2013
Ventromedial prefrontal cortex and the regulation of physiological arousal
Zhang S, Hu S, Chao HH, Ide JS, Luo X, Farr OM, Li CS. Ventromedial prefrontal cortex and the regulation of physiological arousal. Social Cognitive And Affective Neuroscience 2013, 9: 900-908. PMID: 23620600, PMCID: PMC4090954, DOI: 10.1093/scan/nst064.Peer-Reviewed Original ResearchConceptsSkin conductance levelVentromedial prefrontal cortexPrefrontal cortexDorsal anterior cingulate cortexCausal roleAnterior cingulate cortexFunctional magnetic resonance imagingMagnetic resonance imagingCerebral blood oxygenationSkin conductance measurementsHealthy adultsPhysiological arousalUnderstanding of dysfunctionCingulate cortexResonance imagingBrain regionsBlood oxygenationAnxiety disordersAltered controlCortexGranger causality analysisSkin conductance responsesBehavioral tasksPhasic skin conductance responsesSkin conductanceError processing and gender-shared and -specific neural predictors of relapse in cocaine dependence
Luo X, Zhang S, Hu S, Bednarski SR, Erdman E, Farr OM, Hong KI, Sinha R, Mazure CM, Li CS. Error processing and gender-shared and -specific neural predictors of relapse in cocaine dependence. Brain 2013, 136: 1231-1244. PMID: 23485852, PMCID: PMC3613717, DOI: 10.1093/brain/awt040.Peer-Reviewed Original ResearchConceptsDorsal anterior cingulate cortexFunctional magnetic resonance imagingCognitive controlError-related activationError processingCocaine-dependent individualsAnterior cingulate cortexSignal taskCingulate cortexCocaine dependenceFunctional magnetic resonance imaging (fMRI) dataStop-signal taskTreatment-seeking individualsCross-sectional findingsModerate-sized cohortsBrain activationBehavioral treatmentNeural predictorsDrug useMagnetic resonance imaging dataStatistical Parametric Mapping 8Regional activationPsychosocial factorsSuccess trialsMagnetic resonance imaging
2012
Cerebral correlates of skin conductance responses in a cognitive task
Zhang S, Hu S, Chao HH, Luo X, Farr OM, Li CS. Cerebral correlates of skin conductance responses in a cognitive task. NeuroImage 2012, 62: 1489-1498. PMID: 22634217, PMCID: PMC3408848, DOI: 10.1016/j.neuroimage.2012.05.036.Peer-Reviewed Original ResearchConceptsSkin conductance responsesSupplementary motor areaControl of arousalDorsal anterior cingulate cortexAnterior cingulate cortexRegional activationFunctional magnetic resonance imagingMagnetic resonance imagingMedial prefrontal cortexLower skin conductance responsesMotor areaCingulate cortexResonance imagingPrefrontal cortexCerebral correlatesConductance responsesTrialsSuccess trialsNeural activityStop successSignal taskPhysiological arousalCognitive performanceNeural correlatesCortexTask-Related, Low-Frequency Task-Residual, and Resting State Activity in the Default Mode Network Brain Regions
Zhang S, Li CS. Task-Related, Low-Frequency Task-Residual, and Resting State Activity in the Default Mode Network Brain Regions. Frontiers In Psychology 2012, 3: 172. PMID: 22661964, PMCID: PMC3362743, DOI: 10.3389/fpsyg.2012.00172.Peer-Reviewed Original ResearchDefault mode networkPosterior cingulate cortexBlood oxygen level-dependent (BOLD) signalLow-frequency fluctuation (fALFF) signalsLevel-dependent signalStop-signal taskCingulate cortexBrain regionsBrain functionTask-related eventsFractional amplitudePrecuneusMode networkDMN regionsSignal taskDMN activityBrain activityCognitive performanceUseful indexLatter findingRestingDMN responseTask eventsTask conditionsFALFF
2011
Deficits in default mode network activity preceding error in cocaine dependent individuals
Bednarski SR, Zhang S, Hong KI, Sinha R, Rounsaville BJ, Li CS. Deficits in default mode network activity preceding error in cocaine dependent individuals. Drug And Alcohol Dependence 2011, 119: e51-e57. PMID: 21703783, PMCID: PMC3188675, DOI: 10.1016/j.drugalcdep.2011.05.026.Peer-Reviewed Original ResearchConceptsDefault mode networkCocaine dependenceCocaine useHealthy controlsTask-related cerebral activationBlood oxygenation level-dependent (BOLD) signalDemographics-matched healthy controlsGray matter volumeDefault mode network activityLevel-dependent signalChronic cocaine useRegional brain activationPosterior cingulate cortexStatistical parametric mappingCerebral functionBilateral precuneusCocaine-dependent individualsCerebral activationHealthy peopleMatter volumeCingulate cortexVentromedial prefrontal cortexBrain regionsCognitive deficitsCocaine misuse
2009
A neural measure of behavioral engagement: Task-residual low-frequency blood oxygenation level-dependent activity in the precuneus
Zhang S, Li CS. A neural measure of behavioral engagement: Task-residual low-frequency blood oxygenation level-dependent activity in the precuneus. NeuroImage 2009, 49: 1911-1918. PMID: 19761851, PMCID: PMC2791356, DOI: 10.1016/j.neuroimage.2009.09.004.Peer-Reviewed Original ResearchConceptsBlood oxygenation level-dependent activityRegional brain activationLevel-dependent activityTask engagementNeural measuresNeural processesBrain activationPosterior cingulate cortexAttentional monitoringResponse inhibitionHuman cognitionPrefrontal activationSignal taskGreater activationBOLD activityBehavioral engagementCingulate cortexPrecuneusBrain regionsLow-frequency fluctuationsFractional amplitudeBrain imagingSeed regionIndependent component analysisEngagement