Perspective on Clinical Application of Biomarkers in AKI
Parikh CR, Mansour SG. Perspective on Clinical Application of Biomarkers in AKI. Journal Of The American Society Of Nephrology 2017, 28: 1677-1685. PMID: 28220028, PMCID: PMC5461806, DOI: 10.1681/asn.2016101127.Peer-Reviewed Original ResearchConceptsPrognosis of AKIAvailable clinical markersClinical applicationWidespread clinical applicabilityRenal injurySerum creatinineClinical markersRepair biomarkersClinical diagnosisManagement dilemmaBiomarker performanceBiomarkersClinical applicabilityAKIBiomarker dataInjuryCreatininePrognosisDiagnosisBiomarkers for the detection of renal fibrosis and prediction of renal outcomes: a systematic review
Mansour SG, Puthumana J, Coca SG, Gentry M, Parikh CR. Biomarkers for the detection of renal fibrosis and prediction of renal outcomes: a systematic review. BMC Nephrology 2017, 18: 72. PMID: 28219345, PMCID: PMC5319065, DOI: 10.1186/s12882-017-0490-0.Peer-Reviewed Original ResearchConceptsMatrix metalloproteinase-2Renal outcomesRenal functionRenal fibrosisStage ISystematic reviewWorse renal outcomeChronic kidney diseaseBiomarkers of fibrosisChemoattractant protein-1Diverse patient populationsGrowth factor βUrine biomarkersKidney diseaseMCP-1Patient populationDisease progressionMetalloproteinase-2FibrosisModerate positive correlationStage IIPatientsUnifying pathwayBiomarkersReliability of blood