rate monitorT1DDiabetesYoung adultsSpeakers bureauCare
2017
Expectations and Attitudes of Individuals With Type 1 Diabetes After Using a Hybrid Closed Loop System
Iturralde E, Tanenbaum ML, Hanes SJ, Suttiratana SC, Ambrosino JM, Ly TT, Maahs DM, Naranjo D, Walders-Abramson N, Weinzimer SA, Buckingham BA, Hood KK. Expectations and Attitudes of Individuals With Type 1 Diabetes After Using a Hybrid Closed Loop System. The Science Of Diabetes Self-Management And Care 2017, 43: 223-232. PMID: 28340542, PMCID: PMC7162535, DOI: 10.1177/0145721717697244.Peer-Reviewed Original ResearchConceptsType 1 diabetesHybrid closed-loop systemFirst hybrid closed-loop systemLong-term complicationsGlycemic controlClinical trialsUS FoodDrug AdministrationMethods ThirtyDiabetesLife benefitsInsulin deliveryMental burdenT1DArtificial pancreasConclusion UsersAttitudes of individualsFocus groupsPerceived benefitsIndividualsComplicationsPancreasCliniciansAdministrationTrials
2016
Outcome Measures for Artificial Pancreas Clinical Trials: A Consensus Report
Maahs DM, Buckingham BA, Castle JR, Cinar A, Damiano ER, Dassau E, DeVries JH, Doyle FJ, Griffen SC, Haidar A, Heinemann L, Hovorka R, Jones TW, Kollman C, Kovatchev B, Levy BL, Nimri R, O’Neal D, Philip M, Renard E, Russell SJ, Weinzimer SA, Zisser H, Lum JW. Outcome Measures for Artificial Pancreas Clinical Trials: A Consensus Report. Diabetes Care 2016, 39: 1175-1179. PMID: 27330126, PMCID: PMC4915553, DOI: 10.2337/dc15-2716.Peer-Reviewed Original Research
2013
The Impact of Insulin Pharmacokinetics and Pharmacodynamics on the Closed-loop Artificial Pancreas
Lee J, Dassau E, Zisser H, Tamborlane W, Weinzimer S, Doyle F. The Impact of Insulin Pharmacokinetics and Pharmacodynamics on the Closed-loop Artificial Pancreas. 2013, 127-132. DOI: 10.1109/cdc.2013.6759870.Peer-Reviewed Original ResearchInsulin delivery optionsPK/PD characteristicsClinical performanceArtificial pancreasPK/PDMeal disturbance rejectionClosed-loop artificial pancreasPharmacodynamic characteristicsClinical resultsGlucose regulationInsulin pharmacokineticsDelivery optionsPancreasOptionsUniversity of VirginiaMetabolic simulatorPharmacodynamicsPharmacokinetics
2008
Fully Automated Closed-Loop Insulin Delivery Versus Semiautomated Hybrid Control in Pediatric Patients With Type 1 Diabetes Using an Artificial Pancreas
Weinzimer SA, Steil GM, Swan KL, Dziura J, Kurtz N, Tamborlane WV. Fully Automated Closed-Loop Insulin Delivery Versus Semiautomated Hybrid Control in Pediatric Patients With Type 1 Diabetes Using an Artificial Pancreas. Diabetes Care 2008, 31: 934-939. PMID: 18252903, DOI: 10.2337/dc07-1967.Peer-Reviewed Original ResearchConceptsType 1 diabetesGlucose levelsHCl groupFCL groupInsulin pumpBeta cell replacement therapyPostprandial glycemic excursionsPostprandial glucose excursionsPostprandial glucose levelsClosed-loop glucose controlArtificial pancreasClosed-loop artificial pancreasPediatric patientsPostprandial excursionsBolus dosesGlycemic excursionsReplacement therapySubcutaneous routeGlucose controlGlucose excursionsInsulin delivery systemsHybrid closed-loop controlInsulin absorptionType 1Dl
2004
Diabetes Mellitus in Children and Adolescents
Weinzimer S, Tamborlane W. Diabetes Mellitus in Children and Adolescents. 2004 DOI: 10.1002/0470862092.d0809.Peer-Reviewed Original ResearchDiabetes mellitusNormal glucose controlRoutine clinical practiceSpecific clinical presentationType 2 diabetesType 1 diabetesQuality of lifeOutpatient managementClinical presentationTreatment algorithmGlucose controlDifferential diagnosisClinical practiceMellitusDiabetesInsulin deliveryPresent unique challengesChildrenArtificial pancreasDiagnosisTreatmentUnique challengesPancreasPrevalenceClinicians