2017
Two Disease-Causing SNAP-25B Mutations Selectively Impair SNARE C-terminal Assembly
Rebane AA, Wang B, Ma L, Qu H, Coleman J, Krishnakumar S, Rothman JE, Zhang Y. Two Disease-Causing SNAP-25B Mutations Selectively Impair SNARE C-terminal Assembly. Journal Of Molecular Biology 2017, 430: 479-490. PMID: 29056461, PMCID: PMC5805579, DOI: 10.1016/j.jmb.2017.10.012.Peer-Reviewed Original ResearchConceptsSoluble N-ethylmaleimide-sensitive factor attachment receptorSNARE assemblySynaptic exocytosisMembrane fusionSingle-molecule optical tweezersT-SNARE complexVesicle-associated SNAREsTarget plasma membraneC-terminal assemblyFour-helix bundleC-terminal regionSNARE complexPlasma membraneMolecular mechanismsZipperingMutationsNumerous diseasesAssembly energyNeurotransmitter releaseExocytosisAttachment receptorAssemblyNeurological disordersOptical tweezersComplexes
2007
The Control of Transmembrane Helix Transverse Position in Membranes by Hydrophilic Residues
Krishnakumar SS, London E. The Control of Transmembrane Helix Transverse Position in Membranes by Hydrophilic Residues. Journal Of Molecular Biology 2007, 374: 1251-1269. PMID: 17997412, PMCID: PMC2175128, DOI: 10.1016/j.jmb.2007.10.032.Peer-Reviewed Original Research
2002
Spatial Relationship between the Prodan Site, Trp-214, and Cys-34 Residues in Human Serum Albumin and Loss of Structure through Incremental Unfolding †
Krishnakumar SS, Panda D. Spatial Relationship between the Prodan Site, Trp-214, and Cys-34 Residues in Human Serum Albumin and Loss of Structure through Incremental Unfolding †. Biochemistry 2002, 41: 7443-7452. PMID: 12044178, DOI: 10.1021/bi025699v.Peer-Reviewed Original Research