2009
Serum Nogo-A levels are not elevated in amyotrophic lateral sclerosis patients
Harel NY, Cudkowicz ME, Brown RH, Strittmatter SM. Serum Nogo-A levels are not elevated in amyotrophic lateral sclerosis patients. Biomarkers 2009, 14: 414-417. PMID: 19548774, PMCID: PMC2842187, DOI: 10.1080/13547500903056051.Peer-Reviewed Original ResearchConceptsAmyotrophic lateral sclerosisALS patientsHealthy controlsAmyotrophic lateral sclerosis patientsHealthy control seraInvasive diagnostic methodsSclerosis patientsLateral sclerosisPatientsControl seraMuscle contentSerum samplesElevated levelsAdditional studiesSerumDiagnostic methodsLarge percentageSclerosisLevelsDiagnosisControlBiomarkersNogoNM
2003
The Nogo-66 receptor: focusing myelin inhibition of axon regeneration
McGee AW, Strittmatter SM. The Nogo-66 receptor: focusing myelin inhibition of axon regeneration. Trends In Neurosciences 2003, 26: 193-198. PMID: 12689770, DOI: 10.1016/s0166-2236(03)00062-6.Peer-Reviewed Original ResearchMeSH KeywordsAcute-Phase ProteinsAnimalsAxonsCells, CulturedGPI-Linked ProteinsHumansIn Vitro TechniquesMiceMyelin ProteinsMyelin SheathMyelin-Associated GlycoproteinMyelin-Oligodendrocyte GlycoproteinNerve RegenerationNeural InhibitionNeuronal PlasticityNogo ProteinsNogo Receptor 1RatsReceptor, Nerve Growth FactorReceptors, Cell SurfaceReceptors, Nerve Growth FactorSignal TransductionConceptsNogo-66 receptorMembrane protein NogoSpinal cord injuryFunctional recoveryCord injuryAxonal regrowthSecond messenger pathwaysProtein NogoAdult CNSAxon regenerationMyelin inhibitionAxonal outgrowthAdditional studiesCNS myelinMyelinNeurite elongationPhysiological roleReceptorsMolecular determinantsInhibitorsInhibitionNGRCurrent understanding