2013
Multimodal exercises simultaneously stimulating cortical and brainstem pathways after unilateral corticospinal lesion
Harel NY, Yigitkanli K, Fu Y, Cafferty WB, Strittmatter SM. Multimodal exercises simultaneously stimulating cortical and brainstem pathways after unilateral corticospinal lesion. Brain Research 2013, 1538: 17-25. PMID: 24055330, PMCID: PMC3873870, DOI: 10.1016/j.brainres.2013.07.012.Peer-Reviewed Original ResearchConceptsBrainstem pathwaysMultimodal exerciseCorticospinal tractTraining groupContext of injuryCST pathwayAnatomical outcomesCST injuryPostural exercisesCorticospinal lesionsCollateral sproutingCST lesionElectrophysiological assessmentSpinal cordPhysical exerciseGait kinematicsLimb performanceSynaptic strengthLesionsSubcortical circuitsFiber densityMiceInjuryFurther studiesExercise
2006
Can regenerating axons recapitulate developmental guidance during recovery from spinal cord injury?
Harel NY, Strittmatter SM. Can regenerating axons recapitulate developmental guidance during recovery from spinal cord injury? Nature Reviews Neuroscience 2006, 7: 603-616. PMID: 16858389, PMCID: PMC2288666, DOI: 10.1038/nrn1957.Peer-Reviewed Original ResearchConceptsCNS regenerationNervous systemCentral pattern generatorImmature nervous systemSpinal cord injuryRegeneration-associated genesMammalian CNS regenerationContext of injuryExperience-dependent plasticityFurther plastic changesInflammatory cellsCord injuryVoluntary inputNervous system developmentRegenerating axonsSensory feedbackInhibitory barrierPlastic changesInhibitory moleculesRegenerative responseGuidance moleculesAltered distributionNeuronal branchesInjuryGuidance factors