2019
Association of T Cell–Derived Inflammatory Cytokines With Acute Kidney Injury and Mortality After Cardiac Surgery
Moledina DG, Mansour SG, Jia Y, Obeid W, Thiessen-Philbrook H, Koyner JL, McArthur E, Garg AX, Wilson FP, Shlipak MG, Coca SG, Parikh CR, Consortium T. Association of T Cell–Derived Inflammatory Cytokines With Acute Kidney Injury and Mortality After Cardiac Surgery. Kidney International Reports 2019, 4: 1689-1697. PMID: 31844805, PMCID: PMC6895592, DOI: 10.1016/j.ekir.2019.09.003.Peer-Reviewed Original ResearchAcute kidney injuryIschemia-reperfusion injuryCardiac surgeryKidney injuryIL-13IL-4Higher oddsT cell-derived inflammatory cytokinesPostoperative acute kidney injuryRenal ischemia-reperfusion injuryTh2 biomarkersObservational cohortPreoperative levelsT helperTh2 pathwayClinical outcomesTh2 cytokinesClinical variablesInflammatory cytokinesIndependent associationPlasma biomarkersTh2 cellsSurgeryAnimal modelsMortality
2017
Associations Between Deceased-Donor Urine MCP-1 and Kidney Transplant Outcomes
Mansour SG, Puthumana J, Reese PP, Hall IE, Doshi MD, Weng FL, Schröppel B, Thiessen-Philbrook H, Bimali M, Parikh CR. Associations Between Deceased-Donor Urine MCP-1 and Kidney Transplant Outcomes. Kidney International Reports 2017, 2: 749-758. PMID: 28730184, PMCID: PMC5512592, DOI: 10.1016/j.ekir.2017.03.007.Peer-Reviewed Original ResearchDelayed graft functionAcute kidney injuryMonocyte chemoattractant protein-1MCP-1 concentrationsUMCP-1Graft failureDonor Acute Kidney InjuryRecipient delayed graft functionUrine MCP-1Deceased kidney donorsKidney transplant outcomesChemoattractant protein-1Organ procurement organizationsMinimal clinical utilityAllograft functionAllograft outcomesGraft functionKidney injuryTransplant outcomesKidney procurementStudy cohortKidney donorsIndependent associationMacrophage recruitmentClinical utility