Appetitive startle modulation in the human laboratory predicts Cannabis craving in the natural environment
Mereish EH, Padovano HT, Wemm S, Miranda R. Appetitive startle modulation in the human laboratory predicts Cannabis craving in the natural environment. Psychopharmacology 2018, 235: 1933-1943. PMID: 29623354, PMCID: PMC6015780, DOI: 10.1007/s00213-018-4890-z.Peer-Reviewed Original ResearchConceptsCue-elicited cravingStartle reactivityEcological momentary assessment protocolHuman laboratoryCannabis-related stimuliCannabis-related cuesFrequent cannabis usersCross-level interactionsCannabis cuesResultsMultilevel modelsDrug cuesMotivational processesResponse patternsMotivational systemsPicture cuesPleasant stimuliStartle modulationCannabis usersCannabis useCuesStartle magnitudeCravingReal-world environmentsAge 16Startle reflexPredictors of Topiramate Tolerability in Heavy Cannabis–Using Adolescents and Young Adults
Gray JC, Padovano H, Wemm SE, Miranda R. Predictors of Topiramate Tolerability in Heavy Cannabis–Using Adolescents and Young Adults. Journal Of Clinical Psychopharmacology 2018, 38: 134-137. PMID: 29424802, PMCID: PMC5825284, DOI: 10.1097/jcp.0000000000000843.Peer-Reviewed Original ResearchConceptsMemory difficultiesCannabis misuseYoung adultsPsychosocial treatment optionsSubstance use disordersPsychosocial interventionsCannabis problemsHeavy cannabisTreatment dropoutOverwhelming predictorPositive outcomesUse disordersEffective interventionsAdolescentsSide effectsMedication conditionRandomized placebo-controlled trialInteraction effectsSubstance abuse treatment admissionsTreatment admissionsPlacebo-controlled trialSecondary data analysisRecent clinical trialsIllicit drugsAdults