1996
Autoprotective mechanisms in the CNS
Fern R, Ransom B, Waxman S. Autoprotective mechanisms in the CNS. Journal Of Molecular Neuroscience 1996, 27: 107-129. PMID: 8962597, DOI: 10.1007/bf02815088.Peer-Reviewed Original Research
1995
Anoxic/ischemic injury in axons
STYS P, RANSOM B, BLACK J, WAXMAN S. Anoxic/ischemic injury in axons. 1995, 462-479. DOI: 10.1093/acprof:oso/9780195082937.003.0024.Peer-Reviewed Original ResearchNerve fibersNervous systemAnoxic/ischemic injuryPeripheral nervous systemAnoxia/ischemiaCentral nervous systemIschemic injuryPeripheral axonsAction potential propagationAxonsNormal functionPathological statesBiochemical homeostasisTransmembrane ion gradientsCellular energy metabolismInjuryEnergy metabolismPotential propagationSurvivalHuman diseasesMajor mechanismIon gradientsMembrane polarizationIschemiaDisease
1994
Anoxic Injury of Central Myelinated Axons: Nonsynaptic Ionic Mechanisms
Ransom B, Waxman S, Stys P. Anoxic Injury of Central Myelinated Axons: Nonsynaptic Ionic Mechanisms. 1994, 77-90. DOI: 10.1007/978-3-642-78151-3_9.Peer-Reviewed Original ResearchGlial cellsAnoxic injuryWhite matterCentral nervous system traumaIrreversible anoxic injuryPathophysiology of strokeNervous system traumaCentral myelinated axonsNeuronal cell bodiesAnoxia/ischemiaGray matter areasCNS axonal injuryNeuronal injuryIonic mechanismsAxonal injurySystem traumaCell injuryMyelinated axonsInjuryCell bodiesAxonsMatter areasBrainMetabolic substratesReliable model system
1992
Ionic mechanisms of anoxic injury in mammalian CNS white matter: role of Na+ channels and Na(+)-Ca2+ exchanger
Stys P, Waxman S, Ransom B. Ionic mechanisms of anoxic injury in mammalian CNS white matter: role of Na+ channels and Na(+)-Ca2+ exchanger. Journal Of Neuroscience 1992, 12: 430-439. PMID: 1311030, PMCID: PMC6575619, DOI: 10.1523/jneurosci.12-02-00430.1992.Peer-Reviewed Original ResearchConceptsRat optic nerveCompound action potentialAnoxic injuryOptic nerveWhite matterAction potentialsCentral white matter tractsWhite matter injuryCNS white matterMembrane depolarizationAnoxia/ischemiaWhite matter tractsCNS protectionAnoxic insultMyelinated tractsChannel blockersExchanger blockerIrreversible injuryExtracellular Ca2Mammalian CNSNerveInjuryMore injuriesBlockersFunctional integrity