2006
RanBPM Contributes to Semaphorin3A Signaling through Plexin-A Receptors
Togashi H, Schmidt EF, Strittmatter SM. RanBPM Contributes to Semaphorin3A Signaling through Plexin-A Receptors. Journal Of Neuroscience 2006, 26: 4961-4969. PMID: 16672672, PMCID: PMC2846289, DOI: 10.1523/jneurosci.0704-06.2006.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Signal TransducingAnimalsCell Adhesion MoleculesCell DeathCell SizeCells, CulturedChick EmbryoCloning, MolecularCricetinaeCricetulusCytoskeletal ProteinsDose-Response Relationship, DrugDrug InteractionsEnzyme InhibitorsGanglia, SpinalGene ExpressionGreen Fluorescent ProteinsHumansImmunoprecipitationIn Situ Nick-End LabelingNerve Tissue ProteinsNeuritesNeuronsNeuropilin-1Nuclear ProteinsRan GTP-Binding ProteinSemaphorin-3ASignal TransductionTranscription Factor AP-1TransfectionTwo-Hybrid System TechniquesConceptsPlexin-A1Collapsin response mediator proteinsNervous system developmentReceptor complex consistingSignal transductionRanBPMMediator proteinsMicrotubule functionCell spreadingComplex consistingAxonal guidanceNeuronal cellsAxonal guidance cuesProteinGuidance cuesPlexinsAxonal outgrowthExpressionSema3ATransductionReceptorsDomainOverexpressionNeuropilinsSystem development
2001
Semaphorin-mediated axonal guidance via Rho-related G proteins
Liu B, Strittmatter S. Semaphorin-mediated axonal guidance via Rho-related G proteins. Current Opinion In Cell Biology 2001, 13: 619-626. PMID: 11544032, DOI: 10.1016/s0955-0674(00)00260-x.Peer-Reviewed Original ResearchPlexinA1 Autoinhibition by the Plexin Sema Domain
Takahashi T, Strittmatter S. PlexinA1 Autoinhibition by the Plexin Sema Domain. Neuron 2001, 29: 429-439. PMID: 11239433, DOI: 10.1016/s0896-6273(01)00216-1.Peer-Reviewed Original Research
2000
Molecular basis of semaphorin‐mediated axon guidance
Nakamura F, Kalb R, Strittmatter S. Molecular basis of semaphorin‐mediated axon guidance. Developmental Neurobiology 2000, 44: 219-229. PMID: 10934324, DOI: 10.1002/1097-4695(200008)44:2<219::aid-neu11>3.0.co;2-w.Peer-Reviewed Original ResearchConceptsGrowth cone collapseSemaphorin guidance cuesMonomeric G proteinsSignal transduction cascadeGuidance cuesAxon guidance eventsCone collapseGrowth cone motilityCaenorhabditis elegansActin cytoskeletonTransmembrane proteinFilopodial tipsNeuropilin-1Transduction cascadeMolecular basisComplex interactsIntracellular domainPrototypic memberGrowth cone turningRac1 activityAxon guidanceG proteinsRepulsive guidance cuesNeuronal proteinsAxonal guidanceSemaphorin3a Enhances Endocytosis at Sites of Receptor–F-Actin Colocalization during Growth Cone Collapse
Fournier A, Nakamura F, Kawamoto S, Goshima Y, Kalb R, Strittmatter S. Semaphorin3a Enhances Endocytosis at Sites of Receptor–F-Actin Colocalization during Growth Cone Collapse. Journal Of Cell Biology 2000, 149: 411-422. PMID: 10769032, PMCID: PMC2175148, DOI: 10.1083/jcb.149.2.411.Peer-Reviewed Original ResearchDendrites go up, axons go down
Strittmatter S. Dendrites go up, axons go down. Nature 2000, 404: 557-559. PMID: 10766224, DOI: 10.1038/35007181.Peer-Reviewed Original Research
1999
Plexin-Neuropilin-1 Complexes Form Functional Semaphorin-3A Receptors
Takahashi T, Fournier A, Nakamura F, Wang L, Murakami Y, Kalb R, Fujisawa H, Strittmatter S. Plexin-Neuropilin-1 Complexes Form Functional Semaphorin-3A Receptors. Cell 1999, 99: 59-69. PMID: 10520994, DOI: 10.1016/s0092-8674(00)80062-8.Peer-Reviewed Original ResearchGrowth cone neuropilin‐1 mediates collapsin‐1/sema III facilitation of antero‐ and retrograde axoplasmic transport
Goshima Y, Hori H, Sasaki Y, Yang T, Maezono M, Li C, Takenaka T, Nakamura F, Takahashi T, Strittmatter S, Misu Y, Kawakami T. Growth cone neuropilin‐1 mediates collapsin‐1/sema III facilitation of antero‐ and retrograde axoplasmic transport. Developmental Neurobiology 1999, 39: 579-589. PMID: 10380079, DOI: 10.1002/(sici)1097-4695(19990615)39:4<579::aid-neu11>3.0.co;2-9.Peer-Reviewed Original Research
1998
Neuropilin-1 Extracellular Domains Mediate Semaphorin D/III-Induced Growth Cone Collapse
Nakamura F, Tanaka M, Takahashi T, Kalb R, Strittmatter S. Neuropilin-1 Extracellular Domains Mediate Semaphorin D/III-Induced Growth Cone Collapse. Neuron 1998, 21: 1093-1100. PMID: 9856464, DOI: 10.1016/s0896-6273(00)80626-1.Peer-Reviewed Original ResearchSemaphorins A and E act as antagonists of neuropilin-1 and agonists of neuropilin-2 receptors
Takahashi T, Nakamura F, Jin Z, Kalb R, Strittmatter S. Semaphorins A and E act as antagonists of neuropilin-1 and agonists of neuropilin-2 receptors. Nature Neuroscience 1998, 1: 487-493. PMID: 10196546, DOI: 10.1038/2203.Peer-Reviewed Original Research